Search Results - "Castell, Wolfgang zu"
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Sulfonolipids as novel metabolite markers of Alistipes and Odoribacter affected by high-fat diets
Published in Scientific reports (08-09-2017)“…The gut microbiota generates a huge pool of unknown metabolites, and their identification and characterization is a key challenge in metabolomics. However,…”
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Systemic analysis of a developing plant community on the island of Surtsey
Published in Ecology and society (01-03-2022)“…Based on our recently developed method to quantify Gunderson and Holling's adaptive cycle, we provide a holistic analysis of a vascular plant community on the…”
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Distinct signatures of host–microbial meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet
Published in The ISME Journal (01-12-2014)“…A combinatory approach using metabolomics and gut microbiome analysis techniques was performed to unravel the nature and specificity of metabolic profiles…”
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Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production
Published in Microbiome (26-04-2016)“…The development of anti-islet cell autoimmunity precedes clinical type 1 diabetes and occurs very early in life. During this early period, dietary factors…”
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FEATURE SELECTION GUIDED BY STRUCTURAL INFORMATION
Published in The annals of applied statistics (01-06-2010)“…In generalized linear regression problems with an abundant number of features, lasso-type regularization which imposes an 𝓁¹-constraint on the regression…”
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Computing the adaptive cycle
Published in Scientific reports (23-10-2020)“…Gunderson’s and Holling’s adaptive cycle metaphor provides a qualitative description of the development of a dynamically evolving complex system. According to…”
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QtAC: An R-package for analyzing complex systems development in the framework of the adaptive cycle metaphor
Published in Ecological modelling (01-04-2022)“…We present the QtAC R-package, which enables the analysis and assessment of general complex systems in terms of the adaptive cycle metaphor. According to the…”
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Function spaces for conditionally positive definite operator-valued kernels
Published in Mathematics of computation (01-09-2012)“…The correspondence between reproducing kernel Hilbert spaces and positive definite kernels is well understood since Aronszajn's work of the 1940s. The analog…”
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Volatile profiles of fungi – Chemotyping of species and ecological functions
Published in Fungal genetics and biology (01-05-2013)“…► We analyzed the volatomes of 4 ectomycorrhizal, 3 pathogenic and 2 saprophytic fungi. ► We detected 54, including 15 novel VOCs from the different ecological…”
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A novel approach for the analysis of longitudinal profiles reveals delayed progression to type 1 diabetes in a subgroup of multiple-islet-autoantibody-positive children
Published in Diabetologia (01-10-2016)“…Aims/hypothesis Progression to type 1 diabetes in children and adolescents is not uniform. Based on individual genetic background and environment, islet…”
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Gut Immunity and Type 1 Diabetes: a Mélange of Microbes, Diet, and Host Interactions?
Published in Current Diabetes Reports (01-07-2016)“…Type 1 diabetes (T1D) is a complex autoimmune disease, and first stages of the disease typically develop early in life. Genetic as well as environmental…”
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Journal Article Book Review -
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Efficient Detection of Longitudinal Bacteria Fission Using Transfer Learning in Deep Neural Networks
Published in Frontiers in microbiology (08-06-2021)“…A very common way to classify bacteria is through microscopic images. Microscopic cell counting is a widely used technique to measure microbial growth. To…”
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A Cloud-Based Framework for Machine Learning Workloads and Applications
Published in IEEE access (2020)“…In this paper we propose a distributed architecture to provide machine learning practitioners with a set of tools and cloud services that cover the whole…”
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Emphysema- and airway-dominant COPD phenotypes defined by standardised quantitative computed tomography
Published in The European respiratory journal (01-07-2016)“…EvA (Emphysema versus Airway disease) is a multicentre project to study mechanisms and identify biomarkers of emphysema and airway disease in chronic…”
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Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes
Published in Scientific reports (18-06-2021)“…Chronic obstructive pulmonary disease (COPD) is a destructive inflammatory disease and the genes expressed within the lung are crucial to its pathophysiology…”
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AERS spider: an online interactive tool to mine statistical associations in Adverse Event Reporting System
Published in Pharmacoepidemiology and drug safety (01-08-2014)“…ABSTRACT Background Exploration of the Adverse Event Reporting System (AERS) data by a wide scientific community is limited due to several factors. First, AERS…”
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Experimental ‘omics’ data in tree research: facing complexity
Published in Trees (Berlin, West) (01-12-2012)“…High-throughput experimental technology has provided insight into the inner functioning of plants. The current experimental technology facilitates the study of…”
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Thinplate Splines on the Sphere
Published in Symmetry, integrability and geometry, methods and applications (01-01-2018)“…In this paper we give explicit closed forms for the semi-reproducing kernels associated with thinplate spline interpolation on the sphere. Polyharmonic or…”
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Compromised Gut Microbiota Networks in Children With Anti-Islet Cell Autoimmunity
Published in Diabetes (New York, N.Y.) (01-06-2014)“…The gut microbiome is suggested to play a role in the pathogenesis of autoimmune disorders such as type 1 diabetes. Evidence of anti-islet cell autoimmunity in…”
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Dynamics of glucose and insulin concentration connected to the β-cell cycle: model development and analysis
Published in Theoretical biology and medical modelling (19-11-2012)“…Diabetes mellitus is a group of metabolic diseases with increased blood glucose concentration as the main symptom. This can be caused by a relative or a total…”
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