Search Results - "Castejón, Miguel Angel"
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Extracellular Vesicles from Adipose-Derived Mesenchymal Stem Cells Downregulate Senescence Features in Osteoarthritic Osteoblasts
Published in Oxidative medicine and cellular longevity (01-01-2017)“…Osteoarthritis (OA) affects all articular tissues leading to pain and disability. The dysregulation of bone metabolism may contribute to the progression of…”
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Heme oxygenase-1 mediates protective effects on inflammatory, catabolic and senescence responses induced by interleukin-1β in osteoarthritic osteoblasts
Published in Biochemical pharmacology (01-02-2012)“…Osteoarthritis (OA) is a chronic degenerative joint disease showing altered bone metabolism. Osteoblasts contribute to the regulation of cartilage metabolism…”
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Role of peroxiredoxin 6 in the chondroprotective effects of microvesicles from human adipose tissue-derived mesenchymal stem cells
Published in Journal of orthopaedic translation (01-09-2021)“…Osteoarthritis (OA) is a joint disease characterized by cartilage degradation, low-grade synovitis and subchondral bone alterations. In the damaged joint,…”
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Control of cell migration and inflammatory mediators production by CORM-2 in osteoarthritic synoviocytes
Published in PloS one (22-09-2011)“…Osteoarthritis (OA) is the most widespread degenerative joint disease. Inflamed synovial cells contribute to the release of inflammatory and catabolic…”
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Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytes
Published in Aging (Albany, NY.) (01-08-2016)“…Aging and exposure to stress would determine the chondrocyte phenotype in osteoarthritis (OA). In particular, chronic inflammation may contribute to…”
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Anti-senescence and Anti-inflammatory Effects of the C-terminal Moiety of PTHrP Peptides in OA Osteoblasts
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-05-2017)“…Osteoarthritis (OA) is characterized by degenerative changes in the whole joint leading to physical disability in the elderly population. This condition is…”
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Heme oxygenase-1 induction modulates microsomal prostaglandin E synthase-1 expression and prostaglandin E2 production in osteoarthritic chondrocytes
Published in Biochemical pharmacology (15-06-2009)“…Pro-inflammatory cytokines such as interleukin-1β (IL-1β) may participate in the pathogenesis of cartilage damage in osteoarthritis (OA) through the production…”
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Heme oxygenase-1 induction modulates microsomal prostaglandin E synthase-1 expression and prostaglandin E[sub]2 production in osteoarthritic chondrocytes
Published in Biochemical pharmacology (15-06-2009)“…Pro-inflammatory cytokines such as interleukin-1[beta] (IL-1[beta]) may participate in the pathogenesis of cartilage damage in osteoarthritis (OA) through the…”
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Heme oxygenase-1 induction modulates microsomal prostaglandin E synthase-1 expression and prostaglandin E(2) production in osteoarthritic chondrocytes
Published in Biochemical pharmacology (15-06-2009)“…Pro-inflammatory cytokines such as interleukin-1beta (IL-1beta) may participate in the pathogenesis of cartilage damage in osteoarthritis (OA) through the…”
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Different anti-inflammatory effects of extracellular vesicles from adipose-derived mesenchymal stem cell or keratinocyte cell line on osteoarthritic cartilage
Published in Journal of extracellular vesicles (01-01-2018)“…Background: Osteoarthritis (OA) is a joint condition associated with articular cartilage loss, low-grade synovitis and alterations in subchondral bone and…”
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