Search Results - "Castano, Ana"
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"Why Can't I Become a Manager?"-A Systematic Review of Gender Stereotypes and Organizational Discrimination
Published in International journal of environmental research and public health (22-05-2019)“…Women continue to lag behind for accessing managerial positions, partially due to discrimination at work. One of the main roots of such discrimination is…”
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Photodynamic therapy and anti-tumour immunity
Published in Nature reviews. Cancer (01-07-2006)“…Photodynamic therapy (PDT) uses non-toxic photosensitizers and harmless visible light in combination with oxygen to produce cytotoxic reactive oxygen species…”
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Impact of landscape alteration and invasions on pollinators: a meta‐analysis
Published in The Journal of ecology (01-07-2012)“…1. Alterations in land use and biological invasions are two major components of global change that threaten biodiversity. There is high concern about their…”
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Estimating the effect of the reorganization of interactions on the adaptability of species to changing environments
Published in Journal of theoretical biology (21-01-2018)“…•We develop a new theoretical framework to study ecological adaptation to changing environments.•We introduce the concept of adaptation space of a group of…”
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Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide
Published in Science translational medicine (06-01-2021)“…Cell-based therapies are emerging as effective agents against cancer and other diseases. As autonomous "living drugs," these therapies lack precise control…”
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CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity
Published in Nature biotechnology (01-09-2019)“…Chimeric antigen receptor (CAR)-T-cell therapy for solid tumors is limited due to heterogeneous target antigen expression and outgrowth of tumors lacking the…”
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Glycoengineering of chimeric antigen receptor (CAR) T-cells to enforce E-selectin binding
Published in The Journal of biological chemistry (29-11-2019)“…Tissue colonization (homing) by blood-borne cells critically hinges on the ability of the cells to adhere to vascular endothelium with sufficient strength to…”
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Differences and similarities in endothelial and angiogenic profiles of preeclampsia and COVID-19 in pregnancy
Published in American journal of obstetrics and gynecology (01-08-2022)“…COVID-19 presents a spectrum of signs and symptoms in pregnant women that might resemble preeclampsia. Differentiation between severe COVID-19 and preeclampsia…”
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Development, Measurement, and Validation of a Managerial Competency Model in Spain: The PUMAC Questionnaire
Published in European journal of psychological assessment : official organ of the European Association of Psychological Assessment (01-07-2024)“…Modernization of Public Administration (PA), to provide a high-quality service, requires improvements in managerial personnel assessment processes. For this…”
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MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways
Published in Science translational medicine (15-02-2012)“…Scarring of the kidney is a major public health concern, directly promoting loss of kidney function. To understand the role of microRNA (miRNA) in the…”
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Endoscopic Transnasal Trans-Sphenoidal Approach for Pituitary Adenomas: A Comparison to the Microscopic Approach Cohort by Propensity Score Analysis
Published in Neurosurgery (01-03-2020)“…Abstract BACKGROUND Despite some evidence for the adoption of endoscopic transnasal trans-sphenoidal surgery (ETSS) for pituitary adenomas, the advantages of…”
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CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma
Published in Journal for immunotherapy of cancer (14-11-2019)“…Despite remarkable success in the treatment of hematological malignancies, CAR T-cell therapies for solid tumors have floundered, in large part due to local…”
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ApTOLL: A new therapeutic aptamer for cytoprotection and (re)myelination after multiple sclerosis
Published in British journal of pharmacology (01-09-2024)“…Background and Purpose ApTOLL is an aptamer selected to antagonize toll‐like receptor 4 (TLR4), a relevant actor for innate immunity involved in inflammatory…”
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Anti-CD37 chimeric antigen receptor T cells are active against B- and T-cell lymphomas
Published in Blood (04-10-2018)“…Chimeric antigen receptor (CAR) T cells have emerged as a novel form of treatment of patients with B-cell malignancies. In particular, anti-CD19 CAR T-cell…”
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Work characteristics and occupational health: validation and proposal of a shortened version of the Work Design Questionnaire
Published in Anales de psicología (Murcia, Spain) (01-01-2022)“…Interest in the study of work characteristics to explain how an individual's relationship with the work environment can lead to maladaptive responses has taken…”
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Differential protein expression in endothelial cells exposed to serum from patients with acute graft‐vs‐host disease, depending on steroid response
Published in Journal of cellular and molecular medicine (01-05-2023)“…Graft‐versus‐host disease (GVHD) is a complication of allogeneic haematopoietic cell transplantation. Endothelial injury is crucial as pathophysiological…”
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Endothelial Damage, Inflammation and Immunity in Chronic Kidney Disease
Published in Toxins (01-06-2020)“…Chronic kidney disease (CKD) patients have an accelerated atherosclerosis, increased risk of thrombotic-ischemic complications, and excessive mortality rates…”
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Use of chitosan bandage to prevent fatal infections developing from highly contaminated wounds in mice
Published in Biomaterials (01-08-2006)“…HemCon ® bandage is an engineered chitosan acetate preparation used as a hemostatic control dressing, and its chemical structure suggests that it should also…”
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Mechanisms in photodynamic therapy: part one—photosensitizers, photochemistry and cellular localization
Published in Photodiagnosis and photodynamic therapy (01-12-2004)“…The use of non-toxic dyes or photosensitizers (PS) in combination with harmless visible light that is known as photodynamic therapy (PDT) has been known for…”
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A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-Seq
Published in Molecular therapy (02-12-2020)“…T cells engineered to express chimeric antigen receptors (CARs) targeting CD19 have produced impressive outcomes for the treatment of B cell malignancies, but…”
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