Search Results - "Castanha, Priscila M.S."
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Dengue infection in pregnancy and transplacental transfer of anti-dengue antibodies in Northeast, Brazil
Published in Journal of clinical virology (01-05-2014)“…Abstract Background Dengue affects nearly 400 million people annually worldwide and considered one of the most serious health threats in tropical and…”
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Impact of preexisting dengue immunity on Zika virus emergence in a dengue endemic region
Published in Science (American Association for the Advancement of Science) (08-02-2019)“…The clinical outcomes associated with Zika virus (ZIKV) in the Americas have been well documented, but other aspects of the pandemic, such as attack rates and…”
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Severe Acute Respiratory Syndrome Coronavirus 2 Viremia Is Associated With Coronavirus Disease 2019 Severity and Predicts Clinical Outcomes
Published in Clinical infectious diseases (03-05-2022)“…Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA (vRNA) is detected in the bloodstream of some patients with…”
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Dengue Virus–Specific Antibodies Enhance Brazilian Zika Virus Infection
Published in The Journal of infectious diseases (01-03-2017)“…Anti-Flavivirus antibodies are highly cross-reactive and may facilitate Zika virus (ZIKV) infection through the antibody-dependent enhancement (ADE) mechanism…”
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Vaccine development during global epidemics: the Zika experience
Published in The Lancet infectious diseases (01-09-2020)“…Nearly half of the global population lives in areas at risk of Zika transmission, and the chance for future Zika epidemics remains very real. 5 years after the…”
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Zika vaccines: can we solve one problem without creating another one?
Published in The Lancet infectious diseases (01-09-2021)“…Since 2015, the emergence of epidemic Zika virus transmission have been linked to unparalleled reports of serious neurological disorders and devastating birth…”
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Identification and characterization of a nonbiological small-molecular mimic of a Zika virus conformational neutralizing epitope
Published in Proceedings of the National Academy of Sciences - PNAS (21-05-2024)“…Antigenic similarities between Zika virus (ZIKV) and other flaviviruses pose challenges to the development of virus-specific diagnostic tools and effective…”
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Contribution of Coronavirus-Specific Immunoglobulin G Responses to Complement Overactivation in Patients with Severe Coronavirus Disease 2019
Published in The Journal of infectious diseases (13-09-2022)“…Abstract Background Excessive complement activation has been implicated in the pathogenesis of coronavirus disease 2019 (COVID-19), but the mechanisms leading…”
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A Glimmer of Hope: Recent Updates and Future Challenges in Zika Vaccine Development
Published in Viruses (30-11-2020)“…The emergence and rapid spread of Zika virus (ZIKV) on a global scale as well as the establishment of a causal link between Zika infection and congenital…”
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SARS-CoV-2 mRNA Vaccines Induce Greater Complement Activation and Decreased Viremia and Nef Antibodies in Men With HIV-1
Published in The Journal of infectious diseases (12-04-2024)“…Abstract Background Immune dysregulation in people with human immunodeficiency virus-1 (PWH) persists despite potent antiretroviral therapy and, consequently,…”
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Development of antibody biomarkers of long term and recent dengue virus infections
Published in Journal of virological methods (01-07-2018)“…•Anti-dengue NS1 IgG and IG3 are biomarkers of long-term and recent dengue infection.•Other flavivirus anti-NS1 IgG does not cross-react with anti-dengue NS1…”
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Results of a Zika Virus (ZIKV) Immunoglobulin M–Specific Diagnostic Assay Are Highly Correlated With Detection of Neutralizing Anti-ZIKV Antibodies in Neonates With Congenital Disease
Published in The Journal of infectious diseases (15-12-2016)“…Background. Usually, immunoglobulin M (IgM) serologic analysis is not sufficiently specific to confirm Zika virus (ZIKV) infection. However, since IgM does not…”
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Two-year Decay of Zika Virus Neutralizing Antibodies in People Living in an Endemic Region in Brazil
Published in The American journal of tropical medicine and hygiene (13-07-2022)“…It is currently not clear whether humoral immunity to Zika virus (ZIKV) elicited upon natural ZIKV infection is long-lasting. In addition, cross-reactivity of…”
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Perinatal analyses of Zika- and dengue virus-specific neutralizing antibodies: A microcephaly case-control study in an area of high dengue endemicity in Brazil
Published in PLoS neglected tropical diseases (01-03-2019)“…Laboratory confirmation of Zika virus (ZIKV) infection during pregnancy is challenging due to cross-reactivity with dengue virus (DENV) and limited knowledge…”
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Follow-Up Household Serosurvey in Northeast Brazil for Zika Virus: Sexual Contacts of Index Patients Have the Highest Risk for Seropositivity
Published in The Journal of infectious diseases (24-02-2021)“…Abstract Background Zika virus (ZIKV) is a mosquito-borne virus that is also transmitted sexually; however, the epidemiological relevance of ZIKV sexual…”
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Placental Transfer of Dengue Virus (DENV)-Specific Antibodies and Kinetics of DENV Infection-Enhancing Activity in Brazilian Infants
Published in The Journal of infectious diseases (15-07-2016)“…Background. Maternal-fetal transferred dengue virus (DENV)-specific antibodies have been implicated in the immunopathogenesis of dengue during infancy…”
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The Transcriptional and Protein Profile From Human Infected Neuroprogenitor Cells Is Strongly Correlated to Zika Virus Microcephaly Cytokines Phenotype Evidencing a Persistent Inflammation in the CNS
Published in Frontiers in immunology (16-08-2019)“…Zika virus (ZIKV) infection during pregnancy is associated with microcephaly, a congenital malformation resulting from neuroinflammation and direct effects of…”
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Zika virus displacement by a chikungunya outbreak in Recife, Brazil
Published in PLoS neglected tropical diseases (06-11-2017)“…Several arboviruses, including dengue virus (DENV), Zika virus (ZIKV) and chikungunya virus (CHIKV), transmitted by Aedes mosquitoes, circulate in northeast…”
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Early diagnostic indicators of dengue versus other febrile illnesses in Asia and Latin America (IDAMS study): a multicentre, prospective, observational study
Published in The Lancet global health (01-03-2023)“…Improvements in the early diagnosis of dengue are urgently needed, especially in resource-limited settings where the distinction between dengue and other…”
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Persistent detection of Zika virus RNA from an infant with severe microcephaly - a case report
Published in BMC infectious diseases (10-08-2018)“…Zika virus (ZIKV) is a recently emerged arbovirus, which infection during pregnancy is associated with a series of congenital malformations, collectively…”
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