Search Results - "Castaigne, J"

Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep‐2 by Régina, A, Demeule, M, Ché, C, Lavallée, I, Poirier, J, Gabathuler, R, Béliveau, R, Castaigne, J‐P

“…Background and purpose: Paclitaxel is highly efficacious in the treatment of breast, head and neck, non‐small cell lung cancers and ovarian carcinoma. For…”
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Influence of glioma tumour microenvironment on the transport of ANG1005 via low-density lipoprotein receptor-related protein 1 by Bertrand, Y, Currie, J-C, Poirier, J, Demeule, M, Abulrob, A, Fatehi, D, Stanimirovic, D, Sartelet, H, Castaigne, J-P, Béliveau, R

“…Background: ANG1005 consists of three molecules of paclitaxel conjugated via ester bonds to the 19-amino-acid peptide Angiopep-2. The new chemical agent has…”
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UNMET NEED IN RELAPSED/REFRACTORY (R/R) MANTLE CELL LYMPHOMA (MCL) POST‐BRUTON TYROSINE KINASE INHIBITOR (BTKI): A SYSTEMATIC LITERATURE REVIEW AND META‐ANALYSIS by Dreyling, M., Shah, B., Wu, J., Itani, T., Zoratti, M. J., Kanters, S., Wade, S. W., Peng, W., Castaigne, J., Kloos, I., Wang, M.

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Prolonged action of a chimeric interleukin-2 receptor (CD25) monoclonal antibody used in cadaveric renal transplantation by Amlot, P L, Rawlings, E, Fernando, O N, Griffin, P J, Heinrich, G, Schreier, M H, Castaigne, J P, Moore, R, Sweny, P

“…A high affinity chimeric CD25 mAb (chRFT5: SDZ CHI 621) blocking interleukin-2 binding to the interleukin-2 receptor alpha-chain was evaluated in a phase I/II…”
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Pharmacokinetics and tolerability of a novel long-acting glucagon-like peptide-1 analog, CJC-1131, in healthy and diabetic subjects by Tiessen, R G, Castaigne, J P, Dreyfus, J F, Nemansky, M, Kruizinga, H H, van Vliet, A A

“…The safety, tolerability, pharmacokinetics and preliminary pharmacodynamics of single rising doses of a novel GLP-1 analog, CJC-1131, was evaluated. CJC-1131…”
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A CD18‐dependent protein kinase C β‐mediated alternative cell death pathway of activated monocytes by Castaigne, Jean‐Gabriel, Guo, Wenyan, Lévéille, Claire, Charron, Dominique, Al‐Daccak, Reem

“…Activated monocytes become resistant to numerous death stimuli including death receptors. Given that the uncontrolled activation of monocytes/macrophages and…”
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46 REAL-WORLD STUDY TO ASSESS QUALITY OF LIFE, MEDICATION ADHERENCE AND SATISFACTION WITH A LOW-DOSE 7-DAY BUPRENORPHINE PATCH by Dickerson, S., Castaigne, J. G.

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139 POSTER Enhanced drug delivery to brain tumors with a new paclitaxel-peptide conjugate by Bichat, F, Demeule, M, Lawrence, B, Raguin, O, Sourzat, B, Gabathuler, R, P. Castaigne, J, Genne, P

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MHC class II isotype‐specific signaling complex on human B cells by Lévéille, Claire, Castaigne, Jean‐Gabriel, Charron, Dominique, Al‐Daccak, Reem

“…The highly polymorphic human major histocompatibility complex (HLA) class II molecules are acknowledged as signaling receptors although their coupling to…”
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HLA-DR signaling inhibits Fas-mediated apoptosis in A375 melanoma cells by Aoudjit, Fawzi, Guo, Wenyan, Gagnon-Houde, Jean-Vincent, Castaigne, Jean-Gabriel, Alcaide-Loridan, Catherine, Charron, Dominique, Al-Daccak, Reem

“…Although melanocytes are devoid of the human major histocompatibility complex class II (HLA II) molecules, melanomas often display constitutive expression of…”
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Signaling through HLA‐DR induces PKCβ‐dependent B cell death outside rafts by Guo, Wenyan, Castaigne, Jean‐Gabriel, Mooney, Nuala, Charron, Dominique, Al‐Daccak, Reem

“…Signals through HLA‐DR molecules contribute to optimal activation of antigen‐presenting cells (APC) during T cell/APC interactions participating in the…”
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Modeling Covariate-Adjusted Survival for Economic Evaluations in Oncology by Majer, IM, Castaigne, J, Palmer, S, DeCosta, L, Campioni, M

“…OBJECTIVES: Survival data from randomized controlled trials (RCT) is routinely extrapolated for economic evaluations in oncology. Imbalances in prognostic and/…”
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MO3 - Modeling Covariate-Adjusted Survival for Economic Evaluations in Oncology by Majer, IM, Castaigne, J, Palmer, S, DeCosta, L, Campioni, M

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Abstract P6-11-05: ANG4043, a brain-penetrant anti-HER2 mAb increases survival in mice bearing intracranial BT-474 breast tumor cells by Lachowicz, JE, Demeule, M, Regina, A, Houle, E, Tripathy, S, Castaigne, J-P

“…Abstract Background: Treatment options for metastatic brain tumors originating from HER2-positive breast disease are limited due to the inability of most…”
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Pancrease Gastroresistance: In Vitro Evaluation of pH-Determined Dissolution by Lenaerts, C, Beraud, N, Castaigne, J-P

“…In order to avoid inactivation in the stomach, pancreatic enzymes have been prepared as pH-sensitive, enteric-coated microspheres (Pancrease). An in vitro…”
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A quest for meta-learning gains in a physics serious game by Verpoorten, Dominique, Castaigne, Jean-Loup, Westera, Wim, Specht, Marcus

“…This paper describes how a short, repeated and structured opportunity to reflect was integrated in the storyline of a serious game in order to stimulate the…”
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EE146 Cost-Effectiveness of Axicabtagene Ciloleucel Versus Other CAR T-Cell Therapies in the Treatment of Diffuse Large B-Cell Lymphoma in France by Brighton, N, Zang, A, Castaigne, JG

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EE438 Assessing the Cost-Effectiveness of Axicabtagene Ciloleucel Compared With Other CAR T-Cell Therapies in the Treatment of Diffuse Large B-Cell Lymphoma in the UK by Brighton, N, Lovato, E, Castaigne, JG

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Efficacy of Pancrease: Crossover Comparative Study versus Eurobiol in Cystic Fibrosis by Chazalette, J-P, Dain, M P, Castaigne, J-P

“…An open crossover study in patients with documented cystic fibrosis (CF) compared the efficacy and acceptability of Pancrease (Cilag, PC), consisting of…”
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Influence of glioma tumour microenvironment on the transport of ANG1005 via low-density lipoprotein receptor-related protein I by BERTRAND, Y, CURRIE, J.-C, POIRIER, J. J, DEMEULE, M, ABULROB, A, FATEHI, D, STANIMIROVIC, D, SARTELET, H, CASTAIGNE, J.-P, BELIVEAU, R

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