Search Results - "Casson, Alan G"
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Body mass index in relation to oesophageal and oesophagogastric junction adenocarcinomas: a pooled analysis from the International BEACON Consortium
Published in International journal of epidemiology (01-12-2012)“…Previous studies suggest an association between obesity and oesophageal (OA) and oesophagogastric junction adenocarcinomas (OGJA). However, these studies have…”
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MicroRNA Expression in Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus: Associations with Survival
Published in Clinical cancer research (01-10-2009)“…Purpose: The dismal outcome of esophageal cancer patients highlights the need for novel prognostic biomarkers, such as microRNAs (miRNA). Although recent…”
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3
Gastroesophageal reflux in relation to adenocarcinomas of the esophagus: a pooled analysis from the Barrett's and Esophageal Adenocarcinoma Consortium (BEACON)
Published in PloS one (30-07-2014)“…Previous studies have evidenced an association between gastroesophageal reflux and esophageal adenocarcinoma (EA). It is unknown to what extent these…”
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Cigarette Smoking and Adenocarcinomas of the Esophagus and Esophagogastric Junction: A Pooled Analysis From the International BEACON Consortium
Published in JNCI : Journal of the National Cancer Institute (08-09-2010)“…Background Previous studies that showed an association between smoking and adenocarcinomas of the esophagus and esophagogastric junction were limited in their…”
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Identification and characterization of stemlike cells in human esophageal adenocarcinoma and normal epithelial cell lines
Published in The Journal of thoracic and cardiovascular surgery (01-11-2012)“…Objective Recent studies have suggested that human solid tumors may contain subpopulations of cancer stem cells with the capacity for self-renewal and the…”
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Inflammatory and MicroRNA Gene Expression as Prognostic Classifier of Barrett's-Associated Esophageal Adenocarcinoma
Published in Clinical cancer research (01-12-2010)“…Esophageal cancer is one of the most aggressive and deadly forms of cancer; highlighting the need to identify biomarkers for early detection and prognostic…”
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Prognostic value of p53 mutations in oesophageal adenocarcinoma: final results of a 15-year prospective study
Published in European journal of cardio-thoracic surgery (01-06-2010)“…Objective: This study evaluates the clinical significance of p53 mutations in oesophageal adenocarcinoma (EADC). Methods: Between February 1991 and February…”
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Validation of the functional assessment of cancer therapy esophageal cancer subscale
Published in Cancer (15-08-2006)“…BACKGROUND. To develop and validate a quality of life subscale for patients with esophageal cancer to be used with the Functional Assessment of Cancer…”
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MiRNA-Related SNPs and Risk of Esophageal Adenocarcinoma and Barrett's Esophagus: Post Genome-Wide Association Analysis in the BEACON Consortium
Published in PloS one (2015)“…Incidence of esophageal adenocarcinoma (EA) has increased substantially in recent decades. Multiple risk factors have been identified for EA and its precursor,…”
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10
Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas
Published in PloS one (01-07-2014)“…Although implicated in the pathogenesis of several chronic inflammatory disorders and hematologic malignancies, telomerase mutations have not been thoroughly…”
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Molecular Evolution of the Metaplasia-Dysplasia-Adenocarcinoma Sequence in the Esophagus
Published in The American journal of pathology (01-04-1999)“…The incidence of adenocarcinoma of the esophagus has been increasing in developing countries over the last three decades and probably reflects a genuine…”
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Polymorphisms in Genes of Relevance for Oestrogen and Oxytocin Pathways and Risk of Barrett's Oesophagus and Oesophageal Adenocarcinoma: A Pooled Analysis from the BEACON Consortium
Published in PloS one (2015)“…The strong male predominance in oesophageal adenocarcinoma (OAC) and Barrett's oesophagus (BO) continues to puzzle. Hormonal influence, e.g. oestrogen or…”
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13
Polymorphisms in DNA repair genes in the molecular pathogenesis of esophageal (Barrett) adenocarcinoma
Published in Carcinogenesis (New York) (01-09-2005)“…To test the hypothesis that aberrations of DNA repair contribute to susceptibility for the progression of gastroesophageal reflux disease (GERD) into Barrett…”
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14
Waiting for scheduled surgery: A complex patient experience
Published in Journal of health psychology (01-03-2017)“…The aim of this study was to understand experiences of wait time among patients awaiting scheduled orthopaedic or cardiac surgery. Using a qualitative…”
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Regulation of CDX2 expression in esophageal adenocarcinoma
Published in Molecular carcinogenesis (01-10-2009)“…Reflux of acidic gastric contents and bile acids into the lower esophagus has been identified to have a central role in esophageal malignancy and is reported…”
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Inducible nitric oxide synthase, nitrotyrosine and p53 mutations in the molecular pathogenesis of Barrett's esophagus and esophageal adenocarcinoma
Published in Molecular carcinogenesis (01-04-2008)“…Nitric oxide (NO) has been implicated as a potential causative factor for endogenous p53 mutations in gastrointestinal malignancy. To investigate the role of…”
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Basic Fibroblast Growth Factor (FGF-2) Overexpression Is a Risk Factor for Esophageal Cancer Recurrence and Reduced Survival, which Is Ameliorated by Coexpression of the FGF-2 Antisense Gene
Published in Clinical cancer research (01-11-2005)“…Purpose: The basic fibroblast growth factor ( FGF-2 ) gene is bidirectionally transcribed to generate overlapping sense and antisense (FGF-AS) mRNAs. FGF-AS…”
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Photofrin PDT for early stage esophageal cancer: A new standard of care?
Published in Photodiagnosis and photodynamic therapy (01-09-2009)Get full text
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Loss of imprinting and abnormal expression of the insulin-like growth factor 2 gene in gastric cancer
Published in Molecular carcinogenesis (01-05-2011)“…This study examined the frequency of loss of imprinting (LOI) and expression of the insulin‐like growth factor 2 (IGF2) gene, and their relationship to…”
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Waiting for surgery from the patient perspective
Published in Psychology Research and Behavior Management (01-01-2009)“…The aim of this study was to perform a systematic review of the impact of waiting for elective surgery from the patient perspective, with a focus on maximum…”
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