Search Results - "Cassidy, Kevin C."
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ProteinVR: Web-based molecular visualization in virtual reality
Published in PLoS computational biology (01-03-2020)“…Protein structure determines biological function. Accurately conceptualizing 3D protein/ligand structures is thus vital to scientific research and education…”
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Comparative analysis of the LARP1 C-terminal DM15 region through Coelomate evolution
Published in PloS one (27-08-2024)“…TOR (target of rapamycin), a ubiquitous protein kinase central to cellular homeostasis maintenance, fundamentally regulates ribosome biogenesis in part by its…”
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Capturing the Mechanism Underlying TOP mRNA Binding to LARP1
Published in Structure (London) (03-12-2019)“…The RNA-binding protein La-related protein 1 (LARP1) plays a central role in ribosome biosynthesis. Its C-terminal DM15 region binds the 7-methylguanosine…”
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Webina: an open-source library and web app that runs AutoDock Vina entirely in the web browser
Published in Bioinformatics (15-08-2020)“…Abstract Motivation Molecular docking is a computational technique for predicting how a small molecule might bind a macromolecular target. Among docking…”
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Secondary-Structure Changes Impact LARP1/mRNA Binding: Simulations and Experiments Suggest New Avenues for Anti-Cancer Drug Discovery
Published in Biophysical journal (07-02-2020)Get full text
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Capturing the Mechanism Underlying Top-Binding to the LARP1 DM15 Region
Published in Biophysical journal (15-02-2019)Get full text
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Capturing the Mechanism Underlying TOP mRNA Binding to LARP1
Published in Structure (London) (01-12-2019)Get full text
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Investigating the Dynamics of LARP1 DM15: A Stalwart of Ribosome Biogenesis Regulation
Published 01-01-2021“…Eukaryotic cells regulate the synthesis of proteins based on environmental conditions such as nutrient abundance or stress. Ribosome biogenesis is a key node…”
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Dissertation