Search Results - "Cassels, Frederick J."

Special Issue on Enterotoxigenic Escherichia coli (ETEC) Vaccines: ETEC Infection and Vaccine-Mediated Immunity by Cassels, Frederick J, Khalil, Ibrahim, Bourgeois, A Louis, Walker, Richard I

“…Enterotoxigenic (ETEC) is the most prevalent bacterial pathogen causing young children to suffer acute watery diarrhea in Low- and Middle-Income Countries…”
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Evolutionary and Functional Relationships of Colonization Factor Antigen I and Other Class 5 Adhesive Fimbriae of Enterotoxigenic Escherichia coli by ANANTHA, Ravi P, MCVEIGH, Annette L, LEE, Lanfong H, AGNEW, Mary K, CASSELS, Frederick J, SCOTT, Daniel A, WHITTAM, Thomas S, SAVARINO, Stephen J

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Safety and Immunogenicity of a Prototype Enterotoxigenic Escherichia coli Vaccine Administered Transcutaneously by GÜERENA-BURGUENO, Fernando, HALL, Eric R, TAYLOR, David N, CASSELS, Frederick J, SCOTT, Daniel A, WOLF, Marcia K, ROBERTS, Zachary J, NESTEROVA, Galina V, ALVING, Carl R, GLENN, Gregory M

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Mucosal and Systemic Immune Responses in Patients with Diarrhea Due to CS6-Expressing Enterotoxigenic Escherichia coli by Qadri, Firdausi, Ahmed, Tanvir, Ahmed, Firoz, Bhuiyan, M. Saruar, Mostofa, Mohammad Golam, Cassels, Frederick J, Helander, Anna, Svennerholm, Ann-Mari

“…Colonization factor CS6 expressed by enterotoxigenic Escherichia coli (ETEC) is a nonfimbrial polymeric protein. A substantial proportion of ETEC strains…”
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Randomized Clinical Trial Assessing the Safety and Immunogenicity of Oral Microencapsulated Enterotoxigenic Escherichia coli Surface Antigen 6 with or without Heat-Labile Enterotoxin with Mutation R192G by Lapa, Joyce A, Sincock, Stephanie A, Ananthakrishnan, Madhumita, Porter, Chad K, Cassels, Frederick J, Brinkley, Carl, Hall, Eric R, van Hamont, John, Gramling, Joseph D, Carpenter, Colleen M, Baqar, S, Tribble, David R

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Pathogenicity and Immune Response Measured in Mice following Intranasal Challenge with Enterotoxigenic Escherichia coli Strains H10407 and B7A by BYRD, Wyatt, MOG, Steven R, CASSELS, Frederick J

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Choice of adjuvant and antigen composition alters the immunogenic profile of a SARS-CoV-2 subunit vaccine by Lykins, William R., Pollet, Jeroen, White, Jessica A., Keegan, Brian, Versteeg, Leroy, Strych, Ulrich, Chen, Wen-Hsiang, Mohamath, Raodoh, Ramer-Denisoff, Gabi, Reed, Sierra, Beaver, Samuel, Gerhardt, Alana, Voigt, Emily A., Tomai, Mark A., Sitrin, Robert, Choy, Robert K. M., Cassels, Frederick J., Hotez, Peter J., Bottazzi, Maria Elena, Fox, Christopher B.

“…Introduction: Since their introduction, adjuvanted recombinant subunit vaccines against COVID-19 have played a pivotal role in protecting global populations…”
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Structural Characterization of the Pseudomonas aeruginosa 1244 Pilin Glycan by Castric, Peter, Cassels, Frederick J., Carlson, Russell W.

“…An antigenic similarity between lipopolysaccharide (LPS) and glycosylated pilin of Pseudomonas aeruginosa 1244 was noted. We purified a glycan-containing…”
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Intranasal immunization of BALB/c mice with enterotoxigenic Escherichia coli colonization factor CS6 encapsulated in biodegradable poly( dl-lactide- co-glycolide) microspheres by Byrd, Wyatt, Cassels, Frederick J.

“…Mice were intranasally administered enterotoxigenic Escherichia coli colonization factor CS6 encapsulated in poly( dl-lactide- co-glycolide) microspheres…”
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Oral immunization of adult volunteers with microencapsulated enterotoxigenic Escherichia coli (ETEC) CS6 antigen by Katz, David E, DeLorimier, Arthur J, Wolf, Marcia K, Hall, Eric R, Cassels, Frederick J, van Hamont, John E, Newcomer, Rhonda L, Davachi, Mitra A, Taylor, David N, McQueen, Charles E

“…As a step in the development of an oral vaccine against ETEC, we evaluated the safety and immunogenicity of CS6, a polymeric protein commonly found on the…”
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Escherichia coli Strain RDEC-1 AF/R1 Endogenous Fimbrial Glycoconjugate Receptor Molecules in Rabbit Small Intestine by RYU, Hyoik, KIM, Young S, GRANGE, Philippe A, CASSELS, Frederick J

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Microencapsulated subunit vaccine approach to enterotoxigenic Escherichia coli and other mucosal pathogens by Byrd, Wyatt, de Lorimier, Arthur, Zheng, Zi-Rong, Cassels, Frederick J.

“…Infections of the intestinal, urogenital, and respiratory tracts are serious health problems worldwide from both a morbidity and mortality perspective. Mucosal…”
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The encapsulation of enterotoxigenic Escherichia coli colonization factor CS3 in biodegradable microspheres enhances the murine antibody response following intranasal administration by Byrd, Wyatt, Cassels, Frederick J

“…1 Department of Enteric Infections, Walter Reed Army Institute of Research, Silver Spring, MD 20910-7500, USA 2 18929 Fountain Hills Drive, Germantown, MD…”
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Recruitment of murine neutrophils in vivo through endogenous sialidase activity by Cross, Alan S, Sakarya, Serhan, Rifat, Salahaldin, Held, Thomas K, Drysdale, Beth-Ellen, Grange, Philippe A, Cassels, Frederick J, Wang, Lai-Xi, Stamatos, Nicholas, Farese, Ann, Casey, Daniel, Powell, Jan, Bhattacharjee, Apurba K, Kleinberg, Michael, Goldblum, Simeon E

“…Upon activation with various noncytokine stimuli, polymorphonuclear leukocytes (PMNs) mobilize intracellular sialidase to the plasma membrane, where the…”
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Mucosal immunization of BALB/c mice using enterotoxigenic Escherichia coli colonization factors CFA/I and CS6 administered with and without a mutant heat-labile enterotoxin by Byrd, Wyatt, Cassels, Frederick J

“…Mice (BALB/c) were intranasally (IN) and intragastrically (IG) administered the ETEC colonization factors (CF), CFA/I and CS6, with and without the R192G…”
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The New World primate, Aotus nancymae, as a model for examining the immunogenicity of a prototype enterotoxigenic Escherichia coli subunit vaccine by Jones, Franca R., Hall, Eric R., Tribble, David, Savarino, Stephen J., Cassels, Frederick J., Porter, Chad, Meza, Rina, Nunez, Gladys, Espinoza, Nereyda, Salazar, Milagros, Luckett, Rickey, Scott, Daniel

“…The colonization factors (CF) of enterotoxigenic Escherichia coli (ETEC) are being targeted for inclusion in a multi-subunit ETEC vaccine. This study was…”
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Identification and Characterization of Hydrophobic Escherichia coli Virulence Proteins by Liquid Chromatography–Electrospray Ionization Mass Spectrometry by Hess, Sonja, Cassels, Frederick J., Pannell, Lewis K.

“…Virulence of enterotoxicogenic Escherichia coli is mediated by rodlike, rigid, highly hydrophobic proteins designated fimbriae or colonization factors (CFs)…”
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Murine antibody response to intranasally administered enterotoxigenic Escherichia coli colonization factor CS6 by de Lorimier, Arthur J, Byrd, Wyatt, Hall, Eric R, Vaughan, William M, Tang, Douglas, Roberts, Zachary J, McQueen, Charles E, Cassels, Frederick J

“…Enterotoxigenic Escherichia coli (ETEC) is the most common cause of bacterial diarrhea worldwide and is an important cause of infant morbidity and mortality in…”
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Long-term systemic and mucosal antibody responses measured in BALB/c mice following intranasal challenge with viable enterotoxigenic Escherichia coli by Byrd, Wyatt, Cassels, Frederick J.

“…Abstract The immunogenicity induced in BALB/c mice following intranasal challenge with a viable nonlethal dose (1.2 × 108 CFU) of enterotoxigenic Escherichia…”
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The CS6 colonization factor of human enterotoxigenic Escherichia coli contains two heterologous major subunits by Wolf, Marcia K, de Haan, Louise A.M, Cassels, Frederick J, Willshaw, Geraldine A, Warren, Richard, Boedeker, Edgar C, Gaastra, Wim

“…The genes encoding the CS6 colonization factor were cloned from two human enterotoxigenic Escherichia coli strains of different serotypes. The DNA sequences…”
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