Search Results - "Cassady, Robin L"
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Antigen Sampling CSF1R -Expressing Epithelial Cells Are the Functional Equivalents of Mammalian M Cells in the Avian Follicle-Associated Epithelium
Published in Frontiers in immunology (22-10-2019)“…The follicle-associated epithelium (FAE) is a specialized structure that samples luminal antigens and transports them into mucosa-associated lymphoid tissues…”
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Selective Induction of Expression of a Ligand for the NKG2D Receptor by Proteasome Inhibitors
Published in Cancer research (Chicago, Ill.) (01-03-2008)“…The interaction of the activating receptor NKG2D with its ligands plays an important role in immunosurveillance of tumors and infectious pathogens, but…”
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NKG2D is a Key Receptor for Recognition of Bladder Cancer Cells by IL-2-Activated NK Cells and BCG Promotes NK Cell Activation
Published in Frontiers in immunology (08-06-2015)“…Intravesical instillation of bacillus Calmette-Guérin (BCG) is used to treat superficial bladder cancer, either papillary tumors (after transurethral…”
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Increased negative selection impairs neonatal B cell repertoire but does not directly lead to generation of disease-associated IgM auto-antibodies
Published in International immunology (01-05-2006)“…To determine if increased negative B cell selection, due to lowered signaling threshold of responsiveness to a ligand as a result of SHP-1 deficiency, during…”
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The Nasal Epithelium as a Factory for Systemic Protein Delivery
Published in Molecular therapy (01-02-2002)“…We have previously shown that recombinant Sendai virus (SeV) produces efficient in vivo airway epithelial gene transfer. The ability to produce therapeutic…”
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Interaction of Bovine Lymphocytes with Products of Shiga Toxin-Producing Escherichia coli
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…Shiga toxin-producing Escherichia coli (STEC) produce a number of virulence factors that interfere with lymphocyte functions, including mitogen- and…”
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Direct Manipulation of T Lymphocytes by Proteins of Gastrointestinal Bacterial Pathogens
Published in Infection and immunity (01-05-2018)“…Gastrointestinal bacterial infection represents a significant threat to human health, as well as a burden on food animal production and welfare. Although there…”
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Activity of Lymphostatin, A Lymphocyte Inhibitory Virulence Factor of Pathogenic Escherichia coli, is Dependent on a Cysteine Protease Motif
Published in Journal of molecular biology (17-09-2021)“…[Display omitted] •LifA shares a cysteine protease motif with bacterial toxins and secreted effectors.•C1480A substituted LifA has reduced inhibitory activity…”
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BMC Medicine celebrates its 5th anniversary
Published in BMC medicine (15-01-2009)“…In November 2008, BMC Medicine passed the landmark of its first 5 years of publishing. When we launched the journal with the aim of publishing high quality…”
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The Differential Regulation of Lck Kinase Phosphorylation Sites by CD45 Is Critical for T Cell Receptor Signaling Responses
Published in Immunity (Cambridge, Mass.) (01-09-2007)“…The molecular mechanisms whereby the CD45 tyrosine phosphatase (PTPase) regulates T cell receptor (TCR) signaling responses remain to be elucidated. To…”
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A vision of the future for BMC Medicine: serving science, medicine and authors
Published in BMC medicine (07-10-2009)“…In June 2009, BMC Medicine received its first official impact factor of 3.28 from Thomson Reuters. In recognition of this landmark event, the BMC Medicine…”
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Inhibition of Antigen-Specific and Nonspecific Stimulation of Bovine T and B Cells by Lymphostatin from Attaching and Effacing Escherichia coli
Published in Infection and immunity (01-02-2017)“…Enterohemorrhagic Escherichia coli (EHEC) and enteropathogenic E. coli (EPEC) are enteric bacterial pathogens of worldwide importance. Most EPEC and non-O157…”
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Biophysical Characterization and Activity of Lymphostatin, a Multifunctional Virulence Factor of Attaching and Effacing Escherichia coli
Published in The Journal of biological chemistry (11-03-2016)“…Attaching and effacing Escherichia coli cause diarrhea and typically produce lymphostatin (LifA), an inhibitor of mitogen-activated proliferation of…”
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Superoxide dismutase SodB is a protective antigen against Campylobacter jejuni colonisation in chickens
Published in Vaccine (17-11-2015)“…Highlights • We tested SodB in chickens as an anti- Campylobacter recombinant subunit vaccine. • It induced a statistically significant reduction in caecal C…”
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Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes
Published in Nature cell biology (01-08-2005)“…Phosphatidylserine (PS) exposure is normally associated with apoptosis and the removal of dying cells. We observed that PS is exposed constitutively at high…”
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Either of the CD45RB and CD45RO Isoforms Are Effective in Restoring T Cell, But Not B Cell, Development and Function in CD45-Null Mice
Published in The Journal of immunology (1950) (15-08-2003)“…The protein tyrosine phosphatase CD45 is expressed as a series of isoforms whose tissue and differentiation stage specificity is broadly conserved in…”
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CD45 isoforms in T cell signalling and development
Published in Immunology letters (29-03-2004)“…The CD45 phosphotyrosine phosphatase is expressed on T cells as multiple isoforms due to alternative splicing. The panoply of isoforms expressed is tightly…”
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BMC Medicine celebrates its 5thanniversary
Published in BMC medicine (15-01-2009)Get full text
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BMC Medicine celebrates its 5.sup.th .sup.anniversary
Published in BMC medicine (15-01-2009)Get full text
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Article: The Differential Regulation of Lck Kinase Phosphorylation Sites by CD45 Is Critical for T Cell Receptor Signaling Responses
Published in Immunity (Cambridge, Mass.) (01-09-2007)“…The molecular mechanisms whereby the CD45 tyrosine phosphatase (PTPase) regulates T cell receptor (TCR) signaling responses remain to be elucidated. To…”
Get full text
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