Search Results - "Caspers, Martien P M"
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Deep sequencing analyses of low density microbial communities: working at the boundary of accurate microbiota detection
Published in PloS one (06-03-2012)“…Accurate analyses of microbiota composition of low-density communities (10(3)-10(4) bacteria/sample) can be challenging. Background DNA from chemicals and…”
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Development of a novel non-invasive biomarker panel for hepatic fibrosis in MASLD
Published in Nature communications (29-05-2024)“…Accurate non-invasive biomarkers to diagnose metabolic dysfunction-associated steatotic liver disease (MASLD)-related fibrosis are urgently needed. This study…”
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Beneficial effects of elafibranor on NASH in E3L.CETP mice and differences between mice and men
Published in Scientific reports (03-03-2021)“…Non-alcoholic steatohepatitis (NASH) is the most rapidly growing liver disease that is nevertheless without approved pharmacological treatment. Despite great…”
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Semaglutide Has Beneficial Effects on Non-Alcoholic Steatohepatitis in Ldlr-/-.Leiden Mice
Published in International journal of molecular sciences (09-05-2023)“…Semaglutide, a glucagon-like peptide-1 receptor agonist, is an antidiabetic medication that has recently been approved for the treatment of obesity as well…”
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Atorvastatin Attenuates Diet-Induced Non-Alcoholic Steatohepatitis in APOE3-Leiden Mice by Reducing Hepatic Inflammation
Published in International journal of molecular sciences (25-04-2023)“…Patients with metabolic syndrome are often prescribed statins to prevent the development of cardiovascular disease. Conversely, data on their effects on…”
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6
Insertion sequence-driven diversification creates a globally dispersed emerging multiresistant subspecies of E. faecium
Published in PLoS pathogens (01-01-2007)“…Enterococcus faecium, an ubiquous colonizer of humans and animals, has evolved in the last 15 years from an avirulent commensal to the third most frequently…”
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Genomic diversity within the Enterobacter cloacae complex
Published in PloS one (21-08-2008)“…Isolates of the Enterobacter cloacae complex have been increasingly isolated as nosocomial pathogens, but phenotypic identification of the E. cloacae complex…”
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Molecular assessment of bacterial vaginosis by Lactobacillus abundance and species diversity
Published in BMC infectious diseases (23-04-2016)“…To date, women are most often diagnosed with bacterial vaginosis (BV) using microscopy based Nugent scoring or Amsel criteria. However, the accuracy is less…”
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A Novel Personalized Systems Nutrition Program Improves Dietary Patterns, Lifestyle Behaviors and Health-Related Outcomes: Results from the Habit Study
Published in Nutrients (22-05-2021)“…Personalized nutrition may be more effective in changing lifestyle behaviors compared to population-based guidelines. This single-arm exploratory study…”
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10
Abiotic and Microbiotic Factors Controlling Biofilm Formation by Thermophilic Sporeformers
Published in Applied and Environmental Microbiology (01-09-2013)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Evidence for sex-specific intramuscular changes associated to physical weakness in adults older than 75 years
Published in Biology of sex differences (10-07-2023)“…Physical weakness is a key component of frailty, and is highly prevalent in older adults. While females have a higher prevalence and earlier onset, sex…”
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Identification of resistance and virulence factors in an epidemic Enterobacter hormaechei outbreak strain
Published in Microbiology (Society for General Microbiology) (01-05-2009)“…1 Department of Medical Microbiology, University Medical Centre Utrecht, Utrecht, The Netherlands 2 TNO Department of Microbiology, Zeist, The Netherlands…”
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Same Exposure but Two Radically Different Responses to Antibiotics: Resilience of the Salivary Microbiome versus Long-Term Microbial Shifts in Feces
Published in mBio (10-11-2015)“…Due to the spread of resistance, antibiotic exposure receives increasing attention. Ecological consequences for the different niches of individual microbiomes…”
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Transcriptional activity around bacterial cell death reveals molecular biomarkers for cell viability
Published in BMC genomics (06-12-2008)“…In bacteriology, the ability to grow in selective media and to form colonies on nutrient agar plates is routinely used as a retrospective criterion for the…”
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15
Unraveling the Transcriptional Dynamics of NASH Pathogenesis Affecting Atherosclerosis
Published in International journal of molecular sciences (26-07-2022)“…The prevalence of non-alcoholic steatohepatitis (NASH) is rapidly increasing and associated with cardiovascular disease (CVD), the major cause of mortality in…”
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Integrating text mining with network models for successful target identification: in vitro validation in MASH-induced liver fibrosis
Published in Frontiers in pharmacology (27-09-2024)“…An target discovery pipeline was developed by including a directional and weighted molecular disease network for metabolic dysfunction-associated…”
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Corrigendum: Ldlr-/-.Leiden mice develop neurodegeneration, age-dependent astrogliosis and obesity-induced changes in microglia immunophenotype which are partly reversed by complement component 5 neutralizing antibody
Published in Frontiers in cellular neuroscience (08-08-2023)“…[This corrects the article DOI: 10.3389/fncel.2023.1205261.]…”
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Ldlr-/-.Leiden mice develop neurodegeneration, age-dependent astrogliosis and obesity-induced changes in microglia immunophenotype which are partly reversed by complement component 5 neutralizing antibody
Published in Frontiers in cellular neuroscience (29-06-2023)“…Obesity has been linked to vascular dysfunction, cognitive impairment and neurodegenerative diseases. However, experimental models that recapitulate brain…”
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Butyrate Protects against Diet-Induced NASH and Liver Fibrosis and Suppresses Specific Non-Canonical TGF-β Signaling Pathways in Human Hepatic Stellate Cells
Published in Biomedicines (20-12-2021)“…In obesity-associated non-alcoholic steatohepatitis (NASH), persistent hepatocellular damage and inflammation are key drivers of fibrosis, which is the main…”
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A mixed-species microarray for identification of food spoilage bacilli
Published in Food microbiology (01-04-2011)“…Failure of food preservation is frequently caused by thermostable spores of members of the Bacillaceae family, which show a wide spectrum of resistance to…”
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