Search Results - "Casorzo, L"
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Dual MET/EGFR therapy leads to complete response and resistance prevention in a MET-amplified gastroesophageal xenopatient cohort
Published in Oncogene (02-03-2017)“…Amplification of the MET oncogene occurs in 2–4% of gastroesophageal cancers and defines a small and aggressive subset of tumors. Although in vitro studies…”
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312 MET and KRAS gene amplification mediates acquired resistance to MET tyrosine kinase inhibitors
Published in European journal of cancer supplements (2010)Get full text
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3
40P A peculiar chromosome 17 copy number profile stratifies HER2-low breast carcinomas
Published in ESMO open (01-05-2024)Get full text
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Integrative genomic and transcriptomic analyses illuminate the ontology of HER2-low breast carcinomas
Published in Genome medicine (29-08-2022)“…The "HER2-low" nomenclature identifies breast carcinomas (BCs) displaying a HER2 score of 1+/2+ in immunohistochemistry and lacking ERBB2 amplification…”
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5
Leukemia-Derived Immature Dendritic Cells Differentiate into Functionally Competent Mature Dendritic Cells That Efficiently Stimulate T Cell Responses
Published in The Journal of immunology (1950) (15-08-2004)“…Primary acute myeloid leukemia cells can be induced to differentiate into dendritic cells (DC). In the presence of GM-CSF, TNF-alpha, and/or IL-4,…”
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6
HER2 gene-amplified breast cancers with monosomy of chromosome 17 are poorly responsive to trastuzumab-based treatment
Published in Oncology reports (01-02-2005)“…Although HER2 gene status determines the eligibility of breast cancer patients to trastuzumab therapy, only a fraction of HER2 gene-amplified cancers are…”
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7
Fluorescence in situ hybridization (FISH) evaluation of chromosomes 6, 7, 9 and 10 throughout human melanocytic tumorigenesis
Published in Melanoma research (01-06-2005)“…Loss of the 9p21 region, 6q and 10q and gain of chromosome 7 are the most frequent chromosomal abnormalities found in human melanomas, but very few cytogenetic…”
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8
HER2 testing in gastric cancer: molecular morphology and storage time-related changes in archival samples
Published in International journal of oncology (01-11-2003)“…Seventy-two archival specimens of advanced gastric adenocarcinoma were analyzed by fluorescence in situ hybridization and immunohistochemistry for HER2 gene…”
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Deletions of 17p are associated with transition from early to advanced colorectal cancer
Published in Cancer genetics and cytogenetics (01-11-2003)“…Several chromosome defects parallel morphologic evolution in colorectal tumor progression. Allelic losses in the short arm of chromosome 17, the majority…”
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10
Cytogenetic findings in a case of dedifferentiated chondrosarcoma
Published in Cancer genetics and cytogenetics (01-07-2003)“…Cytogenetic analysis of a case of dedifferentiated chondrosarcoma with a malignant fibrous histiocytoma (MFH) component revealed a near-triploid karyotype with…”
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Gastrointestinal Stromal Tumor, Uncommitted Type, with Monosomies 14 and 22 as the Only Chromosomal Abnormalities
Published in Cancer genetics and cytogenetics (15-04-1998)“…Karyotypic analysis of a gastric stromal tumor with the histologic and immunohistochemical features of a malignant, uncommitted lesion revealed clonal…”
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Extraskeletal Ewing's tumor with translocation t(11;22) in a patient with Down syndrome
Published in Cancer genetics and cytogenetics (01-01-1989)“…A case of a small cell malignant tumor that occurred in the soft tissues of a 16-year-old boy with Down syndrome (47,XY,+21) is reported. The histologic and…”
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