Search Results - "Casoni, G P"

Infection and immunity on a chip: a compartmentalised microfluidic platform to monitor immune cell behaviour in real time by Gopalakrishnan, N, Hannam, R, Casoni, G P, Barriet, D, Ribe, J M, Haug, M, Halaas, Ø

“…Cells respond to their environments and self-organise into multicellular assemblies with dedicated functions. The migratory and homing response of cells to…”
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PB2271: GERMLINE LOSS OF RHOG IDENTIFIES ITS ROLE AS AN ESSENTIAL REGULATOR OF HUMAN LYMPHOCYTE CYTOTOXICITY by Kalinichenko, A., Casoni, G. P., Dupré, L., Trotta, L., Huemer, J., Galgano, D., German, Y., Haladik, B., Pazmandi, J., Thian, M., Yüce Petronczki, Ö., Chiang, S. C., Taskinen, M., Hekkala, A., Kauppila, S., Lindgren, O., Tapiainen, T., Kraakman, M. J., Vettenranta, K., Lomakin, A. J., Saarela, J., Seppänen, M. R., Bryceson, Y. T., Boztug, K.

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Viral host range factors antagonize pathogenic SAMD9 and SAMD9L variants by Gahr, Stine, Perinetti Casoni, Giovanna, Falk-Paulsen, Maren, Maschkowitz, Gregor, Bryceson, Yenan T., Voss, Matthias

“…SAMD9 and SAMD9L encode homologous interferon-induced genes that can inhibit cellular translation as well as proliferation and can restrict viral replication…”
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Human skin-resident CD8+ T cells require RUNX2 and RUNX3 for induction of cytotoxicity and expression of the integrin CD49a by Zitti, Beatrice, Hoffer, Elena, Zheng, Wenning, Pandey, Ram Vinay, Schlums, Heinrich, Perinetti Casoni, Giovanna, Fusi, Irene, Nguyen, Lien, Kärner, Jaanika, Kokkinou, Efthymia, Carrasco, Anna, Gahm, Jessica, Ehrström, Marcus, Happaniemi, Staffan, Keita, Åsa V., Hedin, Charlotte R.H., Mjösberg, Jenny, Eidsmo, Liv, Bryceson, Yenan T.

“…The integrin CD49a marks highly cytotoxic epidermal-tissue-resident memory (TRM) cells, but their differentiation from circulating populations remains poorly…”
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RhoG deficiency abrogates cytotoxicity of human lymphocytes and causes hemophagocytic lymphohistiocytosis by Kalinichenko, Artem, Perinetti Casoni, Giovanna, Dupré, Loïc, Trotta, Luca, Huemer, Jakob, Galgano, Donatella, German, Yolla, Haladik, Ben, Pazmandi, Julia, Thian, Marini, Yüce Petronczki, Özlem, Chiang, Samuel C., Taskinen, Mervi, Hekkala, Anne, Kauppila, Saila, Lindgren, Outi, Tapiainen, Terhi, Kraakman, Michael J., Vettenranta, Kim, Lomakin, Alexis J., Saarela, Janna, Seppänen, Mikko R.J., Bryceson, Yenan T., Boztug, Kaan

“…Exocytosis of cytotoxic granules (CG) by lymphocytes is required for the elimination of infected and malignant cells. Impairments in this process underly a…”
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SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency by Schmied, Laurent, Luu, Thuy T, Søndergaard, Jonas N, Hald, Sophia H, Meinke, Stephan, Mohammad, Dara K, Singh, Sunitha B, Mayer, Corinna, Perinetti Casoni, Giovanna, Chrobok, Michael, Schlums, Heinrich, Rota, Giorgia, Truong, Hieu M, Westerberg, Lisa S, Guarda, Greta, Alici, Evren, Wagner, Arnika K, Kadri, Nadir, Bryceson, Yenan T, Saeed, Mezida B, Höglund, Petter

“…Natural killer (NK) cells recognize virally infected cells and tumors. NK cell function depends on balanced signaling from activating receptors, recognizing…”
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SHP-1 expression and localization are associated with functional education of murine natural killer cells by Luu, T, Schmied, L, Sondergaard, JN, Saeed, MB, Meinke, S, Mohammad, D, Casoni, GP, Schlums, H, Truong, HM, Westerberg, L, Bryceson, Y, Alici, E, Wagner, AK, Kadri, N, Hoglund, P

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