Search Results - "Caskey, Robert C."

An extra-uterine system to physiologically support the extreme premature lamb by Partridge, Emily A., Davey, Marcus G., Hornick, Matthew A., McGovern, Patrick E., Mejaddam, Ali Y., Vrecenak, Jesse D., Mesas-Burgos, Carmen, Olive, Aliza, Caskey, Robert C., Weiland, Theodore R., Han, Jiancheng, Schupper, Alexander J., Connelly, James T., Dysart, Kevin C., Rychik, Jack, Hedrick, Holly L., Peranteau, William H., Flake, Alan W.

“…In the developed world, extreme prematurity is the leading cause of neonatal mortality and morbidity due to a combination of organ immaturity and iatrogenic…”
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Modulation of the inflammatory response by increasing fetal wound size or interleukin-10 overexpression determines wound phenotype and scar formation by Morris Jr, Michael W., Allukian III, Myron, Herdrich, Benjamin J., Caskey, Robert C., Zgheib, Carlos, Xu, Junwang, Dorsett-Martin, Wanda, Mitchell, Marc E., Liechty, Kenneth W.

“…Wound size impacts the threshold between scarless regeneration and reparative healing in the fetus with increased inflammation showed in fetal scar formation…”
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Mammalian Fetal Cardiac Regeneration After Myocardial Infarction Is Associated With Differential Gene Expression Compared With the Adult by Zgheib, Carlos, PhD, Allukian, Myron W., MD, Xu, Junwang, PhD, Morris, Michael W., MD, Caskey, Robert C., MD, Herdrich, Benjamin J., MD, Hu, Junyi, MD, Gorman, Joseph H., MD, Gorman, Robert C., MD, Liechty, Kenneth W., MD

“…Background In adults, myocardial infarction (MI) results in a brisk inflammatory response, myocardium loss, and scar formation. We have recently reported the…”
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Integration of Hands-On Team Training into Existing Curriculum Improves Both Technical and Nontechnical Skills in Laparoscopic Cholecystectomy by Caskey, Robert C., MD, MSc, Owei, Lily, BA, Rao, Raghavendra, MD, Riddle, Elijah W., MD, Brooks, Ari D., MD, FACS, Dempsey, Daniel T., MD, FACS, Morris, Jon B., MD, FACS, Neylan, Christopher J., BA, Williams, Noel N., MD, FRCSI, Dumon, Kristoffel R., MD, FACS

“…Objective Nontechnical skills are an essential component of surgical education and a major competency assessed by the ACGME milestones project. However, the…”
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Lentiviral-mediated over-expression of hyaluronan synthase-1 (HAS-1) decreases the cellular inflammatory response and results in regenerative wound repair by Caskey, Robert C, Allukian, Myron, Lind, Robert C, Herdrich, Benjamin J, Xu, Junwang, Radu, Antoneta, Mitchell, Marc E, Liechty, Kenneth W

“…Fetal wounds have been found to have increased levels of high-molecular-weight hyaluronan (HMW-HA) compared with those of adults. The primary enzyme…”
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Management of Pediatric Mild Traumatic Brain Injury by Caskey, Robert C., MD, MSc, Nance, Michael L., MD

“…mTBI is a very common and underdiagnosed problem in the pediatric population. While most children who receive appropriate management recover uneventfully…”
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In Situ Operating Room–Based Simulation: A Review by Owei, Lily, BA, Neylan, Christopher J., BA, Rao, Raghavendra, MD, Caskey, Robert C., MD, Morris, Jon B., MD, Sensenig, Richard, MS, MSEE, Brooks, Ari D., MD, Dempsey, Daniel T., MD, Williams, Noel N., MD, Atkins, Joshua H., MD, PhD, Baranov, Dimitry Y., MD, Dumon, Kristoffel R., MD

“…Objective To systematically review the literature surrounding operating room–based in situ training in surgery. Methods A systematic review was conducted of…”
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High ratio plasma resuscitation does not improve survival in pediatric trauma patients by Cannon, Jeremy W, Johnson, Michael A, Caskey, Robert C, Borgman, Matthew A, Neff, Lucas P

“…Damage control resuscitation including balanced resuscitation with high ratios of plasma (PLAS) and platelets (PLT) to packed red blood cells (PRBC) improves…”
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Mesenchymal stem cells correct impaired diabetic wound healing by decreasing ECM proteolysis by Xu, Junwang, Zgheib, Carlos, Hodges, Maggie M, Caskey, Robert C, Hu, Junyi, Liechty, Kenneth W

“…Impaired diabetic wound healing is associated with a dermal extracellular matrix protein profile favoring proteolysis; within the healing diabetic wound, this…”
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Dysregulation of collagen production in diabetes following recurrent skin injury: Contribution to the development of a chronic wound by Caskey, Robert C., Zgheib, Carlos, Morris, Michael, Allukian, Myron, Dorsett-Martin, Wanda, Xu, Junwang, Wu, Wenjie, Liechty, Kenneth W.

“…Recurrent injury has been implicated in the development of chronic diabetic wounds. We have developed a chronic diabetic wound model based upon recurrent…”
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Corrigendum: An extra-uterine system to physiologically support the extreme premature lamb by Partridge, Emily A, Davey, Marcus G, Hornick, Matthew A, McGovern, Patrick E, Mejaddam, Ali Y, Vrecenak, Jesse D, Mesas-Burgos, Carmen, Olive, Aliza, Caskey, Robert C, Weiland, Theodore R, Han, Jiancheng, Schupper, Alexander J, Connelly, James T, Dysart, Kevin C, Rychik, Jack, Hedrick, Holly L, Peranteau, William H, Flake, Alan W

“…This corrects the article DOI: 10.1038/ncomms15112…”
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SCF increases in utero-labeled stem cells migration and improves wound healing by Zgheib, Carlos, Xu, Junwang, Mallette, Andrew C., Caskey, Robert C., Zhang, Liping, Hu, Junyi, Liechty, Kenneth W.

“…ABSTRACT Diabetic skin wounds lack the ability to heal properly and constitute a major and significant complication of diabetes. Nontraumatic lower extremity…”
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Interprofessional Simulations to Inform Perioperative Facility Planning and Design by Torres-Landa, Samuel, Neylan, Christopher, Quinlan, Kristin, Klock, Christopher, Jefferson, Christi, Williams, Noel N., Caskey, Robert C., Greulich, Stephen, Kolb, Gretchen, Morgan, Cynthia, Mahoney, Kevin, Dumon, Kristoffel R.

“…The purpose of this study is to report our experience with interprofessional simulations, executed in a mock-up of a proposed perioperative space, that were…”
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Curriculum Using the In-Situ Operating Room Setting by Rao, Raghavendra, Caskey, Robert C., Owei, Lily, O’Connor, Kathleen, Riddle, Elijah, Dempsey, Daniel T., Atkins, Joshua, Baranov, Dimitry, Motuk, Gregory, Brooks, Ari D., Williams, Noel, Morris, Jon, Dumon, Kristoffel

“…The American College of Surgeons/Association of Program Directors in Surgery is a comprehensive, simulation-based curriculum for General Surgery residents…”
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“How To” Videos Improve Residents Performance of Essential Perioperative Electronic Medical Records and Clinical Tasks by Zoghbi, Veronica, Caskey, Robert C., Dumon, Kristoffel R., Soegaard Ballester, Jacqueline M., Brooks, Ari D., Morris, Jon B., Dempsey, Daniel T.

“…The ability to use electronic medical records (EMR) is an essential skill for surgical residents. However, frustration and anxiety surrounding EMR tasks may…”
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Correction: Corrigendum: An extra-uterine system to physiologically support the extreme premature lamb by Partridge, Emily A., Davey, Marcus G., Hornick, Matthew A., McGovern, Patrick E., Mejaddam, Ali Y., Vrecenak, Jesse D., Mesas-Burgos, Carmen, Olive, Aliza, Caskey, Robert C., Weiland, Theodore R., Han, Jiancheng, Schupper, Alexander J., Connelly, James T., Dysart, Kevin C., Rychik, Jack, Hedrick, Holly L., Peranteau, William H., Flake, Alan W.

“…Nature Communications 8: Article number: 15112 (2017); Published 25 April 2017; Updated 23 May 2017 A patent based on the work reported in this Article was…”
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Increased fetal wound size results in increased oxidative stress and promotes scar formation in fetal wounds by Zgheib, Carlos, PhD, Xu, Junwang, PhD, Caskey, Robert C., MD, Morris, Michael W., MD, Allukian, Myron W., MD, Hu, Junyi, MD, Liechty, Kenneth W., MD, FACS

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Multiple strategies must be pursued in the development of cellular therapies by Caskey, Robert C, Liechty, Kenneth W

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Recurrent injury of diabetic mice significantly delays wound closure and recapitulates the dysregulated inflammatory state seen in chronic diabetic wounds by Caskey, Robert C., MD, MS, Dorsett-Martin, Wanda A., DVM, Xu, Junwang, PhD, Zhang, Liping, MS, Wu, Wenjie, BA, Morris, Michael W., MD, Allukian, Myron, MD, Mitchell, Marc E., MD, FACS, Liechty, Kenneth W., MD, FACS

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Collagen production is dysregulated at both the transcriptional and post-transcriptional level in the progression from acute to chronic diabetic wound by Caskey, Robert C., MD, MS, Xu, Junwang, PhD, Allukian, Myron, MD, Morris, Michael W., MD, Dorsett-Martin, Wanda A., DVM, Wu, Wenjie, BA, Mitchell, Marc E., MD, FACS, Liechty, Kenneth W., MD, FACS

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