Myofunctional therapy for OSA: a meta-analysis

Myofunctional therapy (MT) improves obstructive sleep apnea (OSA) in patients. We systematically reviewed publications to evaluate MT as a treatment for OSA. We identified relevant articles and performed a meta-analysis on apnea-hypopnea index (AHI) scores, lowest oxygen saturation (LSAT), and Epwor...

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Bibliographic Details
Published in:	Expert review of respiratory medicine Vol. 16; no. 3; p. 285
Main Authors:	Meghpara, Sanket, Chohan, Moeed, Bandyopadhyay, Anuja, Kozlowski, Conrad, Casinas, Jameson, Kushida, Clete, Camacho, Macario
Format:	Journal Article
Language:	English
Published:	England 04-03-2022
Subjects:	Humans Myofunctional Therapy Sleep Apnea, Obstructive - diagnosis Sleep Apnea, Obstructive - therapy obstructive sleep apnea Myofunctional therapy upper airway exercises
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Summary:	Myofunctional therapy (MT) improves obstructive sleep apnea (OSA) in patients. We systematically reviewed publications to evaluate MT as a treatment for OSA. We identified relevant articles and performed a meta-analysis on apnea-hypopnea index (AHI) scores, lowest oxygen saturation (LSAT), and Epworth Sleepiness Scale (ESS). Search databases were retained as primary data sources with the search performed through 18 June 2021. Fifteen studies with 237 patients provided OSA outcomes before and after MT, which were analyzed for this meta-analysis. The mean AHI scores decreased from 28.0 ± 16.2/h to 18.6 ± 13.1/h. The AHI standard mean difference (SMD) is -1.34 (large effect) [95% CI -0.84, -1.85], (P < 0.00001). LSAT (197 patients) improved from 83.18 ± 6.10% to 85.13 ± 7.01%. The LSAT SMD is 0.44 [95% CI 0.75, 0.12], (P < 0.007). Sleepiness measured via ESS (156 patients) demonstrated a decrease from 12.71 ± 5.73 to 8.78 ± 5.80. The ESS SMD is -1.0 [95% CI -0.50, -1.50], (P < 0.0001).
ISSN:	1747-6356
DOI:	10.1080/17476348.2021.2001332