Search Results - "Casillas, Dionne"
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Chimeric Antigen by the Fusion of SARS-CoV-2 Receptor Binding Domain with the Extracellular Domain of Human CD154: A Promising Improved Vaccine Candidate
Published in Vaccines (Basel) (03-06-2022)“…COVID-19 is a respiratory viral disease caused by a new coronavirus called SARS-CoV-2. This disease has spread rapidly worldwide with a high rate of morbidity…”
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Identification of Vimentin as a Potential Therapeutic Target against HIV Infection
Published in Viruses (15-06-2016)“…A combination of antiviral drugs known as antiretroviral therapy (ART) has shown effectiveness against the human immunodeficiency virus (HIV). ART has markedly…”
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Stability in human serum and plasma of the HIV peptide drug candidate CIGB-210 and improved variants
Published in Biotechnology and applied biochemistry (01-09-2024)“…The peptide CIGB-210 inhibits HIV replication, inducing a rearrangement of vimentin intermediate filaments. The assessment of the in vitro serum and plasma…”
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A competitive ELISA for the quantitative determination of the novel anti-HIV drug candidate CIGB-210 in biological fluids
Published in Journal of immunoassay & immunochemistry (04-03-2019)“…The synthetic peptide CIGB-210 is a promising anti-HIV drug candidate shown to inhibit HIV replication in MT4 cells at the nanomolar range by triggering the…”
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Cell Penetration and Secondary Structure of a Synthetic Peptide with Anti-HIV Activity
Published in International journal of peptide research and therapeutics (01-12-2017)“…Peptidic drugs have many advantages as compared to small chemical molecules; however, they also possess some limitations as their poor membrane transducing…”
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Evidence of SARS-CoV-2 infection in postmortem lung, kidney, and liver samples, revealing cellular targets involved in COVID-19 pathogenesis
Published in Archives of virology (01-03-2023)“…There is an urgent need to understand severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-host interactions involved in virus spread and pathogenesis,…”
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Non-induced leukocyte extract reduces HIV replication and TNF secretion
Published in Biochemical and biophysical research communications (17-12-2004)“…According to UNAIDS, the global HIV/AIDS epidemic increased to 40 million the number of people living with the virus around the world. Dialyzable leukocyte…”
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Preliminary safety assessment of CIGB-210, an investigational peptide for HIV infection
Published in Human & experimental toxicology (01-01-2022)“…Current human immunodeficiency virus treatments need to be periodically administered lifelong. In this study we assess the effect of repeated doses of an…”
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Identification of a new therapeutic target and a potential therapeutic candidate for the treatment of HIV infection
Published in Biotecnología Aplicada (01-03-2017)Get full text
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Retroviral integration: A critical step in viral life cycle suitable for drug intervention
Published in Biotecnología Aplicada (01-12-2011)“…Retroviral integration is an essential stage in the life cycle of retroviruses. Viruses need to insert their DNA into the chromosomal DNA of the host cells…”
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Notes on HIV pathogenesis, therapy and eradication
Published in Biotecnología Aplicada“…This report summarizes the main topics delivered as lectures at the meeting Frontiers in HIV pathogenesis, Therapy and Eradication, held at the Whistler…”
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From AZT to treatment as prevention. The evolution of antiretroviral therapy for HIV/AIDS
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Remarks on the Conference HIV pathogenesis, virus versus host, Alberta, Canada, March 9-14, 2014
Published in Biotecnología Aplicada“…Combined anti-retroviral therapy has been really efficient in suppressing HIV replication, but it does not cure the infection. This is due to the permanency of…”
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