Search Results - "Casiano, Carlos A"

Alpha-Enolase: Emerging Tumor-Associated Antigen, Cancer Biomarker, and Oncotherapeutic Target by Almaguel, Frankis A, Sanchez, Tino W, Ortiz-Hernandez, Greisha L, Casiano, Carlos A

“…Alpha-enolase, also known as enolase-1 (ENO1), is a glycolytic enzyme that "moonlights" as a plasminogen receptor in the cell surface, particularly in tumors,…”
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Docosahexaenoic acid protection against palmitic acid‐induced lipotoxicity in NGF‐differentiated PC12 cells involves enhancement of autophagy and inhibition of apoptosis and necroptosis by Montero, Manuel L., Liu, Jo‐Wen, Orozco, José, Casiano, Carlos A., De Leon, Marino

“…Lipotoxicity (LTx) leads to cellular dysfunction and cell death and has been proposed to be an underlying process during traumatic and hypoxic injuries and…”
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Plasma metabolomics profiles in Black and White participants of the Adventist Health Study-2 cohort by Butler, Fayth M, Utt, Jason, Mathew, Roy O, Casiano, Carlos A, Montgomery, Suzanne, Wiafe, Seth A, Lampe, Johanna W, Fraser, Gary E

“…Black Americans suffer disparities in risk for cardiometabolic and other chronic diseases. Findings from the Adventist Health Study-2 (AHS-2) cohort have shown…”
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Underrepresented minority high school and college students report STEM-pipeline sustaining gains after participating in the Loma Linda University Summer Health Disparities Research Program by Salto, Lorena M, Riggs, Matt L, Delgado De Leon, Daisy, Casiano, Carlos A, De Leon, Marino

“…An urgent need exists for graduate and professional schools to establish evidence-based STEM (science, technology, engineering, and math) pipeline programs to…”
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Glucocorticoid Receptor and β-Catenin Interact in Prostate Cancer Cells and Their Co-Inhibition Attenuates Tumorsphere Formation, Stemness, and Docetaxel Resistance by Martinez, Shannalee R, Elix, Catherine C, Ochoa, Pedro T, Sanchez-Hernandez, Evelyn S, Alkashgari, Hossam R, Ortiz-Hernandez, Greisha L, Zhang, Lubo, Casiano, Carlos A

“…Therapy resistance hinders the efficacy of anti-androgen therapies and taxane-based chemotherapy for advanced prostate cancer (PCa). Glucocorticoid receptor…”
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TSLP as a Potential Therapy in the Treatment of CRLF2 B Cell Acute Lymphoblastic Leukemia by Alkashgari, Hossam R, Ruiz-Jimenez, Caleb, Stoian, Cornelia, Coats, Jacqueline S, Baez, Ineavely, Chirshev, Evgeny, Martinez, Shannalee R, Dovat, Sinisa, Francis-Boyle, Olivia L, Casiano, Carlos A, Payne, Kimberly J

“…Cytokine receptor-like factor 2 B-cell acute lymphoblastic leukemia (CRLF2 B-ALL) is a high-risk subtype characterized by CRLF2 overexpression with poor…”
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Duocarmycin SA Reduces Proliferation and Increases Apoptosis in Acute Myeloid Leukemia Cells In Vitro by Chen, William A, Williams, Terry G, So, Leena, Drew, Natalie, Fang, Jie, Ochoa, Pedro, Nguyen, Nhi, Jawhar, Yasmeen, Otiji, Jide, Duerksen-Hughes, Penelope J, Reeves, Mark E, Casiano, Carlos A, Jin, Hongjian, Dovat, Sinisa, Yang, Jun, Boyle, Kristopher E, Francis-Boyle, Olivia L

“…Acute myeloid leukemia (AML) is a hematological malignancy that is characterized by an expansion of immature myeloid precursors. Despite therapeutic advances,…”
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Racial differences in the expression of inhibitors of apoptosis (IAP) proteins in extracellular vesicles (EV) from prostate cancer patients by Khan, Salma, Simpson, Jennifer, Lynch, James C, Turay, David, Mirshahidi, Saied, Gonda, Amber, Sanchez, Tino W, Casiano, Carlos A, Wall, Nathan R

“…African-American men with prostate cancer typically develop more aggressive tumors than men from other racial/ethnic groups, resulting in a disproportionately…”
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Tumor-associated Antigen Arrays for the Serological Diagnosis of Cancer by Casiano, Carlos A., Mediavilla-Varela, Melanie, Tan, Eng M.

“…The recognition that human tumors stimulate the production of autoantibodies against autologous cellular proteins called tumor-associated antigens (TAAs) has…”
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A Health Profile of African Immigrant Men in the United States by Malika, Nipher, Roberts, Lisa R., Casiano, Carlos A., Montgomery, Susanne

“…African immigrants (AI) are the fastest growing group of immigrants to the U.S. however, their health and health practices remains poorly characterized. Thus,…”
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The 22Rv1 prostate cancer cell line carries mixed genetic ancestry: Implications for prostate cancer health disparities research using pre‐clinical models by Woods‐Burnham, Leanne, Basu, Anamika, Cajigas‐Du Ross, Christina K., Love, Arthur, Yates, Clayton, De Leon, Marino, Roy, Sourav, Casiano, Carlos A.

“…Background Understanding how biological factors contribute to prostate cancer (PCa) health disparities requires mechanistic functional analysis of specific…”
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LEDGF/p75 Overexpression Attenuates Oxidative Stress-Induced Necrosis and Upregulates the Oxidoreductase ERP57/PDIA3/GRP58 in Prostate Cancer by Basu, Anamika, Cajigas-Du Ross, Christina K, Rios-Colon, Leslimar, Mediavilla-Varela, Melanie, Daniels-Wells, Tracy R, Leoh, Lai Sum, Rojas, Heather, Banerjee, Hiya, Martinez, Shannalee R, Acevedo-Martinez, Stephanny, Casiano, Carlos A

“…Prostate cancer (PCa) mortality is driven by highly aggressive tumors characterized by metastasis and resistance to therapy, and this aggressiveness is…”
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Differential expression of peroxiredoxins in prostate cancer: Consistent upregulation of PRDX3 and PRDX4 by Basu, Anamika, Banerjee, Hiya, Rojas, Heather, Martinez, Shannalee R., Roy, Sourav, Jia, Zhenyu, Lilly, Michael B., De León, Marino, Casiano, Carlos A.

“…BACKGROUND The peroxiredoxins (PRDXs) are emerging as regulators of antioxidant defense, apoptosis, and therapy resistance in cancer. Because their…”
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Expression of the stress response oncoprotein LEDGF/p75 in human cancer: a study of 21 tumor types by Basu, Anamika, Rojas, Heather, Banerjee, Hiya, Cabrera, Irena B, Perez, Kayla Y, De León, Marino, Casiano, Carlos A

“…Oxidative stress-modulated signaling pathways have been implicated in carcinogenesis and therapy resistance. The lens epithelium derived growth factor p75…”
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Docetaxel-induced prostate cancer cell death involves concomitant activation of caspase and lysosomal pathways and is attenuated by LEDGF/p75 by Mediavilla-Varela, Melanie, Pacheco, Fabio J, Almaguel, Frankis, Perez, Jossymar, Sahakian, Eva, Daniels, Tracy R, Leoh, Lai Sum, Padilla, Amelia, Wall, Nathan R, Lilly, Michael B, De Leon, Marino, Casiano, Carlos A

“…Hormone-refractory prostate cancer (HRPC) is characterized by poor response to chemotherapy and high mortality, particularly among African American men when…”
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The Nuclear Dense Fine Speckled (DFS) Immunofluorescence Pattern: Not All Roads Lead to DFS70/LEDGFp75 by Sanchez-Hernandez, Evelyn S, Ortiz-Hernandez, Greisha L, Ochoa, Pedro T, Reeves, Michael, Bizzaro, Nicola, Andrade, Luis E C, Mahler, Michael, Casiano, Carlos A

“…The monospecific dense fine speckled (DFS) immunofluorescence assay (IFA) pattern is considered a potential marker to aid in exclusion of antinuclear antibody…”
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Physician Consultations, Prostate Cancer Knowledge, and PSA Screening of African American Men in the Era of Shared Decision-Making by Woods-Burnham, Leanne, Stiel, Laura, Wilson, Colwick, Montgomery, Susanne, Durán, Alfonso M., Ruckle, Herbert R., Thompson, Rupert A., De León, Marino, Casiano, Carlos A.

“…African American (AA)/Black men are more likely to develop aggressive prostate cancer (PCa), yet less likely to be screened despite guidelines espousing shared…”
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Preferential Autoimmune Response in Prostate Cancer to Cyclin B1 in a Panel of Tumor-Associated Antigens by Casiano, Carlos A., Qian, Wei, Ortega, Rosalia, Li, Jitian, Dai, Liping, Zhang, Jian-Ying

“…Previous studies have demonstrated that sera from patients with prostate cancer (PCa) contain autoantibodies that react with tumor-associated antigens (TAAs)…”
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Glucocorticoid Receptor Regulates and Interacts with LEDGF/p75 to Promote Docetaxel Resistance in Prostate Cancer Cells by Sanchez-Hernandez, Evelyn S, Ochoa, Pedro T, Suzuki, Tise, Ortiz-Hernandez, Greisha L, Unternaehrer, Juli J, Alkashgari, Hossam R, Diaz Osterman, Carlos J, Martinez, Shannalee R, Chen, Zhong, Kremsky, Isaac, Wang, Charles, Casiano, Carlos A

“…Patients with advanced prostate cancer (PCa) invariably develop resistance to anti-androgen therapy and taxane-based chemotherapy. Glucocorticoid receptor (GR)…”
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Enhancement of Antibody Detection in Cancer Using Panel of Recombinant Tumor-associated Antigens by ZHANG, Jian-Ying, CASIANO, Carlos A, PENG, Xuan-Xian, KOZIOL, James A, CHAN, Edward K. L, TAN, Eng M

“…Cancer sera contain antibodies which react with a unique group of autologous cellular antigens called tumor-associated antigens (TAAs). This study determines…”
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