Search Results - "Cashman, N."

Respiratory and haemodynamic effects of acute postoperative pain management: evidence from published data by Cashman, J.N., Dolin, S.J.

“…This study examines the evidence from published data concerning the adverse respiratory and haemodynamic effects of three analgesic techniques after major…”
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Tolerability of acute postoperative pain management: nausea, vomiting, sedation, pruritis, and urinary retention. Evidence from published data by Dolin, S.J., Cashman, J.N.

“…This review examines the evidence from published data concerning the tolerability (indicated by the incidence of nausea, vomiting, sedation, pruritis, and…”
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Effectiveness of acute postoperative pain management: I. Evidence from published data by Dolin, S.J., Cashman, J.N., Bland, J.M.

“…This review examines the evidence from published data concerning the incidence of moderate-severe and of severe pain after major surgery, with three analgesic…”
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The mechanisms of action of NSAIDs in analgesia by CASHMAN, J. N

“…Traditionally, the analgesic action of nonsteroidal anti-inflammatory drugs (NSAIDs) has been explained on the basis of their inhibition of the enzymes that…”
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Iatrogenic Creutzfeldt-Jakob disease at the millennium by BROWN, P, PREECE, M, D'AIGNAUX, J. H, CERVENAKOVA, L, FRADKIN, J, SCHONBERGER, L. B, COLLINS, S. J, BRANDEL, J.-P, SATO, T, MCSHANE, L, ZERR, I, FLETCHER, A, WILL, R. G, POCCHIARI, M, CASHMAN, N. R

“…The causes and geographic distribution of 267 cases of iatrogenic Creutzfeldt-Jakob disease (CJD) are here updated at the millennium. Small numbers of…”
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Cerebral degeneration predicts survival in amyotrophic lateral sclerosis by Kalra, S, Vitale, A, Cashman, N R, Genge, A, Arnold, D L

“…Objective: To determine the relationship of cerebral degeneration with survival in amyotrophic lateral sclerosis (ALS). Methods: Patients with probable or…”
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GERSTMANN-STRÄUSSLER-SCHEINKER DISEASE DUE TO A NOVEL PRION PROTEIN GENE MUTATION by HINNELL, C, COULTHART, M. B, FURTADO, S, JANSEN, G. H, CASHMAN, N. R, LAUZON, J, CLARK, A, COSTELLO, F, WHITE, C, MIDHA, R, WIEBE, S

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Chronic Exposure to Dietary Sterol Glucosides is Neurotoxic to Motor Neurons and Induces an ALS–PDC Phenotype by Tabata, R. C., Wilson, J. M. B., Ly, P., Zwiegers, P., Kwok, D., Van Kampen, J. M., Cashman, N., Shaw, C. A.

“…Epidemiological studies of the Guamanian variants of amyotrophic lateral sclerosis (ALS) and parkinsonism, amyotrophic lateral sclerosis–parkinsonism dementia…”
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Accessibility of a critical prion protein region involved in strain recognition and its implications for the early detection of prions by Yuan, J, Dong, Z, Guo, J.-P, McGeehan, J, Xiao, X, Wang, J, Cali, I, McGeer, P. L, Cashman, N. R, Bessen, R, Surewicz, W. K, Kneale, G, Petersen, R. B, Gambetti, P, Zou, W. Q

“…Human prion diseases are characterized by the accumulation in the brain of proteinase K (PK)-resistant prion protein designated PrP27 - 30 detectable by the…”
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Monomeric Cu,Zn-superoxide Dismutase Is a Common Misfolding Intermediate in the Oxidation Models of Sporadic and Familial Amyotrophic Lateral Sclerosis[boxs] by Rakhit, Rishi, Crow, John P., Lepock, James R., Kondejewski, Leslie H., Cashman, Neil R., Chakrabartty, Avijit

“…Proteinacious intracellular aggregates in motor neurons are a key feature of both sporadic and familial amyotrophic lateral sclerosis (ALS). These inclusion…”
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Kennedy's disease : Caspase cleavage of the androgen receptor is a crucial event in cytotoxicity by ELLERBY, L. M, HACKAM, A. S, HAYDEN, M. R, BREDESEN, D. E, PROPP, S. S, ELLERBY, H. M, RABIZADEH, S, CASHMAN, N. R, TRIFIRO, M. A, PINSKY, L, WELLINGTON, C. L, SALVESEN, G. S

“…X-linked spinal and bulbar muscular atrophy (SBMA), Kennedy's disease, is a degenerative disease of the motor neurons that is associated with an increase in…”
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Prion protein expression in human leukocyte differentiation by DODELET, V. C, CASHMAN, N. R

“…The cellular isoform of the prion protein (PrPC) is a small glycoprotein attached to the outer leaflet of the plasma membrane by a glycosylphosphatidylinositol…”
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Propagated protein misfolding: New opportunities for therapeutics, new public health risk by Cashman, N R

“…There is now good consensus that propagated protein misfolding is the underlying mechanism for the infectious prion diseases (Creutzfeldt-Jakob disease in…”
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Recovery of N-acetylaspartate in corticomotor neurons of patients with ALS after riluzole therapy by Kalra, Sanjay, Cashman, Neil R, Genge, Angela, Arnold, Douglas L

“…RILUZOLE, a glutamate antagonist, has been shown to be efficacious in the treatment of patients with amyotrophic lateral sclerosis (ALS), allowing prolonged…”
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Temporal lobe epilepsy caused by domoic acid intoxication: evidence for glutamate receptor-mediated excitotoxicity in humans by Cendes, F, Andermann, F, Carpenter, S, Zatorre, R J, Cashman, N R

“…We describe the development of temporal lobe epilepsy in an 84-year-old man who had suffered domoic acid intoxication. Following intoxication he had nausea,…”
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Monitoring signals for vaccine safety: the assessment of individual adverse event reports by an expert advisory committee by Collet, J.-P, MacDonald, N, Cashman, N, Pless, R

“…Monitoring vaccine safety is a complex and shared responsibility. It can be carried out in many ways, one of which is the reporting of individual cases of…”
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Nearly ubiquitous tissue distribution of the scrapie agent precursor protein by BENDHEIM, P. E, BROWN, H. R, RUDELLI, R. D, SCALA, L. J, GOLLER, N. L, WEN, G. Y, KASCSAK, R. J, CASHMAN, N. R, BOLTON, D. C

“…The "modified host protein" model of scrapie proposes that the transmissible agent is composed of the degradation-resistant protein, Sp33-37, and that clinical…”
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A multicenter, randomized, double-blinded trial of pyridostigmine in postpolio syndrome by TROJAN, D. A, COLLET, J.-P, ROBINSON, A, FINCH, L, DUCRUET, T, CASHMAN, N. R, SHAPIRO, S, JUBELT, B, MILLER, R. G, AGRE, J. C, MUNSAT, T. L, HOLLANDER, D, TANDAN, R, GRANGER, C

“…Postpoliomyelitis syndrome (PPS) is likely due to degeneration and dysfunction of terminal axons of enlarged postpolio motor units. Age-related decline in…”
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The Lipid Peroxidation Product 4-Hydroxynonenal Impairs Glutamate and Glucose Transport and Choline Acetyltransferase Activity in NSC-19 Motor Neuron Cells by Pedersen, Ward A., Cashman, Neil R., Mattson, Mark P.

“…Both oxidative stress and excitotoxicity are implicated in the pathogenesis of a number of neurodegenerative disorders, such as amyotrophic lateral sclerosis…”
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The management of peri- and postprocedural pain in interventional radiology: a narrative review by Cashman, Jeremy N, Ng, Lenny

“…Interventional radiology encompasses a wide range of procedures and the degree of associated pain depends predominantly on the procedure being undertaken…”
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