Search Results - "Cash, Sydney S."
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1
Epilepsy as a Disorder of Cortical Network Organization
Published in The Neuroscientist (Baltimore, Md.) (01-08-2012)“…The brain is naturally considered as a network of interacting elements which, when functioning properly, produces an enormous range of dynamic, adaptable…”
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2
The generation and propagation of the human alpha rhythm
Published in Proceedings of the National Academy of Sciences - PNAS (19-11-2019)“…The alpha rhythm is the longest-studied brain oscillation and has been theorized to play a key role in cognition. Still, its physiology is poorly understood…”
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3
The Emergence of Single Neurons in Clinical Neurology
Published in Neuron (Cambridge, Mass.) (08-04-2015)“…Single neuron actions and interactions are the sine qua non of brain function, and nearly all diseases and injuries of the CNS trace their clinical sequelae to…”
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4
Neurophysiological dynamics of phrase-structure building during sentence processing
Published in Proceedings of the National Academy of Sciences - PNAS (02-05-2017)“…Although sentences unfold sequentially, one word at a time, most linguistic theories propose that their underlying syntactic structure involves a tree of…”
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5
Enhanced Dendritic Compartmentalization in Human Cortical Neurons
Published in Cell (18-10-2018)“…The biophysical features of neurons shape information processing in the brain. Cortical neurons are larger in humans than in other species, but it is unclear…”
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Dynamic Balance of Excitation and Inhibition in Human and Monkey Neocortex
Published in Scientific reports (16-03-2016)“…Balance of excitation and inhibition is a fundamental feature of in vivo network activity and is important for its computations. However, its presence in the…”
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7
Association of epileptiform abnormalities and seizures in Alzheimer disease
Published in Neurology (20-10-2020)“…OBJECTIVETo examine the relationship between scalp EEG biomarkers of hyperexcitability in Alzheimer disease (AD) and to determine how these electric biomarkers…”
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Development of Expert-Level Automated Detection of Epileptiform Discharges During Electroencephalogram Interpretation
Published in JAMA neurology (01-01-2020)“…Interictal epileptiform discharges (IEDs) in electroencephalograms (EEGs) are a biomarker of epilepsy, seizure risk, and clinical decline. However, there is a…”
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9
Streamlined, Inexpensive 3D Printing of the Brain and Skull
Published in PloS one (21-08-2015)“…Neuroimaging technologies such as Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) collect three-dimensional data (3D) that is typically viewed on…”
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10
Sequential Processing of Lexical, Grammatical, and Phonological Information Within Broca's Area
Published in Science (American Association for the Advancement of Science) (16-10-2009)“…Words, grammar, and phonology are linguistically distinct, yet their neural substrates are difficult to distinguish in macroscopic brain regions. We…”
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11
Rotating waves during human sleep spindles organize global patterns of activity that repeat precisely through the night
Published in eLife (15-11-2016)“…During sleep, the thalamus generates a characteristic pattern of transient, 11-15 Hz sleep spindle oscillations, which synchronize the cortex through…”
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Travelling spindles create necessary conditions for spike-timing-dependent plasticity in humans
Published in Nature communications (15-02-2021)“…Sleep spindles facilitate memory consolidation in the cortex during mammalian non-rapid eye movement sleep. In rodents, phase-locked firing during spindles may…”
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13
Rapid fragmentation of neuronal networks at the onset of propofol-induced unconsciousness
Published in Proceedings of the National Academy of Sciences - PNAS (04-12-2012)“…The neurophysiological mechanisms by which anesthetic drugs cause loss of consciousness are poorly understood. Anesthetic actions at the molecular, cellular,…”
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14
Detection of mesial temporal lobe epileptiform discharges on intracranial electrodes using deep learning
Published in Clinical neurophysiology (01-01-2020)“…•We developed a deep learning algorithm to detect mesial temporal lobe epileptiform discharges on intracranial EEG.•Convolutional neural networks with simple…”
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15
Continuous electroencephalography predicts delayed cerebral ischemia after subarachnoid hemorrhage: A prospective study of diagnostic accuracy
Published in Annals of neurology (01-05-2018)“…Objective Delayed cerebral ischemia (DCI) is a common, disabling complication of subarachnoid hemorrhage (SAH). Preventing DCI is a key focus of neurocritical…”
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16
Widespread ripples synchronize human cortical activity during sleep, waking, and memory recall
Published in Proceedings of the National Academy of Sciences - PNAS (12-07-2022)“…Declarative memory encoding, consolidation, and retrieval require the integration of elements encoded in widespread cortical locations. The mechanism whereby…”
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17
Quantifying seizure termination patterns reveals limited pathways to seizure end
Published in Neurobiology of disease (01-04-2022)“…Despite their possible importance in the design of novel neuromodulatory approaches and in understanding status epilepticus, the dynamics and mechanisms of…”
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Local and distant responses to single pulse electrical stimulation reflect different forms of connectivity
Published in NeuroImage (Orlando, Fla.) (15-08-2021)“…Measuring connectivity in the human brain involves innumerable approaches using both noninvasive (fMRI, EEG) and invasive (intracranial EEG or iEEG) recording…”
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Modular pipeline for reconstruction and localization of implanted intracranial ECoG and sEEG electrodes
Published in PloS one (07-07-2023)“…Implantation of electrodes in the brain has been used as a clinical tool for decades to stimulate and record brain activity. As this method increasingly…”
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Decoding word and category-specific spatiotemporal representations from MEG and EEG
Published in NeuroImage (Orlando, Fla.) (14-02-2011)“…The organization and localization of lexico-semantic information in the brain has been debated for many years. Specifically, lesion and imaging studies have…”
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