Search Results - "Cash, N"
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Parental rights or parental wrongs: Parents' metacognitive knowledge of the factors that influence their school choice decisions
Published in PloS one (18-04-2024)“…School choice initiatives-which empower parents to choose which schools their children attend-are built on the assumptions that parents know what features of a…”
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High-Throughput Cryo-EM Enabled by User-Free Preprocessing Routines
Published in Structure (London) (07-07-2020)“…Single-particle cryoelectron microscopy (cryo-EM) continues to grow into a mainstream structural biology technique. Recent developments in data collection…”
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3
Targeted Mutational Analysis of Cortisol-Producing Adenomas
Published in The journal of clinical endocrinology and metabolism (01-02-2022)“…Somatic gene mutations have been identified in only about half of cortisol-producing adenomas (CPAs). Affected genes include PRKACA, GNAS, PRKAR1A, and CTNNB1…”
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CRISPR/Cas9 knockout of USP18 enhances type I IFN responsiveness and restricts HIV‐1 infection in macrophages
Published in Journal of leukocyte biology (13-02-2018)“…The IFN‐stimulated gene ubiquitin‐specific proteinase 18 (USP18) encodes a protein that negatively regulates T1 IFN signaling via stearic inhibition of JAK1…”
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5
Murine Salivary Amylase Protects Against Streptococcus mutans -Induced Caries
Published in Frontiers in physiology (02-07-2021)“…Saliva protects dental surfaces against cavities (i. e., dental caries), a highly prevalent infectious disease frequently associated with acidogenic …”
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Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma
Published in PLoS biology (01-12-2020)“…When the J-domain of the heat shock protein DnaJB1 is fused to the catalytic (C) subunit of cAMP-dependent protein kinase (PKA), replacing exon 1, this fusion…”
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Emergence and Evolutionary Response of Vibrio cholerae to Novel Bacteriophage, Democratic Republic of the Congo
Published in Emerging infectious diseases (01-12-2022)“…Cholera causes substantial illness and death in Africa. We analyzed 24 toxigenic Vibrio cholerae O1 strains isolated in 2015–2017 from patients in the Great…”
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Ancestral Origin and Dissemination Dynamics of Reemerging Toxigenic Vibrio cholerae , Haiti
Published in Emerging infectious diseases (01-10-2023)“…The 2010 cholera epidemic in Haiti was thought to have ended in 2019, and the Prime Minister of Haiti declared the country cholera-free in February 2022. On…”
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A thermostable Cas12b from Brevibacillus leverages one-pot discrimination of SARS-CoV-2 variants of concern
Published in EBioMedicine (01-03-2022)“…Current SARS-CoV-2 detection platforms lack the ability to differentiate among variants of concern (VOCs) in an efficient manner. CRISPR/Cas (Clustered…”
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10
Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4
Published in eLife (31-07-2024)“…PIP 3 -dependent Rac exchanger 1 (P-Rex1) is abundantly expressed in neutrophils and plays central roles in chemotaxis and cancer metastasis by serving as a…”
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High-resolution cryo-EM using beam-image shift at 200 keV
Published in IUCrJ (01-11-2020)“…Recent advances in single-particle cryo-electron microscopy (cryo-EM) data collection utilize beam-image shift to improve throughput. Despite implementation on…”
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Establishment and characterization of a telomerase immortalized human gingival epithelial cell line
Published in Journal of periodontal research (01-12-2013)“…Background and Objective Gingival keratinocytes are used in model systems to investigate the interaction between periodontal bacteria and the epithelium in the…”
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Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3
Published in Structure (London) (03-05-2016)“…Phosphatidylinositol 3,4,5-trisphosphate (PIP3)-dependent Rac exchanger 1 (P-Rex1) is a Rho guanine nucleotide exchange factor synergistically activated by…”
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Comparison of SARS-CoV-2 Receptors Expression in Primary Endothelial Cells and Retinoic Acid-Differentiated Human Neuronal Cells
Published in Viruses (30-10-2021)“…SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) is primarily responsible for coronavirus disease (COVID-19) and it is characterized by respiratory…”
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A comparison of different chemical sanitizers for inactivating Escherichia coli O157:H7 and Listeria monocytogenes in solution and on apples, lettuce, strawberries, and cantaloupe
Published in Journal of food protection (01-04-2004)“…Ozone (3 ppm), chlorine dioxide (3 and 5 ppm), chlorinated trisodium phosphate (100- and 200-ppm chlorine), and peroxyacetic acid (80 ppm) were assessed for…”
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Molecular Basis of the Toxigenic Vibrio cholerae O1 Serotype Switch from Ogawa to Inaba in Haiti
Published in Microbiology spectrum (14-02-2023)“…Toxigenic Vibrio cholerae O1 serotype Ogawa was introduced involuntarily into Haiti in October 2010, and virtually all of the clinical strains isolated during…”
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Oxidative stress in acute pancreatitis: lost in translation?
Published in Free radical research (01-11-2013)“…Oxidative stress has been implicated in the pathogenesis of acute pancreatitis, a severe and debilitating inflammation of the pancreas that carries a…”
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Cryo-electron microscopy structure and analysis of the P-Rex1-Gβγ signaling scaffold
Published in Science advances (16-10-2019)“…PIP -dependent Rac exchanger 1 (P-Rex1) is activated downstream of G protein-coupled receptors to promote neutrophil migration and metastasis. The structure of…”
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Harmine enhances the activity of the HIV-1 latency-reversing agents ingenol A and SAHA
Published in Biology open (21-12-2020)“…Infection with human immunodeficiency virus 1 (HIV-1) remains incurable because long-lived, latently-infected cells persist during prolonged antiretroviral…”
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Postharvest Treatments for the Reduction of Mancozeb in Fresh Apples
Published in Journal of agricultural and food chemistry (01-06-2001)“…The objective of this study was to determine the effectiveness of chlorine, chlorine dioxide, ozone, and hydrogen peroxyacetic acid (HPA) treatments on the…”
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