Search Results - "Casey, Orla M."

Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors by Agarwal, Supreet, Hynes, Paul G., Tillman, Heather S., Lake, Ross, Abou-Kheir, Wassim G., Fang, Lei, Casey, Orla M., Ameri, Amir H., Martin, Philip L., Yin, Juan Juan, Iaquinta, Phillip J., Karthaus, Wouter R., Clevers, Hans C., Sawyers, Charles L., Kelly, Kathleen

“…Primary prostate cancer almost always has a luminal phenotype. However, little is known about the stem/progenitor properties of transformed cells within…”
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Prostate cancer-derived holoclones: a novel and effective model for evaluating cancer stemness by Flynn, Louise, Barr, Martin P., Baird, Anne-Marie, Smyth, Paul, Casey, Orla M., Blackshields, Gordon, Greene, John, Pennington, Stephen R., Hams, Emily, Fallon, Padraic G., O’Leary, John, Sheils, Orla, Finn, Stephen P.

“…Prostate cancer accounts for approximately 13.5% of all newly diagnosed male cancer cases. Significant clinical burdens remain in terms of ineffective…”
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TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation by Casey, Orla M, Fang, Lei, Hynes, Paul G, Abou-Kheir, Wassim G, Martin, Philip L, Tillman, Heather S, Petrovics, Gyorgy, Awwad, Hibah O, Ward, Yvona, Lake, Ross, Zhang, Luhua, Kelly, Kathleen

“…Genomic rearrangements commonly occur in many types of cancers and often initiate or alter the progression of disease. Here we describe an in vivo mouse model…”
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EGR1 regulates angiogenic and osteoclastogenic factors in prostate cancer and promotes metastasis by Li, Lechen, Ameri, Amir H., Wang, Simeng, Jansson, Keith H., Casey, Orla M., Yang, Qi, Beshiri, Michael L., Fang, Lei, Lake, Ross G., Agarwal, Supreet, Alilin, Aian N., Xu, Wanhai, Yin, JuanJuan, Kelly, Kathleen

“…Early growth response-1 ( EGR1 ) is a transcription factor correlated with prostate cancer (PC) progression in a variety of contexts. For example, EGR1 levels…”
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Loss of Androgen-Regulated MicroRNA 1 Activates SRC and Promotes Prostate Cancer Bone Metastasis by Liu, Yen-Nien, Yin, JuanJuan, Barrett, Ben, Sheppard-Tillman, Heather, Li, Dongmei, Casey, Orla M., Fang, Lei, Hynes, Paul G., Ameri, Amir H., Kelly, Kathleen

“…Bone metastasis is the hallmark of progressive and castration-resistant prostate cancers. MicroRNA 1 (miR-1) levels are decreased in clinical samples of…”
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Analysis of gene expression in non-regressed and regressed bovine corpus luteum tissue using a customized ovarian cDNA array by Casey, Orla M., Morris, Dermot G., Powell, Richard, Sreenan, Joseph M., Fitzpatrick, Richard

“…The lifespan of the bovine corpus luteum (CL) is an important factor in the control of normal ovarian cyclicity and the establishment and maintenance of…”
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Postmortem stability of RNA isolated from bovine reproductive tissues by Fitzpatrick, Richard, Casey, Orla M, Morris, Dermot, Smith, Terry, Powell, Richard, Sreenan, Joseph M

“…Molecular biology is being increasingly used to address the complex problem of bovine infertility. One common concern shared by many of these studies is the…”
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Analysis of gene expression in the bovine corpus luteum through generation and characterisation of 960 ESTs by Casey, Orla M., Fitzpatrick, Richard, McInerney, James O., Morris, Dermot G., Powell, Richard, Sreenan, Joseph M.

“…To gain new insights into gene identity and gene expression in the bovine corpus luteum (CL) a directionally cloned CL cDNA library was constructed, screened…”
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Abstract B28: TMPRSS2- driven ERG in primary prostate epithelium demonstrates castration-resistant expression and expands a unique population of progenitor cells by Casey, Orla M., Hynes, Paul G., Fang, Lei, Abou-Kheir, Wassim G., Martin, Philip L., Tillman, Heather S., Awwad, Hibah O., Zhang, Luhua, Kelly, Kathleen

“…It has become increasingly appreciated that recurrent genomic rearrangements contribute to the genesis of solid tumors. The genomic rearrangement of the Ets…”
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Abstract C58: The identification and characterization of prostate adenocarcinoma tumor-initiating cells by Hynes, Paul G., Abou-Kheir, Wassim G., Casey, Orla M., Fang, Lei, Liu, Yen-Nien, Sheppard-Tillman, Heather, Martin, Philip, Kelly, Kathleen

“…The phenotype of prostate adenocarcinoma tumor initiating cells, also called cancer stem cells, has not been determined for primary prostate tumors. Both…”
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Abstract 3240: A transgenic mouse model of a common genetic aberration in prostate cancer: Chromosomal rearrangement of TMPRSS2:ERG by Casey, Orla M., Awwad, Hibah, Zhang, Luhua, Fang, Lei, Hynes, Paul G., Abou-Kheir, Wassim G., Martin, Philip, Kelly, Kathleen

“…The most prevalent gene fusion identified in prostate cancer (PC) to date is the recurrent fusion of the 5’ region of Transmembrane Serine Protease 2 (TMPRSS2)…”
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Serum ionized calcium: evaluation of the Analyte +2 calcium analyser in a clinical chemistry laboratory by Freaney, R, Casey, O M, Quinn, T, Muldowney, F P

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