Search Results - "Casetti, Rita"
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Immunological signature in human cases of monkeypox infection in 2022 outbreak: an observational study
Published in The Lancet infectious diseases (01-03-2023)“…An unprecedented global monkeypox outbreak started in May, 2022. No data are yet available about the dynamics of the immune response against monkeypox virus…”
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Antioxidant and anti-inflammatory activities of extracts from Cassia alata, Eleusine indica, Eremomastax speciosa, Carica papaya and Polyscias fulva medicinal plants collected in Cameroon
Published in PloS one (04-08-2014)“…The vast majority of the population around the world has always used medicinal plants as first source of health care to fight infectious and non infectious…”
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Myocarditis-associated necrotizing coronary vasculitis: incidence, cause, and outcome
Published in European heart journal (21-04-2021)“…Necrotizing coronary vasculitis (NCV) is a rare entity usually associated to myocarditis which incidence, cause, and response to therapy is unreported. Among…”
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The unbalanced p53/SIRT1 axis may impact lymphocyte homeostasis in COVID-19 patients
Published in International journal of infectious diseases (01-04-2021)“…•Significant reduction of SIRT1 in COVID-19 patients may play a role in the maintenance of p53 in the active form.•Significant increase of p21 in COVID-19…”
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Myeloid-Derived Suppressor Cells in COVID-19: The Paradox of Good
Published in Frontiers in immunology (27-04-2022)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic. Viral…”
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Kinetics of the B- and T-Cell Immune Responses After 6 Months From SARS-CoV-2 mRNA Vaccination in Patients With Rheumatoid Arthritis
Published in Frontiers in immunology (28-02-2022)“…To assess the kinetics of the humoral and cell-mediated responses after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination in rheumatoid…”
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Myeloid-Derived Suppressor Cells Specifically Suppress IFN-γ Production and Antitumor Cytotoxic Activity of Vδ2 T Cells
Published in Frontiers in immunology (06-06-2018)“…γδ T cells represent less than 5% of circulating T cells; they exert a potent cytotoxic function against tumor or infected cells and secrete cytokines like…”
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A new procedure to analyze polymorphonuclear myeloid derived suppressor cells in cryopreserved samples cells by flow cytometry
Published in PloS one (30-08-2018)“…Myeloid derived suppressor cells (MDSC) is a heterogeneous subset of immature and mature cells of the myeloid lineage, undergoing expansion during pathologic…”
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In Acute Dengue Infection, High TIM-3 Expression May Contribute to the Impairment of IFNγ Production by Circulating Vδ2 T Cells
Published in Viruses (12-01-2022)“…γδ T cells are innate cells able to quickly eliminate pathogens or infected/tumoral cells by their antiviral and adjuvancy activities. The role of γδ T cells…”
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Expansion of Myeloid Derived Suppressor Cells Contributes to Platelet Activation by L-Arginine Deprivation during SARS-CoV-2 Infection
Published in Cells (Basel, Switzerland) (17-08-2021)“…Massive platelet activation and thrombotic events characterize severe COVID-19, highlighting their critical role in SARS-CoV-2-induced immunopathology. Since…”
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Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection
Published in The Journal of experimental medicine (29-08-2011)“…Extracellular adenosine triphosphate (ATP) can activate purinergic receptors of the plasma membrane and modulate multiple cellular functions. We report that…”
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Human Zika infection induces a reduction of IFN-γ producing CD4 T-cells and a parallel expansion of effector Vδ2 T-cells
Published in Scientific reports (24-07-2017)“…The definition of the immunological response to Zika (ZIKV) infection in humans represents a key issue to identify protective profile useful for vaccine…”
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The Plasticity of γδ T Cells: Innate Immunity, Antigen Presentation and New Immunotherapy
Published in Cellular & molecular immunology (01-06-2008)“…Several signals influence dendritic cell (DC) functions and consequent the immune responses to infectious pathogens. Our recent findings provide a new model of…”
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PMN-MDSC Frequency Discriminates Active Versus Latent Tuberculosis and Could Play a Role in Counteracting the Immune-Mediated Lung Damage in Active Disease
Published in Frontiers in immunology (26-04-2021)“…Tuberculosis (TB), due to infection, is still the principal cause of death caused by a single infectious agent. The balance between the bacillus and host…”
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Coordinated innate and T-cell immune responses in mild COVID-19 patients from household contacts of COVID-19 cases during the first pandemic wave
Published in Frontiers in immunology (27-07-2022)“…Objective To better define the immunopathogenesis of COVID-19, the present study aims to characterize the early immune responses to SARS-CoV-2 infection in…”
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IL-18 and Stem Cell Factor affect hematopoietic progenitor cells in HIV-infected patients treated during primary HIV infection
Published in Cytokine (Philadelphia, Pa.) (01-03-2018)“…[Display omitted] •ART in primary HIV infection restores the decline of lymphoid progenitors.•ART in primary HIV infection induces a decrease of IL-18 and an…”
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Different features of Vδ2 T and NK cells in fatal and non-fatal human Ebola infections
Published in PLoS neglected tropical diseases (30-05-2017)“…Human Ebola infection is characterized by a paralysis of the immune system. A signature of αβ T cells in fatal Ebola infection has been recently proposed,…”
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Myeloid Derived Suppressor Cells Expansion Persists After Early ART and May Affect CD4 T Cell Recovery
Published in Frontiers in immunology (08-08-2019)“…Myeloid-derived suppressor cells (MDSC) are expanded during HIV-1 infection and correlated with disease progression. MDSC expand in the early phase of primary…”
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Use of Pembrolizumab for Treatment of Progressive Multifocal Leukoencephalopathy in People Living with HIV
Published in Viruses (05-05-2022)“…Progressive Multifocal Leukoencephalopathy (PML) is a demyelinating disease occurring in advanced HIV infection, caused by the reactivation of poliomavirus JC…”
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Primary and Chronic HIV Infection Differently Modulates Mucosal Vδ1 and Vδ2 T-Cells Differentiation Profile and Effector Functions
Published in PloS one (18-06-2015)“…Gut-associated immune system has been identified as a major battlefield during the early phases of HIV infection. γδ T-cells, deeply affected in number and…”
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