Search Results - "Case, C. C."
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Understanding nanoparticle cellular entry: A physicochemical perspective
Published in Advances in colloid and interface science (01-04-2015)“…Understanding interactions between nanoparticles (NPs) with biological matter, particularly cells, is becoming increasingly important due to their growing…”
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2
Multi-mode strain and curvature sensors for soft robotic applications
Published in Sensors and actuators. A. Physical. (01-01-2017)“…•A sensor module capable of measuring strain and curvature is proposed.•The module is made of silicone elastomer embedded with liquid metal sensing elements.•A…”
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3
Nanoparticle-induced neuronal toxicity across placental barriers is mediated by autophagy and dependent on astrocytes
Published in Nature nanotechnology (01-05-2018)“…The potential for maternal nanoparticle (NP) exposures to cause developmental toxicity in the fetus without the direct passage of NPs has previously been…”
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4
Artificial Intelligence for Breast Cancer Risk Assessment
Published in The Radiologic clinics of North America (01-07-2024)“…Breast cancer risk prediction models based on common clinical risk factors are used to identify women eligible for high-risk screening and prevention…”
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5
A Systematic Comparison of the Actual, Potential, and Theoretical Health Effects of Cobalt and Chromium Exposures from Industry and Surgical Implants
Published in Critical reviews in toxicology (01-01-2008)“…Humans are exposed to cobalt (Co) and chromium (Cr) from industry and surgical devices, most notably orthopedic joint replacements. This review compares the…”
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Sex-Specific Effects of Nanoparticle-Encapsulated MitoQ (nMitoQ) Delivery to the Placenta in a Rat Model of Fetal Hypoxia
Published in Frontiers in physiology (24-05-2019)“…Pregnancy complications associated with chronic fetal hypoxia have been linked to the development of adult cardiovascular disease in the offspring. Prenatal…”
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7
DNA damage signalling from the placenta to foetal blood as a potential mechanism for childhood leukaemia initiation
Published in Scientific reports (13-03-2019)“…For many diseases with a foetal origin, the cause for the disease initiation remains unknown. Common childhood acute leukaemia is thought to be caused by two…”
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8
Valproate regulates inositol synthesis by reducing expression of myo-inositol-3-phosphate synthase
Published in Scientific reports (08-09-2023)“…Inositol depletion is a hypothesized mechanism of action of mood stabilization drugs used in the treatment of bipolar disorder. It was previously reported that…”
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9
Coronary Heart Disease: Have We Reached a Plateau in Primary Prevention?
Published in Journal of the American Heart Association (09-04-2020)Get full text
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10
Maternal treatment with a placental-targeted antioxidant (MitoQ) impacts offspring cardiovascular function in a rat model of prenatal hypoxia
Published in Pharmacological research (01-08-2018)“…[Display omitted] Intrauterine growth restriction, a common consequence of prenatal hypoxia, is a leading cause of fetal morbidity and mortality with a…”
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11
Childhood temperament as a predictor of adolescent nonsuicidal self-injury
Published in Development and psychopathology (01-08-2023)“…Previous cross-sectional work has consistently found associations between neuroticism and impulsivity and nonsuicidal self-injury (NSSI). However, there are…”
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Placenta-targeted treatment with nMitoQ prevents an endothelin receptor-A pathway cardiac phenotype observed in adult male offspring exposed to hypoxia in utero
Published in American journal of physiology. Heart and circulatory physiology (01-07-2023)“…Prenatal hypoxia is associated with enhanced susceptibility to cardiac ischemia-reperfusion (I/R) injury in adult offspring, however, the mechanisms remain to…”
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13
A randomized, controlled clinical trial demonstrates improved owner-assessed cognitive function in senior dogs receiving a senolytic and NAD+ precursor combination
Published in Scientific reports (29-05-2024)“…Age-related decline in mobility and cognition are associated with cellular senescence and NAD + depletion in dogs and people. A combination of a novel NAD +…”
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14
Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development
Published in Scientific reports (22-08-2017)“…Some neuropsychiatric disease, including schizophrenia, may originate during prenatal development, following periods of gestational hypoxia and placental…”
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In vitro placenta barrier model using primary human trophoblasts, underlying connective tissue and vascular endothelium
Published in Biomaterials (01-02-2019)“…Fetal development may be compromised by adverse events at the placental interface between mother and fetus. However, it is still unclear how the communication…”
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Nanoparticle‐encapsulated antioxidant improves placental mitochondrial function in a sexually dimorphic manner in a rat model of prenatal hypoxia
Published in The FASEB journal (01-02-2021)“…Pregnancy complications associated with prenatal hypoxia lead to increased placental oxidative stress. Previous studies suggest that prenatal hypoxia can…”
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Sex-Specific Effects of Prenatal Hypoxia and a Placental Antioxidant Treatment on Cardiac Mitochondrial Function in the Young Adult Offspring
Published in International journal of molecular sciences (01-09-2023)“…Prenatal hypoxia is associated with placental oxidative stress, leading to impaired fetal growth and an increased risk of cardiovascular disease in the adult…”
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Non–ST‐Segment–Elevation Myocardial Infarction: When Is Rapid Revascularization Critical?
Published in Journal of the American Heart Association (05-10-2021)Get full text
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Placental treatment improves cardiac tolerance to ischemia/reperfusion insult in adult male and female offspring exposed to prenatal hypoxia
Published in Pharmacological research (01-03-2021)“…[Display omitted] Offspring born from complicated pregnancies are at greater risk of cardiovascular disease in adulthood. Prenatal hypoxia is a common…”
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Structural basis of mammalian glycan targeting by Vibrio cholerae cytolysin and biofilm proteins
Published in PLoS pathogens (01-02-2018)“…Vibrio cholerae is an aquatic gram-negative microbe responsible for cholera, a pandemic disease causing life-threatening diarrheal outbreaks in populations…”
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