Search Results - "Casciari, Joseph J"

Orthomolecular Oncology Review: Ascorbic Acid and Cancer 25 Years Later by González, Michael J., Miranda-Massari, Jorge R., Mora, Edna M., Guzmán, Angelik, Riordan, Neil H., Riordan, Hugh D., Casciari, Joseph J., Jackson, James A., Román-Franco, Angel

“…The effect of ascorbic acid on cancer has been a subject of great controversy. This is a follow-up review of the 1979 article by Cameron, Pauling, and…”
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Effect of weight reduction on cardiovascular risk factors and CD34-positive cells in circulation by Mikirova, Nina A, Casciari, Joseph J, Hunninghake, Ronald E, Beezley, Margaret M

“…Being overweight or obese is associated with an increased risk for the development of non-insulin-dependent diabetes mellitus, hypertension, and cardiovascular…”
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Ascorbate inhibition of angiogenesis in aortic rings ex vivo and subcutaneous Matrigel plugs in vivo by Mikirova, Nina A, Casciari, Joseph J, Riordan, Neil H

“…Angiogenesis is critical to tumor growth and is therefore a potential target for cancer therapy. As many current inhibitors of angiogenesis exhibit host…”
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A pilot clinical study of continuous intravenous ascorbate in terminal cancer patients by Riordan, Hugh D, Casciari, Joseph J, González, Michael J, Riordan, Neil H, Miranda-Massari, Jorge R, Taylor, Paul, Jackson, James A

“…Case studies suggest that vitamin C, given intravenously at doses of 10-100 grams/day can improve patient well being and in some cases, reduce tumor size…”
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Vitamin C Pharmacokinetics after Continuous Infusion in a Patient with Prostate Cancer by Duconge, Jorge, Miranda-Massari, Jorge R, González, Michael J, Taylor, Paul R, Riordan, Hugh D, Riordan, Neil H, Casciari, Joseph J, Alliston, Kevin

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Effects of high dose ascorbate administration on L-10 tumor growth in guinea pigs by Casciari, Joseph J, Riordan, Hugh D, Miranda-Massari, Jorge R, Gonzalez, Michael J

“…Sodium ascorbate is preferentially toxic to tumor cells at high concentrations. It has not been established, however, whether sufficient intra-tumor ascorbate…”
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Intravenous vitamin C as a chemotherapy agent: a report on clinical cases by Riordan, Hugh D, Riordan, Neil H, Jackson, James A, Casciari, Joseph J, Hunninghake, Ron, González, Michael J, Mora, Edna M, Miranda-Massari, Jorge R, Rosario, Norberto, Rivera, Alfredo

“…A series of seven cases are presented in which intravenous vitamin C has been used as antineoplastic agent in the treatment of different types of cancers. The…”
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Intravenous ascorbic acid: protocol for its application and use by Riordan, Hugh D, Hunninghake, Ronald B, Riordan, Neil H, Jackson, James J, Meng, Xiaolong, Taylor, Paul, Casciari, Joseph J, González, Michael J, Miranda-Massari, Jorge R, Mora, Edna M, Rosario, Norberto, Rivera, Alfredo

“…High dose intravenous(i.v.) ascorbic acid (AA) has been used as therapy for infectious disease from bacterial and viral origin and adjuvant therapy for cancer…”
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Effects of a high molecular mass Convolvulus arvensis extract on tumor growth and angiogenesis by Meng, Xiao Long, Riordan, Neil H, Casciari, Joseph J, Zhu, Yan, Zhong, Jie, González, Michael J, Miranda-Massari, Jorge R, Riordan, Hugh D

“…Plant materials represent promising sources of anti-cancer agents. We developed and tested a novel extract from the ubiquitous plant Convolvulus arvensis…”
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Growth and chemotherapeutic response of cells in a hollow-fiber in vitro solid tumor model by Casciari, J J, Hollingshead, M G, Alley, M C, Mayo, J G, Malspeis, L, Miyauchi, S, Grever, M R, Weinstein, J N

“…Cancer treatments that appear promising in tissue culture are often less effective in solid tumors, in part because of the proliferative and microenvironmental…”
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Glucose diffusivity in multicellular tumor spheroids by CASCIARI, J. J, SOTIRCHOS, S. V, SUTHERLAND, R. M

“…In order to understand the role of glucose limitations in controlling multicellular tumor spheroid growth, knowledge of the glucose diffusion coefficient is…”
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Orthomolecular oncology: a mechanistic view of intravenous ascorbate's chemotherapeutic activity by González, Michael J, Miranda-Massari, Jorge R, Mora, Edna M, Jiménez, Ivonne Z, Matos, María Isabel, Riordan, Hugh D, Casciari, Joseph J, Riordan, Neil H, Rodríguez, Marielys, Guzmán, Angelik

“…The effect of vitamin C in cancer has been a subject of great controversy; mainly because of the inconsistent results obtained by oral intakes of ascorbate…”
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Variations in tumor cell growth rates and metabolism with oxygen concentration, glucose concentration, and extracellular pH by Casciari, J J, Sotirchos, S V, Sutherland, R M

“…Tumors and multicellular tumor spheroids can develop gradients in oxygen concentration, glucose concentration, and extracellular pH as they grow. In order to…”
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Determining Hypoxic Fraction in a Rat Glioma by Uptake of Radiolabeled Fluoromisonidazole by Rasey, Janet S., Casciari, Joseph J., Hofstrand, Philip D., Muzi, Mark, Graham, Michael M., Chin, Lay K.

“…Rasey, J.S., Casciari, J.J., Hofstrand, P.D., Muzi, M., Graham, M.M. and Chin, L.K. Determining the Hypoxic Fraction in a Rat Glioma by Uptake of Radiolabeled…”
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Noninvasive Detection of Hypoxic Myocardium Using Fluorine-18-Fluoromisonidazole and Positron Emission Tomography by Martin, Gary V, Caldwell, James H, Graham, Michael M, Grierson, John R, Kroll, Keith, Cowan, Marie J, Lewellen, Thomas K, Rasey, Janet S, Casciari, Joseph J, Krohn, Kenneth A

“…Fluoromisonidazole (FMISO) is metabolically trapped in viable cells as a function of reduced cellular pO2. Therefore [18F]-FMISO is potentially useful for…”
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Vitamin C pharmacokinetics after continuous infusion in a patient with prostate cancer by Duconge, Jorge, Miranda-Massari, Jorge R, González, Michael J, Taylor, Paul R, Riordan, Hugh D, Riordan, Neil H, Casciari, Joseph J, Alliston, Kevin

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