Search Results - "Casavant, T"

An Analysis of Allelic Variation in the ABCA4 Gene by Webster, Andrew R, Heon, Elise, Lotery, Andrew J, Vandenburgh, Kimberlie, Casavant, Thomas L, Oh, Kean T, Beck, Gretel, Fishman, Gerald A, Lam, Byron L, Levin, Alex, Heckenlively, John R, Jacobson, Samuel G, Weleber, Richard G, Sheffield, Val C, Stone, Edwin M

“…To assess the allelic variation of the ATP-binding transporter protein (ABCA4). A combination of single-strand conformation polymorphism (SSCP) and automated…”
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Missense Variations in the Fibulin 5 Gene and Age-Related Macular Degeneration by Stone, Edwin M, Braun, Terry A, Russell, Stephen R, Kuehn, Markus H, Lotery, Andrew J, Moore, Paula A, Eastman, Christopher G, Casavant, Thomas L, Sheffield, Val C

“…Age-related macular degeneration (AMD) is common, affecting approximately 7 million people in the United States. However, knowledge of its causes is scant…”
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Discovery of Five Conserved β-Defensin Gene Clusters Using a Computational Search Strategy by Schutte, Brian C., Mitros, Joseph P., Bartlett, Jennifer A., Walters, Jesse D., Jia, Hong Peng, Welsh, Michael J., Casavant, Thomas L., McCray, Paul B.

“…The innate immune system includes antimicrobial peptides that protect multicellular organisms from a diverse spectrum of microorganisms. β-Defensins comprise…”
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Migration of the Plastid Genome to the Nucleus in a Peridinin Dinoflagellate by Hackett, Jeremiah D., Yoon, Hwan Su, Soares, M. Bento, Bonaldo, Maria F., Casavant, Thomas L., Scheetz, Todd E., Nosenko, Tetyana, Bhattacharya, Debashish

“…Dinoflagellate algae are important primary producers and of significant ecological and economic impact because of their ability to form “red tides”[1]. They…”
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A taxonomy of scheduling in general-purpose distributed computing systems by Casavant, T.L., Kuhl, J.G.

“…One measure of the usefulness of a general-purpose distributed computing system is the system's ability to provide a level of performance commensurate to the…”
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Pooled library tissue tags for EST-based gene discovery by Gavin, A. J., Scheetz, T. E., Roberts, C. A., O'Leary, B., Braun, T. A., Sheffield, V. C., Soares, M. B., Robinson, J. P., Casavant, T. L.

“…Motivation: In gene discovery projects based on EST sequencing, effective post-sequencing identification methods are important in determining tissue sources of…”
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Anopheles gambiae Pilot Gene Discovery Project: Identification of Mosquito Innate Immunity Genes from Expressed Sequence Tags Generated from Immune-Competent Cell Lines by Dimopoulos, George, Casavant, Thomas L., Chang, Shereen, Scheetz, Todd, Roberts, Chad, Donohue, Micca, Schultz, Jorg, Benes, Vladimir, Bork, Peer, Ansorge, Wilhelm, Soares, Marcelo Bento, Kafatos, Fotis C.

“…Together with AIDS and tuberculosis, malaria is at the top of the list of devastating infectious diseases. However, molecular genetic studies of its major…”
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Gene expression profiling of potential PPARγ target genes in mouse aorta by Keen, Henry L., Ryan, Michael J., Beyer, Andreas, Mathur, Satya, Scheetz, Todd E., Gackle, Barry D., Faraci, Frank M., Casavant, Thomas L., Sigmund, Curt D.

“…Diminished activity of peroxisome proliferator-activated receptor-γ (PPARγ) may play a role in the pathogenesis of hypertension and vascular dysfunction. To…”
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Genomics-based approaches to gene discovery in innate immunity by Scheetz, Todd, Bartlett, Jennifer A., Walters, Jesse D., Schutte, Brian C., Casavant, Thomas L., B. McCray Jr, Paul

“…The completion of draft sequences of the human and mouse genomes offers many opportunities for gene discovery in the field of immunology through the…”
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Parallelization of local BLAST service on workstation clusters by Braun, R.C, Pedretti, K.T, Casavant, T.L, Scheetz, T.E, Birkett, C.L, Roberts, C.A

“…This paper describes approaches to improve the performance of one of the most common and increasingly important aspects of the Human Genome Project (HGP) —…”
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ESTprep: preprocessing cDNA sequence reads by Scheetz, Todd E., Trivedi, Nishank, Roberts, Chad A., Kucaba, Tamara, Berger, Brian, Robinson, Natalie L., Birkett, Clayton L., Gavin, Allen J., O’Leary, Brian, Braun, Terry A., Bonaldo, Maria F., Robinson, John P., Sheffield, Val C., Soares, Marcelo B., Casavant, Thomas L.

“…Motivation: High accuracy of data always governs the large-scale gene discovery projects. The data should not only be trustworthy but should be correctly…”
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Automated construction of high-density comparative maps between rat, human, and mouse by Kwitek, A E, Tonellato, P J, Chen, D, Gullings-Handley, J, Cheng, Y S, Twigger, S, Scheetz, T E, Casavant, T L, Stoll, M, Nobrega, M A, Shiozawa, M, Soares, M B, Sheffield, V C, Jacob, H J

“…Animal models have been used primarily as surrogates for humans, having similar disease-based phenotypes. Genomic organization also tends to be conserved…”
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PLET1 ( C11orf34), a highly expressed and processed novel gene in pig and mouse placenta, is transcribed but poorly spliced in human by Zhao, Shu-Hong, Simmons, David G., Cross, James C., Scheetz, Todd E., Casavant, Thomas L., Soares, M.Bento, Tuggle, Christopher K.

“…Sequencing of porcine cDNAs identified a novel EST with high frequency in placenta tissue. Full-length PLET1 (placenta-expressed transcript 1, also called…”
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Large-scale gene discovery in human airway epithelia reveals novel transcripts by Scheetz, Todd E, Zabner, Joseph, Welsh, Michael J, Coco, Justin, Eyestone, Mari, de Fatima Bonaldo, Maria, Kucaba, Tamara, Casavant, Thomas L, Soares, M. Bento, McCray, Paul B., Jr

“…1 Departments of Pediatrics 2 Internal Medicine 3 Ophthalmology 4 Electrical and Computer Engineering 5 Biomedical Engineering 6 Center for Bioinformatics and…”
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Gene transcript clustering: a comparison of parallel approaches by Scheetz, Todd E., Trivedi, Nishank, Pedretti, Kevin T., Braun, Terry A., Casavant, Thomas L.

“…One of the fundamental components of large-scale gene discovery projects is that of clustering of expressed sequence tags (ESTs) from complementary DNA (cDNA)…”
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Bardet-Biedl Syndrome Type 4 (BBS4)-Null Mice Implicate Bbs4 in Flagella Formation but Not Global Cilia Assembly by Mykytyn, Kirk, Mullins, Robert F., Andrews, Michael, Chiang, Annie P., Swiderski, Ruth E., Yang, Baoli, Braun, Terry, Casavant, Thomas, Stone, Edwin M., Sheffield, Val C., Nathans, Jeremy

“…The functions of the proteins encoded by the Bardet-Biedl syndrome (BBS) genes are unknown. Mutations in these genes lead to the pleiotropic human disorder…”
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Specification and analysis of parallel/distributed software and systems by Petri nets with transition enabling functions by Papelis, Y.E., Casavant, T.L.

“…An approach for visually specifying parallel/distributed software using Petri nets (PNs) extend with transition enabling functions (TEFs) is investigated. The…”
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Comparative Genomic Analysis Identifies an ADP-Ribosylation Factor–like Gene as the Cause of Bardet-Biedl Syndrome (BBS3) by Chiang, Annie P., Nishimura, Darryl, Searby, Charles, Elbedour, Khalil, Carmi, Rivka, Ferguson, Amanda L., Secrist, Jenifer, Braun, Terry, Casavant, Thomas, Stone, Edwin M., Sheffield, Val C.

“…Bardet-Biedl syndrome (BBS) is a genetically heterogeneous, pleiotropic human disorder characterized by obesity, retinopathy, polydactyly, renal and cardiac…”
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Perspectives on high performance network computing by Strumpen, V, Ramkumar, B, Casavant, T.L, Reddy, S.M

“…Networks of workstations have become increasingly popular for high performance computing. However, in order to become a real alternative for Massively Parallel…”
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Effects of response and stability on scheduling in distributed computing systems by Casavant, T.L., Kuhl, J.G.

“…An examination is made of the effects of response and stability on scheduling algorithms for general-purpose distributed computing systems. Response…”
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