Search Results - "Casas, Francois"
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Coactivation of nuclear receptors and myogenic factors induces the major BTG1 influence on muscle differentiation
Published in Oncogene (03-03-2005)“…The btg1 (B-cell translocation gene 1) gene coding sequence was isolated from a translocation break point in a case of B-cell chronic lymphocytic leukaemia. We…”
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2
Toxicity of Natural Deep Eutectic Solvent Betaine:Glycerol in Rats
Published in Journal of agricultural and food chemistry (20-06-2018)“…Natural deep eutectic solvents (NaDES) are new natural solvents in green chemistry that in some cases have been shown to allow better extraction of plant…”
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3
E2F transcription factor-1 regulates oxidative metabolism
Published in Nature cell biology (01-09-2011)“…Cells respond to stress by coordinating proliferative and metabolic pathways. Starvation restricts cell proliferative (glycolytic) and activates energy…”
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4
Oxidative stress, inflammation, and autophagic stress as the key mechanisms of premature age-related hearing loss in SAMP8 mouse Cochlea
Published in Antioxidants & redox signaling (01-02-2012)“…In our aging society, age-related hearing loss (ARHL) or presbycusis is increasingly important. Here, we study the mechanism of ARHL using the…”
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5
Potential physio-pathological effects of branched fatty acid esters of hydroxy fatty acids
Published in Biochimie (01-03-2021)“…Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) are a new endogenous lipid class with recently uncovered interesting biological effects and which…”
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6
Mitochondrial T3 receptor and targets
Published in Molecular and cellular endocrinology (15-12-2017)“…The demonstration that TRα1 mRNA encodes a nuclear thyroid hormone receptor and two proteins imported into mitochondria with molecular masses of 43 and 28 kDa…”
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7
Dietary omega 3 fatty acids and skeletal muscle metabolism: a review of clinical and preclinical studies
Published in Oléagineux corps gras lipides (01-07-2024)“…Background : There is a myriad of metabolic roles of omega-3 fatty acids. More recently, studies have looked at omega-3 fatty acids effects on skeletal muscle…”
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Long-term intake of 9-PAHPA or 9-OAHPA modulates favorably the basal metabolism and exerts an insulin sensitizing effect in obesogenic diet-fed mice
Published in European journal of nutrition (01-06-2021)“…Purpose Fatty acid esters of hydroxy fatty acids (FAHFAs) are a large family of endogenous bioactive lipids. To date, most of the studied FAHFAs are branched…”
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9
A single short reprogramming early in life initiates and propagates an epigenetically related mechanism improving fitness and promoting an increased healthy lifespan
Published in Aging cell (01-11-2022)“…Recent advances in cell reprogramming showed that OSKM induction is able to improve cell physiology in vitro and in vivo. Here, we show that a single short…”
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10
Preventive nutritional supplementation with furan fatty acid in a DIO mouse model increases muscle mass and reduces metabolic disorders
Published in Biomedicine & pharmacotherapy (01-08-2023)“…The increase in obesity has become a major global health problem and is associated with numerous metabolic dysfunctions. Furan fatty acids (FuFAs) are minor…”
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Furan fatty acid extracted from Hevea brasiliensis latex increases muscle mass in mice
Published in Biomedicine & pharmacotherapy (01-10-2023)“…Skeletal muscle is essential for locomotion and plays a crucial role in energy homeostasis. It is regulated by nutrition, genetic factors, physical activity…”
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12
ROS-Induced Activation of DNA Damage Responses Drives Senescence-Like State in Postmitotic Cochlear Cells: Implication for Hearing Preservation
Published in Molecular neurobiology (01-08-2019)“…In our aging society, age-related hearing loss (ARHL) has become a major socioeconomic issue. Reactive oxygen species (ROS) may be one of the main causal…”
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13
p43, a Truncated Form of Thyroid Hormone Receptor α, Regulates Maturation of Pancreatic β Cells
Published in International journal of molecular sciences (01-03-2021)“…P43 is a truncated form of thyroid hormone receptor α localized in mitochondria, which stimulates mitochondrial respiratory chain activity. Previously, we…”
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Long‐Term Measures of Dyslipidemia, Inflammation, and Oxidative Stress in Rats Fed a High‐Fat/High‐Fructose Diet
Published in Lipids (01-01-2019)“…Inflammation and oxidative stress are thought to be involved in, or associated with, the development of obesity, dyslipidemia, hepatic steatosis, and insulin…”
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Chicoric acid is an antioxidant molecule that stimulates AMP kinase pathway in L6 myotubes and extends lifespan in Caenorhabditis elegans
Published in PloS one (11-11-2013)“…Chicoric acid (CA) is a caffeoyl derivative previously described as having potential anti-diabetic properties. As similarities in cellular mechanism…”
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16
Exacerbated age-related hearing loss in mice lacking the p43 mitochondrial T3 receptor
Published in BMC biology (01-02-2021)“…Age-related hearing loss (ARHL), also known as presbycusis, is the most common sensory impairment seen in elderly people. However, the cochlear aging process…”
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17
Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53
Published in Molecular cell (15-02-2018)“…Accumulating evidence indicates that the MDM2 oncoprotein promotes tumorigenesis beyond its canonical negative effects on the p53 tumor suppressor, but these…”
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FAHFAs Regulate the Proliferation of C2C12 Myoblasts and Induce a Shift toward a More Oxidative Phenotype in Mouse Skeletal Muscle
Published in International journal of molecular sciences (01-12-2020)“…Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are endogenous lipids reported to have antidiabetic and anti-inflammatory effects. Since skeletal…”
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Long-term high intake of 9-PAHPA or 9-OAHPA increases basal metabolism and insulin sensitivity but disrupts liver homeostasis in healthy mice
Published in The Journal of nutritional biochemistry (01-05-2020)“…Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are a new family of endogenous lipids recently discovered. Several studies reported that some FAHFAs…”
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Time-of-Day Circadian Modulation of Grape-Seed Procyanidin Extract (GSPE) in Hepatic Mitochondrial Dynamics in Cafeteria-Diet-Induced Obese Rats
Published in Nutrients (12-02-2022)“…Major susceptibility to alterations in liver function (e.g., hepatic steatosis) in a prone environment due to circadian misalignments represents a common…”
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