Search Results - "Casarotto, C."

Psychedelics promote plasticity by directly binding to BDNF receptor TrkB by Moliner, Rafael, Girych, Mykhailo, Brunello, Cecilia A., Kovaleva, Vera, Biojone, Caroline, Enkavi, Giray, Antenucci, Lina, Kot, Erik F., Goncharuk, Sergey A., Kaurinkoski, Katja, Kuutti, Mirjami, Fred, Senem M., Elsilä, Lauri V., Sakson, Sven, Cannarozzo, Cecilia, Diniz, Cassiano R. A. F., Seiffert, Nina, Rubiolo, Anna, Haapaniemi, Hele, Meshi, Elsa, Nagaeva, Elina, Öhman, Tiina, Róg, Tomasz, Kankuri, Esko, Vilar, Marçal, Varjosalo, Markku, Korpi, Esa R., Permi, Perttu, Mineev, Konstantin S., Saarma, Mart, Vattulainen, Ilpo, Casarotto, Plinio C., Castrén, Eero

“…Psychedelics produce fast and persistent antidepressant effects and induce neuroplasticity resembling the effects of clinically approved antidepressants. We…”
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Opposing Roles for Cannabinoid Receptor Type-1 (CB ) and Transient Receptor Potential Vanilloid Type-1 Channel (TRPV1) on the Modulation of Panic-Like Responses in Rats by Casarotto, Plínio C, Terzian, Ana Luisa B, Aguiar, Daniele C, Zangrossi, Hélio, Guimarães, Francisco S, Wotjak, Carsten T, Moreira, Fabrício A

“…The midbrain dorsal periaqueductal gray (dPAG) has an important role in orchestrating anxiety- and panic-related responses. Given the cellular and behavioral…”
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Nitric Oxide Synthase inhibition counteracts the stress‐induced DNA methyltransferase 3b expression in the hippocampus of rats by Sousa Maciel, Izaque, Sales, Amanda J., Casarotto, Plinio C., Castrén, Eero, Biojone, Caroline, Joca, Sâmia R. L.

“…It has been postulated that the activation of NMDA receptors (NMDAr) and nitric oxide (NO) production in the hippocampus is involved in the behavioral…”
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Vanishing permanent glaciers: climate change is threatening a European Union habitat (Code 8340) and its poorly known biodiversity by Gobbi, M., Ambrosini, R., Casarotto, C., Diolaiuti, G., Ficetola, G. F., Lencioni, V., Seppi, R., Smiraglia, C., Tampucci, D., Valle, B., Caccianiga, M.

“…The cryosphere (i.e. glaciers and permafrost) and its related landforms offer a wide range of ecosystem services, thus they have strong relationships with…”
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USE OF HISTORICAL AERIAL IMAGES FOR 3D MODELLING OF GLACIERS IN THE PROVINCE OF TRENTO by Poli, D., Casarotto, C., Strudl, M., Bollmann, E., Moe, K., Legat, K.

“…Historical aerial images represent a source of information of great value for glacier monitoring, as they cover the area of interest at a well-defined epoch…”
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Monoamine involvement in the antidepressant-like effect induced by P2 blockade by Diniz, Cassiano R.A.F., Rodrigues, Murilo, Casarotto, Plínio C., Pereira, Vítor S., Crestani, Carlos C., Joca, Sâmia R.L.

“…•Combined sub-effective doses of PPADS and fluoxetine yield antidepressant-like effect.•Combined sub-effective doses of PPADS and reboxetine yield…”
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NMDA-NO signaling in the dorsal and ventral hippocampus time-dependently modulates the behavioral responses to forced swimming stress by Diniz, Cassiano R.A.F., Casarotto, Plínio C., Joca, Sâmia R.L.

“…•Hippocampal synaptic transmission inactivation does not affect swimming behavior.•Blocking NMDA-NO system into dorsal hippocampus promote antidepressant-like…”
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Decay of a long-term monitored glacier: Careser Glacier (Ortles-Cevedale, European Alps) by Carturan, L, Baroni, C, Becker, M, Bellin, A, Cainelli, O, Carton, A, Casarotto, C, Dalla Fontana, G, Godio, A, Martinelli, T, Salvatore, M. C, Seppi, R

“…The continuation of valuable, long-term glacier observation series is threatened by the accelerated mass loss which currently affects a large portion of…”
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Facilitation of TRKB Activation by the Angiotensin II Receptor Type-2 (AT2R) Agonist C21 by Laukkanen, Liina, Diniz, Cassiano R. A. F., Foulquier, Sebastien, Prickaerts, Jos, Castrén, Eero, Casarotto, Plinio C.

“…Blockers of angiotensin II type 1 receptor (AT1R) exert antidepressant-like effects by indirectly facilitating the activation of the angiotensin II type 2…”
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Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors by Casarotto, Plinio C, Gomes, Felipe V, Resstel, Leonardo B.M, Guimarães, Francisco S

“…Cannabidiol (CBD) is a major nonpsychotomimetic component of Cannabis sativa that has been shown to have an anxiolytic effect in human and animal models…”
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Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors by Diniz, Cassiano R A F, Biojone, Caroline, Joca, Samia R L, Rantamäki, Tomi, Castrén, Eero, Guimarães, Francisco S, Casarotto, Plinio C

“…Administration of anandamide (AEA) or 2-arachidonoylglycerol (2AG) induces CB1 coupling and activation of TRKB receptors, regulating the neuronal migration and…”
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Reduced P2X receptor levels are associated with antidepressant effect in the learned helplessness model by Ribeiro, Deidiane Elisa, Casarotto, Plinio C, Staquini, Laura, Pinto e Silva, Maria Augusta, Biojone, Caroline, Wegener, Gregers, Joca, Samia

“…Purinergic receptors, especially P2RX, are associated to the severity of symptoms in patients suffering from depressive and bipolar disorders, and genetic…”
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Inducible nitric oxide synthase (NOS2) knockout mice as a model of trichotillomania by Casarotto, Plinio C, Biojone, Caroline, Montezuma, Karina, Cunha, Fernando Q, Joca, Samia R L, Castren, Eero, Guimaraes, Francisco S

“…Trichotillomania (TTM) is an impulse control disorder characterized by repetitive hair pulling/trimming. Barbering behavior (BB) observed in laboratory animals…”
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Anti-aversive effects of the atypical antipsychotic, aripiprazole, in animal models of anxiety by Biojone, Caroline, Casarotto, Plínio C, Resstel, Leonardo B, Zangrossi, Hélio, Guimarães, Francisco S, Moreira, Fabrício A

“…Aripiprazole is a unique antipsychotic that seems to act as a partial agonist at dopamine D2-receptors, contrasting with other drugs in this class, which are…”
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Antidepressant drugs act by directly binding to TRKB neurotrophin receptors by Casarotto, Plinio C., Girych, Mykhailo, Fred, Senem M., Kovaleva, Vera, Moliner, Rafael, Enkavi, Giray, Biojone, Caroline, Cannarozzo, Cecilia, Sahu, Madhusmita Pryiadrashini, Kaurinkoski, Katja, Brunello, Cecilia A., Steinzeig, Anna, Winkel, Frederike, Patil, Sudarshan, Vestring, Stefan, Serchov, Tsvetan, Diniz, Cassiano R.A.F., Laukkanen, Liina, Cardon, Iseline, Antila, Hanna, Rog, Tomasz, Piepponen, Timo Petteri, Bramham, Clive R., Normann, Claus, Lauri, Sari E., Saarma, Mart, Vattulainen, Ilpo, Castrén, Eero

“…It is unclear how binding of antidepressant drugs to their targets gives rise to the clinical antidepressant effect. We discovered that the transmembrane…”
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The antimanic-like effect of phenytoin and carbamazepine on methylphenidate-induced hyperlocomotion: role of voltage-gated sodium channels by Tonelli, Denise A.G., Pereira, Marcela, Siba, Isadora P., Martynhak, Bruno J., Correia, Diego, Casarotto, Plínio C., Biojone, Caroline, Guimarães, Francisco S., Joca, Samia L.R., Andreatini, Roberto

“…The objective of this study was to verify whether phenytoin modifies methylphenidate‐induced hyperlocomotion, an animal model for screening antimanic‐like…”
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Intrahippocampal injection of brain-derived neurotrophic factor increases anxiety-related, but not panic-related defensive responses: involvement of serotonin by Casarotto, Plinio C, de Bortoli, Valquiria C, Zangrossi, Hélio

“…Changes in brain-derived neurotrophic factor (BDNF)-mediated signaling in the hippocampus have been implicated in the etiology of depression and in the mode of…”
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Beyond good and evil: A putative continuum-sorting hypothesis for the functional role of proBDNF/BDNF-propeptide/mBDNF in antidepressant treatment by Diniz, Cassiano R.A.F., Casarotto, Plinio C, Resstel, Leonardo, Joca, Sâmia R.L.

“…•Stress and antidepressants modulate brain neuroplasticity and BDNF levels.•BDNF production is tied to previous proBDNF making.•Binary sorting hypothesis…”
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Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2 by Fred, Senem Merve, Laukkanen, Liina, Brunello, Cecilia A., Vesa, Liisa, Göös, Helka, Cardon, Iseline, Moliner, Rafael, Maritzen, Tanja, Varjosalo, Markku, Casarotto, Plinio C., Castrén, Eero

“…Several antidepressant drugs activate tropomyosin-related kinase B (TRKB) receptor, but it remains unclear whether these compounds employ a common mechanism…”
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Cholesterol‐recognition motifs in the transmembrane domain of the tyrosine kinase receptor family: The case of TRKB by Cannarozzo, Cecilia, Fred, Senem Merve, Girych, Mykhailo, Biojone, Caroline, Enkavi, Giray, Róg, Tomasz, Vattulainen, Ilpo, Casarotto, Plinio C, Castrén, Eero

“…Cholesterol is an essential constituent of cell membranes. The discovery of cholesterol‐recognition amino acid consensus (CRAC) motif in proteins indicated a…”
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