Search Results - "Casarini, Livio"

Molecular Mechanisms of Action of FSH by Casarini, Livio, Crépieux, Pascale

“…The glycoprotein follicle-stimulating hormone (FSH) acts on gonadal target cells, hence regulating gametogenesis. The transduction of the hormone-induced…”
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Two Hormones for One Receptor: Evolution, Biochemistry, Actions, and Pathophysiology of LH and hCG by Casarini, Livio, Santi, Daniele, Brigante, Giulia, Simoni, Manuela

“…Abstract LH and chorionic gonadotropin (CG) are glycoproteins fundamental to sexual development and reproduction. Because they act on the same receptor…”
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Prospects for FSH Treatment of Male Infertility by Simoni, Manuela, Brigante, Giulia, Rochira, Vincenzo, Santi, Daniele, Casarini, Livio

“…Abstract Context Despite the new opportunities provided by assisted reproductive technology (ART), male infertility treatment is far from being optimized. One…”
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Efficacy of Follicle-Stimulating Hormone (FSH) Alone, FSH + Luteinizing Hormone, Human Menopausal Gonadotropin or FSH + Human Chorionic Gonadotropin on Assisted Reproductive Technology Outcomes in the "Personalized" Medicine Era: A Meta-analysis by Santi, Daniele, Casarini, Livio, Alviggi, Carlo, Simoni, Manuela

“…Luteinizing hormone (LH) and human chorionic gonadotropin (hCG) act on the same receptor, activating different signal transduction pathways. The role of LH or…”
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LH and hCG action on the same receptor results in quantitatively and qualitatively different intracellular signalling by Casarini, Livio, Lispi, Monica, Longobardi, Salvatore, Milosa, Fabiola, La Marca, Antonio, Tagliasacchi, Daniela, Pignatti, Elisa, Simoni, Manuela

“…Human luteinizing hormone (hLH) and chorionic gonadotropin (hCG) act on the same receptor (LHCGR) but it is not known whether they elicit the same cellular and…”
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Allosteric modulation of gonadotropin receptors by Lazzaretti, Clara, Simoni, Manuela, Casarini, Livio, Paradiso, Elia

“…Gonadotropins regulate reproductive functions by binding to G protein-coupled receptors (FSHR and LHCGR) expressed in the gonads. They activate multiple,…”
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FSH for the Treatment of Male Infertility by Casarini, Livio, Crépieux, Pascale, Reiter, Eric, Lazzaretti, Clara, Paradiso, Elia, Rochira, Vincenzo, Brigante, Giulia, Santi, Daniele, Simoni, Manuela

“…Follicle-stimulating hormone (FSH) supports spermatogenesis acting via its receptor (FSHR), which activates trophic effects in gonadal Sertoli cells. These…”
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Human Luteinizing Hormone and Chorionic Gonadotropin Display Biased Agonism at the LH and LH/CG Receptors by Riccetti, Laura, Yvinec, Romain, Klett, Danièle, Gallay, Nathalie, Combarnous, Yves, Reiter, Eric, Simoni, Manuela, Casarini, Livio, Ayoub, Mohammed Akli

“…Human luteinizing hormone (LH) and chorionic gonadotropin (hCG) have been considered biologically equivalent because of their structural similarities and their…”
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Editorial: Follicle-stimulating hormone: Fertility and beyond-volume II by Simoni, Manuela, Huhtaniemi, Ilpo, Casarini, Livio, Santi, Daniele

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Bitter Taste Receptors and Endocrine Disruptors: Cellular and Molecular Insights from an In Vitro Model of Human Granulosa Cells by Luongo, Francesca Paola, Passaponti, Sofia, Haxhiu, Alesandro, Raeispour, Maryam, Belmonte, Giuseppe, Governini, Laura, Casarini, Livio, Piomboni, Paola, Luddi, Alice

“…Endocrine disrupting chemicals (EDCs) are compounds that interfere with the synthesis, transport and binding action of hormones responsible for reproduction…”
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Pharmacogenetics of G-protein-coupled receptors variants: FSH receptor and infertility treatment by Santi, Daniele, Potì, Francesco, Simoni, Manuela, Casarini, Livio

“…Infertility treatment may represent a paradigmatic example of precision medicine. Follicle-stimulating hormone (FSH) has been proposed as a valuable…”
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Follicle-stimulating Hormone (FSH) Action on Spermatogenesis: A Focus on Physiological and Therapeutic Roles by Santi, Daniele, Crépieux, Pascale, Reiter, Eric, Spaggiari, Giorgia, Brigante, Giulia, Casarini, Livio, Rochira, Vincenzo, Simoni, Manuela

“…Human reproduction is regulated by the combined action of the follicle-stimulating hormone (FSH) and the luteinizing hormone (LH) on the gonads. Although FSH…”
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Regulation of antral follicular growth by an interplay between gonadotropins and their receptors by Casarini, Livio, Paradiso, Elia, Lazzaretti, Clara, D’Alessandro, Sara, Roy, Neena, Mascolo, Elisa, Zaręba, Kornelia, García-Gasca, Alejandra, Simoni, Manuela

“…Knowledge of the growth and maturation of human antral follicles is based mainly on concepts and deductions from clinical observations and animal models. To…”
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Intracellular cGMP increase is not involved in thyroid cancer cell death by Alessandro, Sara D', Paradiso, Elia, Lazzaretti, Clara, Sperduti, Samantha, Perri, Carmela, Antoniani, Francesco, Righi, Sara, Simoni, Manuela, Brigante, Giulia, Casarini, Livio

“…Type 5 phosphodiesterase (PDE5) inhibitors (PDE5i) lead to intracellular cyclic-guanosine monophosphate (cGMP) increase and are used for clinical treatment of…”
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Nuclear expression of VDR and AHR is mutually exclusive in glandular cells in endometriosis by De Pascali, Francesco, Casarini, Livio, Kuhn, Christina, Simoni, Manuela, Mahner, Sven, Jeschke, Udo, von Schönfeldt, Viktoria

“…The vitamin D receptor (VDR) and aryl hydrocarbon receptor (AHR) are two nuclear receptors that exert their effects by binding with ligands and forming a…”
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Identification of Key Receptor Residues Discriminating Human Chorionic Gonadotropin (hCG)- and Luteinizing Hormone (LH)-Specific Signaling by Lazzaretti, Clara, Secco, Valentina, Paradiso, Elia, Sperduti, Samantha, Rutz, Claudia, Kreuchwig, Annika, Krause, Gerd, Simoni, Manuela, Casarini, Livio

“…(1) The human luteinizing hormone (LH)/chorionic gonadotropin (hCG) receptor (LHCGR) discriminates its two hormone ligands and differs from the murine receptor…”
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BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting by Sorbi, Claudia, Belluti, Silvia, Atene, Claudio Giacinto, Marocchi, Federica, Linciano, Pasquale, Roy, Neena, Paradiso, Elia, Casarini, Livio, Ronsisvalle, Simone, Zanocco-Marani, Tommaso, Brasili, Livio, Lanfrancone, Luisa, Imbriano, Carol, Di Rocco, Giulia, Franchini, Silvia

“…The management of advanced-stage melanoma is clinically challenging, mainly because of its resistance to the currently available therapies. Therefore, it is…”
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Benzo[a]pyrene disrupts LH/hCG-dependent mouse Leydig cell steroidogenesis through receptor/Gαs protein targeting by Lazzaretti, Clara, Roy, Neena, Paradiso, Elia, Capponi, Chiara, Ferrari, Tommaso, Reggianini, Francesca, Sperduti, Samantha, Perri, Carmela, Baschieri, Lara, Mascolo, Elisa, Varani, Manuela, Canu, Giulia, Trenti, Tommaso, Nicoli, Alessia, Morini, Daria, Iannotti, Francesca, Villani, Maria Teresa, Vicini, Elena, Simoni, Manuela, Casarini, Livio

“…Steroidogenesis of gonadal cells is tightly regulated by gonadotropins. However, certain polycyclic aromatic hydrocarbons, including Benzo[a]pyrene (BaP),…”
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Polymorphisms in gonadotropin and gonadotropin receptor genes as markers of ovarian reserve and response in in vitro fertilization by La Marca, Antonio, M.D., Ph.D, Sighinolfi, Giovanna, M.D, Argento, Cindy, M.D, Grisendi, Valentina, M.D, Casarini, Livio, M.D, Volpe, Annibale, M.D, Simoni, Manuela, M.D

“…Since gonadotropins are the fundamental hormones that control ovarian activity, genetic polymorphisms may alter gonadal responsiveness to glycoproteins; hence…”
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Editorial: Follicle-Stimulating Hormone: Fertility and Beyond by Simoni, Manuela, Huhtaniemi, Ilpo, Santi, Daniele, Casarini, Livio

“…Follicle-Stimulating Hormone: Fertility and Beyond Propagating life to the next generation is a hormone-dependent process relying on the individual wish to…”
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