Search Results - "Casanova, Magali"

Cell death in Leishmania by Basmaciyan, Louise, Casanova, Magali

“…Leishmaniases still represent a global scourge and new therapeutic tools are necessary to replace the current expensive, difficult to administer treatments…”
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Calcein+/PI- as an early apoptotic feature in Leishmania by Basmaciyan, Louise, Azas, Nadine, Casanova, Magali

“…Although leishmaniases are responsible for high morbidity and mortality all over the world, no really satisfying treatment exists. Furthermore, the…”
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A potential acetyltransferase involved in Leishmania major metacaspase-dependent cell death by Basmaciyan, Louise, Azas, Nadine, Casanova, Magali

“…Currently, there is no satisfactory treatment for leishmaniases, owing to the cost, mode of administration, side effects and to the increasing emergence of…”
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Promising antibacterial efficacy of arenicin peptides against the emerging opportunistic pathogen Mycobacterium abscessus by Casanova, Magali, Maresca, Marc, Poncin, Isabelle, Point, Vanessa, Olleik, Hamza, Boidin-Wichlacz, Céline, Tasiemski, Aurélie, Mabrouk, Kamel, Cavalier, Jean-François, Canaan, Stéphane

“…Mycobacterium abscessus, a fast-growing non-tuberculous mycobacterium, is an emerging opportunistic pathogen responsible for chronic bronchopulmonary…”
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(De)glutamylation and cell death in Leishmania parasites by Basmaciyan, Louise, Robinson, Derrick R, Azas, Nadine, Casanova, Magali

“…Trypanosomatids are flagellated protozoan parasites that are very unusual in terms of cytoskeleton organization but also in terms of cell death. Most of the…”
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Temporal analysis of the autophagic and apoptotic phenotypes in Leishmania parasites by Basmaciyan, Louise, Berry, Laurence, Gros, Julie, Azas, Nadine, Casanova, Magali

“…The leishmaniases are worldwide neglected tropical diseases caused by parasitic protozoa of the genus. Different stimuli induce cell death, but the proteins…”
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A novel hydrolase with a pro-death activity from the protozoan parasite Leishmania major by Basmaciyan, Louise, Jacquet, Pauline, Azas, Nadine, Casanova, Magali

“…Apoptosis is a cell death process generally described as involving a cascade of caspase activation, death receptors and/or pro- and antiapoptotic molecules…”
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Design and Synthesis of Novel Amino and Acetamidoaurones with Antimicrobial Activities by Di Maio, Attilio, Olleik, Hamza, Courvoisier-Dezord, Elise, Guillier, Sophie, Neulat-Ripoll, Fabienne, Haudecoeur, Romain, Bolla, Jean-Michel, Casanova, Magali, Cavalier, Jean-François, Canaan, Stéphane, Pique, Valérie, Charmasson, Yolande, Baydoun, Elias, Hijazi, Akram, Perrier, Josette, Maresca, Marc, Robin, Maxime

“…The development of new and effective antimicrobial compounds is urgent due to the emergence of resistant bacteria. Natural plant flavonoids are known to be…”
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Evaluation of the Efficiency of Random and Diblock Methacrylate-Based Amphiphilic Cationic Polymers against Major Bacterial Pathogens Associated with Cystic Fibrosis by Casanova, Magali, Olleik, Hamza, Hdiouech, Slim, Roblin, Clarisse, Cavalier, Jean-François, Point, Vanessa, Jeannot, Katy, Caron, Baptiste, Perrier, Josette, Charriau, Siméon, Lafond, Mickael, Guillaneuf, Yohann, Canaan, Stéphane, Lefay, Catherine, Maresca, Marc

“…Cystic fibrosis (CF) is associated with repeated lung bacterial infection, mainly by , , and , all known to be or becoming resistant to several antibiotics,…”
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Different apoptosis pathways in Leishmania parasites by Basmaciyan, Louise, Azas, Nadine, Casanova, Magali

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Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases by Minina, Elena A., Staal, Jens, Alvarez, Vanina E., Berges, John A., Berman-Frank, Ilana, Beyaert, Rudi, Bidle, Kay D., Bornancin, Frédéric, Casanova, Magali, Cazzulo, Juan J., Choi, Chang Jae, Coll, Nuria S., Dixit, Vishva M., Dolinar, Marko, Fasel, Nicolas, Funk, Christiane, Gallois, Patrick, Gevaert, Kris, Gutierrez-Beltran, Emilio, Hailfinger, Stephan, Klemenčič, Marina, Koonin, Eugene V., Krappmann, Daniel, Linusson, Anna, Machado, Maurício F.M., Madeo, Frank, Megeney, Lynn A., Moschou, Panagiotis N., Mottram, Jeremy C., Nyström, Thomas, Osiewacz, Heinz D., Overall, Christopher M., Pandey, Kailash C., Ruland, Jürgen, Salvesen, Guy S., Shi, Yigong, Smertenko, Andrei, Stael, Simon, Ståhlberg, Jerry, Suárez, María Fernanda, Thome, Margot, Tuominen, Hannele, Van Breusegem, Frank, van der Hoorn, Renier A.L., Vardi, Assaf, Zhivotovsky, Boris, Lam, Eric, Bozhkov, Peter V.

“…Metacaspases and paracaspases are proteases that were first identified as containing a caspase-like structural fold ( Uren et al., 2000 ). Like caspases, meta-…”
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Characterisation of polyglutamylases in trypanosomatids by Casanova, Magali, de Monbrison, Frédérique, van Dijk, Juliette, Janke, Carsten, Pagès, Michel, Bastien, Patrick

“…[Display omitted] •Microtubules are highly polyglutamylated in Leishmania major and Trypanosoma brucei.•Seven Tubulin Tyrosine Ligase-Like (TTLL)…”
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Discovery of a new antileishmanial hit in 8-nitroquinoline series by Paloque, Lucie, Verhaeghe, Pierre, Casanova, Magali, Castera-Ducros, Caroline, Dumètre, Aurélien, Mbatchi, Litaty, Hutter, Sébastien, Kraiem-M'Rabet, Manel, Laget, Michèle, Remusat, Vincent, Rault, Sylvain, Rathelot, Pascal, Azas, Nadine, Vanelle, Patrice

“…A series of nitrated 2-substituted-quinolines was synthesized and evaluated in vitro toward Leishmania donovani promastigotes. In parallel, the in vitro…”
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A new, rapid and sensitive bioluminescence assay for drug screening on Leishmania by Paloque, Lucie, Vidal, Nicolas, Casanova, Magali, Dumètre, Aurélien, Verhaeghe, Pierre, Parzy, Daniel, Azas, Nadine

“…We validated a new method, based on luciferine/luciferase bioluminescence, for drug screening on promastigotes of different Leishmania species. Results…”
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Microtubule-severing proteins are involved in flagellar length control and mitosis in Trypanosomatids by Casanova, Magali, Crobu, Lucien, Blaineau, Christine, Bourgeois, Nathalie, Bastien, Patrick, Pagès, Michel

“…Microtubules are key players in the biology of Trypanosomatid parasites, not only as classical components of the mitotic spindle, microtubule-organizing…”
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Nongenotoxic 3‑Nitroimidazo[1,2‑a]pyridines Are NTR1 Substrates That Display Potent in Vitro Antileishmanial Activity by Fersing, Cyril, Basmaciyan, Louise, Boudot, Clotilde, Pedron, Julien, Hutter, Sébastien, Cohen, Anita, Castera-Ducros, Caroline, Primas, Nicolas, Laget, Michèle, Casanova, Magali, Bourgeade-Delmas, Sandra, Piednoel, Mélanie, Sournia-Saquet, Alix, Belle Mbou, Valère, Courtioux, Bertrand, Boutet-Robinet, Élisa, Since, Marc, Milne, Rachel, Wyllie, Susan, Fairlamb, Alan H, Valentin, Alexis, Rathelot, Pascal, Verhaeghe, Pierre, Vanelle, Patrice, Azas, Nadine

“…Twenty nine original 3-nitroimidazo­[1,2-a]­pyridine derivatives, bearing a phenylthio (or benzylthio) moiety at position 8 of the scaffold, were synthesized…”
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Targeting the human parasite Leishmania donovani: Discovery of a new promising anti-infectious pharmacophore in 3-nitroimidazo[1,2-a]pyridine series by Castera-Ducros, Caroline, Paloque, Lucie, Verhaeghe, Pierre, Casanova, Magali, Cantelli, Christophe, Hutter, Sébastien, Tanguy, Floriane, Laget, Michèle, Remusat, Vincent, Cohen, Anita, Crozet, Maxime D., Rathelot, Pascal, Azas, Nadine, Vanelle, Patrice

“…We report herein the discovery of antileishmanial molecules based on the imidazo[1,2-a]pyridine ring. In vitro screenings of imidazopyridines belonging to our…”
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Implication of different domains of the Leishmania major metacaspase in cell death and autophagy by Casanova, M, Gonzalez, I J, Sprissler, C, Zalila, H, Dacher, M, Basmaciyan, L, Späth, G F, Azas, N, Fasel, N

“…Metacaspases (MCAs) are cysteine peptidases expressed in plants, fungi and protozoa, with a caspase-like histidine–cysteine catalytic dyad, but differing from…”
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Inhibition of active nuclear transport is an intrinsic trigger of programmed cell death in trypanosomatids by Casanova, M, Portalès, P, Blaineau, C, Crobu, L, Bastien, P, Pagès, M

“…The link between nucleocytoplasmic transport and apoptosis remains controversial. Nucleocytoplasmic exchange of molecules seems indeed essential for the…”
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