Search Results - "Casanova, Francesco"

Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study by Karageorgiou, Vasilios, Casanova, Francesco, O'Loughlin, Jessica, Green, Harry, McKinley, Trevelyan J, Bowden, Jack, Tyrrell, Jessica

“…Abstract Background Major depressive disorder (MDD) has a significant impact on global burden of disease. Complications in clinical management can occur when…”
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Higher adiposity and mental health: causal inference using Mendelian randomization by Casanova, Francesco, O’Loughlin, Jessica, Martin, Susan, Beaumont, Robin N, Wood, Andrew R, Watkins, Edward R, Freathy, Rachel M, Hagenaars, Saskia P, Frayling, Timothy M, Yaghootkar, Hanieh, Tyrrell, Jess

“…Abstract Higher adiposity is an established risk factor for psychiatric diseases including depression and anxiety. The associations between adiposity and…”
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Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study by Casanova, Francesco, O'Loughlin, Jessica, Karageorgiou, Vasilis, Beaumont, Robin N, Bowden, Jack, Wood, Andrew R, Tyrrell, Jessica

“…Mental health conditions represent one of the major groups of non-transmissible diseases. Physical activity (PA) and sedentary time (ST) have been shown to…”
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MRI-derived brain iron, grey matter volume, and risk of dementia and Parkinson's disease: Observational and genetic analysis in the UK Biobank cohort by Casanova, Francesco, Tian, Qu, Williamson, Daniel S., Qian, Yong, Zweibaum, David, Ding, Jun, Atkins, Janice L., Melzer, David, Ferrucci, Luigi, Pilling, Luke C.

“…Iron overload is observed in neurodegenerative diseases, especially Alzheimer's disease (AD) and Parkinson's disease (PD). Homozygotes for the iron-overload…”
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The impact of major depressive disorder on glycaemic control in type 2 diabetes: a longitudinal cohort study using UK Biobank primary care records by Gillett, Alexandra C, Hagenaars, Saskia P, Handley, Dale, Casanova, Francesco, Young, Katherine G, Green, Harry, Lewis, Cathryn M, Tyrrell, Jess

“…This study evaluates longitudinal associations between glycaemic control, measured by mean and within-patient variability of glycated haemaglobin (HbA1c)…”
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The genetics of falling susceptibility and identification of causal risk factors by Smith, Matt C., O’Loughlin, Jessica, Karageorgiou, Vasileios, Casanova, Francesco, Williams, Genevieve K. R., Hilton, Malcolm, Tyrrell, Jessica

“…Falls represent a huge health and economic burden. Whilst many factors are associated with fall risk (e.g. obesity and physical inactivity) there is limited…”
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A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure by Frayling, Timothy M., Beaumont, Robin N., Jones, Samuel E., Yaghootkar, Hanieh, Tuke, Marcus A., Ruth, Katherine S., Casanova, Francesco, West, Ben, Locke, Jonathan, Sharp, Seth, Ji, Yingjie, Thompson, William, Harrison, Jamie, Etheridge, Amy S., Gallins, Paul J., Jima, Dereje, Wright, Fred, Zhou, Yihui, Innocenti, Federico, Lindgren, Cecilia M., Grarup, Niels, Murray, Anna, Freathy, Rachel M., Weedon, Michael N., Tyrrell, Jessica, Wood, Andrew R.

“…Fibroblast growth factor 21 (FGF21) is a hormone that has insulin-sensitizing properties. Some trials of FGF21 analogs show weight loss and lipid-lowering…”
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Mendelian randomisation study of body composition and depression in people of East Asian ancestry highlights potential setting-specific causality by O'Loughlin, Jessica, Casanova, Francesco, Fairhurst-Hunter, Zammy, Hughes, Amanda, Bowden, Jack, Watkins, Edward R, Freathy, Rachel M, Millwood, Iona Y, Lin, Kuang, Chen, Zhengming, Li, Liming, Lv, Jun, Walters, Robin G, Howe, Laura D, Kuchenbaecker, Karoline, Tyrrell, Jessica

“…Extensive evidence links higher body mass index (BMI) to higher odds of depression in people of European ancestry. However, our understanding of the…”
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In vivo Measurement of Intraosseous Vascular Haemodynamic Markers in Human Bone Tissue Utilising Near Infrared Spectroscopy by Meertens, Robert, Knapp, Karen M., Strain, William David, Casanova, Francesco, Ball, Susan, Fulford, Jon, Thorn, Clare

“…Objective: Poor vascular health is associated with reduced bone strength and increased risk of fragility fracture. However, direct measurement of intraosseous…”
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BMI and well-being in people of East Asian and European ancestry: a Mendelian randomisation study by O’Loughlin, Jessica, Casanova, Francesco, Hughes, Amanda, Fairhurst-Hunter, Zammy, Li, Liming, Chen, Zhengming, Bowden, Jack, Watkins, Ed, Freathy, Rachel M., Howe, Laura D., Walters, Robin G., Tyrrell, Jessica

“…Previous studies have linked higher body mass index (BMI) to lower subjective well-being in adult European ancestry populations. However, our understanding of…”
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Reservoir‐excess pressure parameters are independently associated with NT‐proBNP in older adults by Aizawa, Kunihiko, Hughes, Alun D., Casanova, Francesco, Gooding, Kim M., Gates, Phillip E., Mawson, David M., Williams, Jennifer, Goncalves, Isabel, Nilsson, Jan, Khan, Faisel, Colhoun, Helen M., Palombo, Carlo, Parker, Kim H., Shore, Angela C.

“…Aims Parameters derived from reservoir‐excess pressure analysis have been demonstrated to predict cardiovascular events. Thus, altered reservoir‐excess…”
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P17 Comparisons of Carotid-femoral Pulse Wave Velocity Obtained from the Surface-distance Measurement and from the Population-derived Distance Formula: Associations with Macro- and Microvascular Alterations in Older Adults by Aizawa, Kunihiko, Casanova, Francesco, Mawson, Dave, Gooding, Kim, Elyas, Salim, Adingupu, Damilola, Strain, David, Gates, Phillip, Shore, Angela

“…Introduction Inaccurate determination of arterial path-length by surface-distance (SD) measurement is an inherent source of error in calculating…”
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P74: Wall Shear Rate and Brachial Artery Flow-Mediated Dilatory Response Between Healthy Young and Older Populations Using Multi-Gate Spectral Doppler Ultrasound by Aizawa, Kunihiko, Sbragi, Sara, Ramalli, Alessandro, Tortoli, Piero, Casanova, Francesco, Morizzo, Carmela, Thorn, Clare, Shore, Angela, Gates, Phillip, Palombo, Carlo

“…Background Ageing is associated with an impaired brachial artery flow-mediated dilatation (FMD) response and a reduced wall shear rate (WSR) stimulus may…”
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P19: Influence of Brachial Artery Stiffness on Flow-Mediated Dilatation in Healthy Young and Older Populations by Aizawa, Kunihiko, Sbragi, Sara, Ramalli, Alessandro, Tortoli, Piero, Casanova, Francesco, Morizzo, Carmela, Thorn, Clare, Shore, Angela, Gates, Phillip, Palombo, Carlo

“…Background Increased brachial artery (BA) stiffness has previously been shown to affect the magnitude of FMD response in patients with high cardiovascular…”
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Fermentative activity of promising yeasts for cereal-based beverages using CO2 headspace analysis by CASANOVA, Francesco Pio, BEVILACQUA, Antonio, PETRUZZI, Leonardo, SINIGAGLIA, Milena, CORBO, Maria Rosaria

“…This article proposes an approach based on the evaluation of CO2 produced by Saccharomyces cerevisiae var. boulardii, Kluyveromyces lactis × Saccharomyces…”
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3.2 Reservoir Pressure Integral is Independently Associated with the Reduction in Renal Function in an Older Population by Aizawa, Kunihiko, Casanova, Francesco, Mawson, David M., Gooding, Kim M., Strain, W. David, Gates, Phillip E., Östling, Gerd, Khan, Faisel, Colhoun, Helen M., Palombo, Carlo, Parker, Kim H., Nilsson, Jan, Shore, Angela C., Hughes, Alun D.

“…Background Central haemodynamic parameters derived from reservoir pressure analysis (RPA-parameters) exhibit prognostic utility. Alterations in reservoir…”
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A Simple Step Test to Estimate Cardio-Respiratory Fitness Levels of Rheumatoid Arthritis Patients in a Clinical Setting by Thom, Jeanette M., Casanova, Francesco, Lemmey, Andrew B., Maddison, Peter J., Jones, Jeremy G., Ahmad, Yasmeen A., Cooney, Jennifer K., Moore, Jonathan P.

“…Purpose. Exercise tests represent an important clinical tool to evaluate cardio-respiratory fitness and to predict future adverse cardiovascular events…”
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8.10 BRACHIAL ARTERY FLOW-MEDIATED DILATATION: DIFFERENT PATTERNS OF WALL SHEAR RATE INCREASE DURING REACTIVE HYPERAEMIA by Aizawa, Kunihiko, Sbragi, Sara, Ramalli, Alessandro, Tortoli, Piero, Casanova, Francesco, Morizzo, Carmela, Thorn, Clare, Shore, Angela, Gates, Phillip, Palombo, Carlo

“…Background: Wall shear rate (WSR) is considered an important stimulus for flow-mediated dilatation (FMD). However, its estimation by conventional ultrasound is…”
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P3.5 Type 2 Diabetes Exacerbates Carotid Artery Echogenicity and Central Artery Stiffness in Middle-Aged and Older Individuals by Aizawa, Kunihiko, Casanova, Francesco, Mawson, Dave, Elyas, Salim, Adingupu, Damilola, Gooding, Kim, Strain, David, Shore, Angela, Gates, Phillip

“…Grey scale median of the common carotid artery intima-media complex (IM-GSM) characterizes the composition of the arterial wall and low IM-GSM reflects more…”
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Functional Beverages: The Emerging Side of Functional Foods: Commercial Trends, Research, and Health Implications by Corbo, Maria Rosaria, Bevilacqua, Antonio, Petruzzi, Leonardo, Casanova, Francesco Pio, Sinigaglia, Milena

“…Abstract In recent times, there has been growing recognition of the key role of foods and beverages in disease prevention and treatment. Thus, the production…”
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