Search Results - "Casanova, E"

Regulation of Arf Activation: the Sec7 Family of Guanine Nucleotide Exchange Factors by Casanova, James E

“…The ADP ribosylation factors (Arfs) are a family of small, ubiquitously expressed and evolutionarily conserved guanosine triphosphatases that are key…”
Get full text

Activation of focal adhesion kinase by Salmonella suppresses autophagy via an Akt/mTOR signaling pathway and promotes bacterial survival in macrophages by Owen, Katherine A, Meyer, Corey B, Bouton, Amy H, Casanova, James E

“…Autophagy has emerged as an important antimicrobial host defense mechanism that not only orchestrates the systemic immune response, but also functions in a…”
Get full text

Regulation of actin cytoskeleton dynamics by Arf-family GTPases by Myers, Kenneth R, Casanova, James E

“…Small GTPases of the Arf family are best known for their role in vesicular transport, wherein they nucleate the assembly of coat proteins at sites of carrier…”
Get full text

Design recommendations for patch loading resistance of longitudinally stiffened I-girders by Loaiza, N., Graciano, C., Casanova, E.

“…•The behavior of longitudinally stiffened webs subject to patch loading is studied.•The influence on patch loading resistance of a stiffener placed at…”
Get full text

TFEB inhibition induces melanoma shut-down by blocking the cell cycle and rewiring metabolism by Ariano, C., Costanza, F., Akman, M., Riganti, C., Corà, D., Casanova, E., Astanina, E., Comunanza, V., Bussolino, F., Doronzo, G.

“…Melanomas are characterised by accelerated cell proliferation and metabolic reprogramming resulting from the contemporary dysregulation of the MAPK pathway,…”
Get full text

Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex by D'Souza, Ryan S, Lim, Jun Y, Turgut, Alper, Servage, Kelly, Zhang, Junmei, Orth, Kim, Sosale, Nisha G, Lazzara, Matthew J, Allegood, Jeremy, Casanova, James E

“…Coordinated assembly and disassembly of integrin-mediated focal adhesions (FAs) is essential for cell migration. Many studies have shown that FA disassembly…”
Get full text

Identification of natural red and purple dyes on textiles by Fiber-optics Reflectance Spectroscopy by Maynez-Rojas, M.A., Casanova-González, E., Ruvalcaba-Sil, J.L.

“…Understanding dye chemistry and dye processes is an important issue for studies of cultural heritage collections and science conservation. Fiber Optics…”
Get full text

Chronic consumption of dietary proanthocyanidins modulates peripheral clocks in healthy and obese rats by Ribas-Latre, A., Baselga-Escudero, L., Casanova, E., Arola-Arnal, A., Salvadó, M.J., Arola, L., Bladé, C.

“…Circadian rhythm plays an important role in maintaining homeostasis, and its disruption increases the risk of developing metabolic syndrome. Circadian rhythm…”
Get full text

Arf6-GEF BRAG1 regulates JNK-mediated synaptic removal of GluA1-containing AMPA receptors: a new mechanism for nonsyndromic X-linked mental disorder by Myers, Kenneth R, Wang, Guangfu, Sheng, Yanghui, Conger, Kathryn K, Casanova, James E, Zhu, J Julius

“…Activity-dependent modifications of excitatory synapses contribute to synaptic maturation and plasticity, and are critical for learning and memory…”
Get full text

The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria by Billings, Emily A, Lee, Chang Sup, Owen, Katherine A, D'Souza, Ryan S, Ravichandran, Kodi S, Casanova, James E

“…The detection of microbes and initiation of an innate immune response occur through pattern recognition receptors (PRRs), which are critical for the production…”
Get more information

Activation of ARF6 by ARNO Stimulates Epithelial Cell Migration through Downstream Activation of Both Rac1 and Phospholipase D by Santy, Lorraine C., Casanova, James E.

“…Migration of epithelial cells is essential for tissue morphogenesis, wound healing, and metastasis of epithelial tumors. Here we show that ARNO, a guanine…”
Get full text

Agonist antibodies activating the Met receptor protect cardiomyoblasts from cobalt chloride-induced apoptosis and autophagy by Gallo, S, Gatti, S, Sala, V, Albano, R, Costelli, P, Casanova, E, Comoglio, P M, Crepaldi, T

“…Met, the tyrosine kinase receptor for hepatocyte growth factor (HGF), mainly activates prosurvival pathways, including protection from apoptosis. In this work,…”
Get full text

Brain angiogenesis inhibitor 1 (BAI1) is a pattern recognition receptor that mediates macrophage binding and engulfment of Gram-negative bacteria by Das, Soumita, Owen, Katherine A, Ly, Kim T, Park, Daeho, Black, Steven G, Wilson, Jeffrey M, Sifri, Costi D, Ravichandran, Kodi S, Ernst, Peter B, Casanova, James E

“…Bacterial recognition by host cells is essential for initiation of infection and the host response. Bacteria interact with host cells via multiple pattern…”
Get full text

Targeting hedgehog signaling reduces self-renewal in embryonal rhabdomyosarcoma by Satheesha, S, Manzella, G, Bovay, A, Casanova, E A, Bode, P K, Belle, R, Feuchtgruber, S, Jaaks, P, Dogan, N, Koscielniak, E, Schäfer, B W

“…Current treatment regimens for rhabdomyosarcoma (RMS), the most common pediatric soft tissue cancer, rely on conventional chemotherapy, and although they show…”
Get full text

Multi-center study on overall clinical complexity of patients with prolonged disorders of consciousness of different etiologies by Estraneo, A, Masotta, O, Bartolo, M, Pistoia, F, Perin, C, Marino, S, Lucca, L, Pingue, V, Casanova, E, Romoli, A, Gentile, S, Formisano, R, Salvi, GP, Scarponi, F, De Tanti, A, Bongioanni, P, Rossato, E, Santangelo, A, Diana, AR, Gambarin, M, Intiso, D, Antenucci, R, Premoselli, S, Bertoni, M, De Bellis, F

“…Aim: to assess overall clinical complexity of patients with acquired disorders of consciousness (DoC) in vegetative state/unresponsive wakefulness syndrome…”
Get full text

Rab4 Orchestrates a Small GTPase Cascade for Recruitment of Adaptor Proteins to Early Endosomes by D’Souza, Ryan S., Semus, Rachel, Billings, Emily A., Meyer, Corey B., Conger, Kathryn, Casanova, James E.

“…Early, sorting endosomes are a major crossroad of membrane traffic, at the intersection of the endocytic and exocytic pathways. The sorting of endosomal cargo…”
Get full text

Estimation and visualization of sagittal kinematics of lower limbs orientation using body-fixed sensors by Dejnabadi, H., Jolles, B.M., Casanova, E., Fua, P., Aminian, K.

“…A new method of estimating lower limbs orientations using a combination of accelerometers and gyroscopes is presented. The model is based on estimating the…”
Get full text

Turning on ARF: the Sec7 family of guanine-nucleotide-exchange factors by Jackson, Catherine L., Casanova, James E.

“…ARF proteins are important regulators of membrane dynamics and protein transport within the eukaryotic cell. The Sec7 domain is ∼200 amino acids in size and…”
Get full text

The Effects of Providing Outdoor Access to Broilers in the Tropics on Their Behaviour and Stress Responses by Sánchez-Casanova, Rubí E., Sarmiento-Franco, Luis, Phillips, Clive J. C.

“…The effects of outdoor access, stocking density, and age on broiler behavior, stress, and health indicators in a tropical climate were assessed over two…”
Get full text

Salmonella Manipulates Autophagy to “Serve and Protect” by Owen, Katherine A., Casanova, James E.

“…Many intracellular pathogens, including Salmonella typhimurium, trigger autophagy in host cells, which is widely thought to restrict intracellular growth and…”
Get full text