Search Results - "Casamayor, Isabel"

First-in-human, Pharmacokinetic and Pharmacodynamic Phase I Study of Resminostat, an Oral Histone Deacetylase Inhibitor, in Patients with Advanced Solid Tumors by BRUNETTO, André T, JOO ERN ANG, HAUNS, Bernhard, STROBEL, Vera, HENTSCH, Bernd, DE BONO, Johann S, LAI, Rohit, OLMOS, David, MOLIFE, L. Rhoda, KRISTELEIT, Rebecca, PARKER, Ann, CASAMAYOR, Isabel, OLALEYE, Muyibat, MAIS, Anna

“…This first-in-human dose-escalating trial investigated the safety, tolerability, maximum tolerated dose (MTD), dose-limiting toxicities (DLT),…”
Get full text

Quantification of periciliary fluid height in human airway biopsies is feasible, but not suitable as a biomarker by Griesenbach, Uta, Soussi, Samia, Larsen, Mia B, Casamayor, Isabel, Dewar, Ann, Regamey, Nicolas, Bush, Andrew, Shah, Pallav L, Davies, Jane C, Alton, Eric W F W

“…The "low volume hypothesis," stating that imbalanced ion movement across the cystic fibrosis (CF) airway epithelium leads to a reduction in periciliary fluid…”
Get full text

Limitations of the murine nose in the development of nonviral airway gene transfer by Griesenbach, Uta, Sumner-Jones, Stephanie G, Holder, Emma, Munkonge, Felix M, Wodehouse, Theresa, Smith, Stephen N, Wasowicz, Marguerite Y, Pringle, Ian, Casamayor, Isabel, Chan, Mario, Coles, Rebecca, Cornish, Nikki, Dewar, Ann, Doherty, Ann, Farley, Raymond, Green, Anne-Marie, Jones, Bryony L, Larsen, Mia D B, Lawton, Anna E, Manvell, Michelle, Painter, Hazel, Singh, Charanjit, Somerton, Lucinda, Stevenson, Barbara, Varathalingam, Anusha, Siegel, Craig, Scheule, Ronald K, Cheng, Seng H, Davies, Jane C, Porteous, David J, Gill, Deborah R, Boyd, A Christopher, Hyde, Steve C, Alton, Eric W F W

“…A clinical program to assess whether lipid GL67A-mediated gene transfer can ameliorate cystic fibrosis (CF) lung disease is currently being undertaken by the…”
Get full text