Search Results - "Casaletto, Kaitlin B"
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Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain
Published in Science (American Association for the Advancement of Science) (10-07-2020)“…Reversing brain aging may be possible through systemic interventions such as exercise. We found that administration of circulating blood factors in plasma from…”
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Demographically Corrected Normative Standards for the English Version of the NIH Toolbox Cognition Battery
Published in Journal of the International Neuropsychological Society (01-05-2015)“…Demographic factors impact neuropsychological test performances and accounting for them may help to better elucidate current brain functioning. The NIH Toolbox…”
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Reliability and validity of composite scores from the NIH Toolbox Cognition Battery in adults
Published in Journal of the International Neuropsychological Society (01-07-2014)“…This study describes psychometric properties of the NIH Toolbox Cognition Battery (NIHTB-CB) Composite Scores in an adult sample. The NIHTB-CB was designed for…”
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Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer's disease
Published in Alzheimer's & dementia (01-04-2020)“…We investigated plasma proteomic markers of astrocytopathy, brain degeneration, plasticity, and inflammation in sporadic early-onset versus late-onset…”
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Cerebrospinal Fluid and Plasma Levels of Inflammation Differentially Relate to CNS Markers of Alzheimer's Disease Pathology and Neuronal Damage
Published in Journal of Alzheimer's disease (01-01-2018)“…Inflammatory markers have been shown to predict neurocognitive outcomes in aging adults; however, the degree to which peripheral markers mirror the central…”
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Data-driven physical actigraphy patterns relate to cognitive and vascular health in older adults
Published in Experimental gerontology (01-07-2023)“…Health benefits of physical activity (PA) are well known; however, specific PA patterns that relate most strongly to cognitive aging outcomes are poorly…”
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Increases in a Pro-inflammatory Chemokine, MCP-1, Are Related to Decreases in Memory Over Time
Published in Frontiers in aging neuroscience (13-02-2019)“…: To determine the longitudinal relationship between monocyte chemotactic protein 1 (MCP-1)/CCL2 and memory function in older adults. : We examined…”
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Multimodal lifestyle engagement patterns support cognitive stability beyond neuropathological burden
Published in Alzheimer's research & therapy (18-12-2023)“…Modifiable lifestyle behaviors account for a large proportion of dementia risk. However, the combined contributions of multidomain lifestyle patterns to…”
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Retinal thinning is uniquely associated with medial temporal lobe atrophy in neurologically normal older adults
Published in Neurobiology of aging (01-03-2017)“…Abstract Given the converging pathological and epidemiological data indicating a relationship between retinal integrity and neurodegeneration, including…”
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AD and non‐AD mediators of the pathway between the APOE genotype and cognition
Published in Alzheimer's & dementia (01-06-2023)“…Introduction The apolipoprotein E (APOE) genotype is a driver of cognitive decline and dementia. We used causal mediation methods to characterize pathways…”
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Get Moving! Increases in Physical Activity Are Associated With Increasing Functional Connectivity Trajectories in Typically Aging Adults
Published in Frontiers in aging neuroscience (28-04-2020)“…: Physical activity closely relates to cognition and brain structure as we age. However, the neural mechanisms underlying this relationship in humans remain…”
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Physical activity measurement in older adults: Wearables versus self-report
Published in Frontiers in digital health (31-08-2022)“…Physical activity (PA) is associated with preserved age-related body and brain health. However, PA quantification can vary. Commercial-grade wearable monitors…”
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Wearable Use in an Observational Study Among Older Adults: Adherence, Feasibility, and Effects of Clinicodemographic Factors
Published in Frontiers in digital health (10-06-2022)“…Wearables have great potential to improve monitoring and delivery of physical activity interventions to older adults with downstream benefits to multisystem…”
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Clinical implications of head trauma in frontotemporal dementia and primary progressive aphasia
Published in Alzheimer's research & therapy (29-08-2024)“…Traumatic brain injury (TBI) and repetitive head impacts (RHI) have been linked to increased risk for multiple types of neurodegenerative disease, higher…”
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Mild Motor Signs Matter in Typical Brain Aging: The Value of the UPDRS Score Within a Functionally Intact Cohort of Older Adults
Published in Frontiers in aging neuroscience (11-02-2021)“…To characterize the clinical correlates of subclinical Parkinsonian signs, including longitudinal cognitive and neural (via functional connectivity) outcomes,…”
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Alzheimer's pathology is associated with altered cognition, brain volume, and plasma biomarker patterns in traumatic encephalopathy syndrome
Published in Alzheimer's research & therapy (21-07-2023)“…Traumatic encephalopathy syndrome (TES) is a clinical phenotype sensitive but non-specific to underlying chronic traumatic encephalopathy (CTE) neuropathology…”
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Neuropsychological Assessment: Past and Future
Published in Journal of the International Neuropsychological Society (01-10-2017)“…Neuropsychological assessment tools are the staple of our field. The development of standardized metrics sensitive to brain-behavior relationships has shaped…”
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Endophenotypic correlates of cognitive function in reproductive-age individuals with polycystic ovary syndrome
Published in F&S Reports (Online) (01-12-2022)“…To characterize cognitive performance in relation to hormonal and metabolic factors in women with polycystic ovary syndrome (PCOS). Cross-sectional study…”
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"Liquid Biopsy" of White Matter Hyperintensity in Functionally Normal Elders
Published in Frontiers in aging neuroscience (09-11-2018)“…In the aging brain, increased blood-brain barrier (BBB) leakage and white matter hyperintensity (WMH) on MRI are frequently presumed secondary to cerebral…”
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