Search Results - "Casale, Cesar H"

Tubulin Regulates Plasma Membrane Ca2+-ATPase Activity in a Lipid Environment-dependent Manner by Monesterolo, Noelia E., Santander, Verónica S., Campetelli, Alexis N., Rivelli Antonelli, Juan F., Nigra, Ayelén D., Balach, Melisa M., Muhlberger, Tamara, Previtali, Gabriela, Casale, César H.

“…Ca 2+ plays a crucial role in cell signaling, cytosolic Ca 2+ can change up to 10,000-fold in concentration due to the action of Ca 2+ -ATPases, including…”
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Regulation of aldose reductase activity by tubulin and phenolic acid derivates by Rivelli, Juan F., Ochoa, Ana L., Santander, Verónica S., Nigra, Ayelen, Previtali, Gabriela, Casale, César H.

“…In this work we demonstrate that aldose reductase (AR) interacts directly with tubulin and, was subjected to microtubule formation conditions, enzymatic AR…”
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Tubulin–Na+ ,K +‐ATPase interaction: Involvement in enzymatic regulation and cellular function by Santander, Veronica S., Campetelli, Alexis N., Monesterolo, Noelia E., Rivelli, Juan F., Nigra, Ayelen D., Arce, Carlos A., Casale, César H.

“…A new function for tubulin was described by our laboratory: acetylated tubulin forms a complex with Na+,K +‐ATPase (NKA) and inhibits its activity. This…”
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Tubulin-mediated anatomical and functional changes caused by Ca2+ in human erythrocytes by Balach, Melisa M., Santander, Verónica S., Elisio, Elida Y., Rivelli, Juan F., Muhlberger, Tamara, Campetelli, Alexis N., Casale, Cesar H., Monesterolo, Noelia E.

“…In previous research, we observed that tubulin can be found in three fractions within erythrocytes, i.e., attached to the membrane, as a soluble fraction, or…”
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Alterations of hemorheological parameters and tubulin content in erythrocytes from diabetic subjects by Nigra, Ayelén D., Monesterolo, Noelia E., Rivelli, Juan F., Amaiden, Marina R., Campetelli, Alexis N., Casale, Cesar H., Santander, Verónica S.

“…[Display omitted] •High glucose promote in erythrocytes translocation of tubulin to the membrane.•Membrane tubulin regulates erythrocyte deformability and…”
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Prevention of tubulin/aldose reductase association delays the development of pathological complications in diabetic rats by Rivelli Antonelli, Juan F., Santander, Verónica S., Nigra, Ayelen D., Monesterolo, Noelia E., Previtali, Gabriela, Primo, Emilianao, Otero, Lisandro H., Casale, César H.

“…In recent studies, we found that compounds derived from phenolic acids (CAFs) prevent the formation of the tubulin/aldose reductase complex and, consequently,…”
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High glucose levels induce inhibition of Na,K-ATPase via stimulation of aldose reductase, formation of microtubules and formation of an acetylated tubulin/Na,K-ATPase complex by Rivelli, Juan F., Amaiden, Marina R., Monesterolo, Noelia E., Previtali, Gabriela, Santander, Verónica S., Fernandez, Adriana, Arce, Carlos A., Casale, Cesar H.

“…Our previous studies demonstrated that acetylated tubulin forms a complex with Na+,K+-ATPase and thereby inhibits its enzyme activity in cultured COS and CAD…”
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Tubulin pools in human erythrocytes: altered distribution in hypertensive patients affects Na⁺, K⁺-ATPase activity by Amaiden, Marina R, Santander, Verónica S, Monesterolo, Noelia E, Campetelli, Alexis N, Rivelli, Juan F, Previtali, Gabriela, Arce, Carlos A, Casale, César H

“…The presence of tubulin in human erythrocytes was demonstrated using five different antibodies. Tubulin was distributed among three operationally…”
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Tubulin must be acetylated in order to form a complex with membrane Na⁺,K⁺-ATPase and to inhibit its enzyme activity by Santander, Verónica S, Bisig, C. Gastón, Purro, Silvia A, Casale, César H, Arce, Carlos A, Barra, Héctor S

“…In cells of neural and non-neural origin, tubulin forms a complex with plasma membrane Na⁺,K⁺-ATPase, resulting in inhibition of the enzyme activity. When…”
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Human erythrocytes: cytoskeleton and its origin by Nigra, Ayelén D., Casale, Cesar H., Santander, Verónica S.

“…In the last few years, erythrocytes have emerged as the main determinant of blood rheology. In mammals, these cells are devoid of nuclei and are, therefore,…”
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Erythrocyte plasma membrane potential: past and current methods for its measurement by Balach, Melisa M., Casale, Cesar H., Campetelli, Alexis N.

“…The plasma membrane functions both as a natural insulator and a diffusion barrier to the movement of ions. A wide variety of proteins transport and pump ions…”
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Tubulin is retained throughout the human hematopoietic/erythroid cell differentiation process and plays a structural role in sedimentable fraction of mature erythrocytes by Nigra, Ayelén D., Santander, Verónica S., Dircio-Maldonado, Roberto, Amaiden, Marina Rafaela, Monesterolo, Noelia E., Flores-Guzmán, Patricia, Muhlberger, Tamara, Rivelli, Juan F., Campetelli, Alexis N., Mayani, Héctor, Casale, Cesar H.

“…[Display omitted] •Tubulin in sedimentable fraction of erythrocytes (“Sed-tub”) is biochemically similar to tubulin in microtubules of precursor cells.•Sed-tub…”
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Effects of detyrosinated tubulin on Na+,K+-ATPase activity and erythrocyte function in hypertensive subjects by Amaiden, Marina R., Santander, Verónica S., Monesterolo, Noelia E., Nigra, Ayelen D., Rivelli, Juan F., Campetelli, Alexis N., Pie, Juan, Casale, Cesar H.

“…•Detyrosinated tubulin is able to inhibit the NKA activity.•Erythrocytes of hypertensive subjects have a reduced content and activity of TTL.•GluTub levels and…”
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Physical adsorption of aflatoxin B1 by lactic acid bacteria and Saccharomyces cerevisiae: a theoretical model by Bueno, Dante J, Casale, César H, Pizzolitto, Romina P, Salvano, Mario A, Oliver, Guillermo

“…The ability of lactic acid bacteria (LAB) and Saccharomyces cerevisiae to remove aflatoxin B1 (AFB1) from liquid medium was tested. The experimental results…”
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PMCA activity and membrane tubulin affect deformability of erythrocytes from normal and hypertensive human subjects by Monesterolo, Noelia E., Nigra, Ayelen D., Campetelli, Alexis N., Santander, Verónica S., Rivelli, Juan F., Arce, Carlos A., Casale, Cesar H.

“…Our previous studies demonstrated formation of a complex between acetylated tubulin and brain plasma membrane Ca2+-ATPase (PMCA), and the effect of the lipid…”
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Functional characterization of NIPBL physiological splice variants and eight splicing mutations in patients with Cornelia de Lange syndrome by Teresa-Rodrigo, María E, Eckhold, Juliane, Puisac, Beatriz, Dalski, Andreas, Gil-Rodríguez, María C, Braunholz, Diana, Baquero, Carolina, Hernández-Marcos, María, de Karam, Juan C, Ciero, Milagros, Santos-Simarro, Fernando, Lapunzina, Pablo, Wierzba, Jolanta, Casale, César H, Ramos, Feliciano J, Gillessen-Kaesbach, Gabriele, Kaiser, Frank J, Pié, Juan

“…Cornelia de Lange syndrome (CdLS) is a congenital developmental disorder characterized by distinctive craniofacial features, growth retardation, cognitive…”
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Involvement of membrane tubulin in erythrocyte deformability and blood pressure by Amaiden, Marina R, Monesterolo, Noelia E, Santander, Verónica S, Campetelli, Alexis N, Arce, Carlos A, Pie, Juan, Hope, Sandra I, Vatta, Marcelo S, Casale, Cesar H

“…OBJECTIVE:To test the hypothesis that erythrocyte deformability is influenced by changes in the content of membrane tubulin (Mem-tub). METHODS AND…”
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Submembraneous microtubule cytoskeleton: regulation of ATPases by interaction with acetylated tubulin by Arce, Carlos A., Casale, Cesar H., Barra, Héctor S.

“…The ATP‐hydrolysing enzymes (Na+,K+)‐, H+‐ and Ca2+‐ATPase are integral membrane proteins that play important roles in the exchange of ions and nutrients…”
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Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol by Arnedo, María, Menao, Sebastián, Puisac, Beatriz, Teresa-Rodrigo, María E., Gil-Rodríguez, María C., López-Viñas, Eduardo, Gómez-Puertas, Paulino, Casals, Nuria, Casale, César H., Hegardt, Fausto G., Pié, Juan

“…A novel lyase activity enzyme is characterized for the first time: HMG-CoA lyase-like1 (er-cHL), which is a close homolog of mitochondrial HMG-CoA lyase (mHL)…”
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Acetylated tubulin associates with the fifth cytoplasmic domain of Na(+)/K(+)-ATPase: possible anchorage site of microtubules to the plasma membrane by Zampar, Guillermo G, Chesta, María E, Carbajal, Agustín, Chanaday, Natalí L, Díaz, Nicolás M, Casale, César H, Arce, Carlos A

“…We showed previously that NKA (Na(+)/K(+)-ATPase) interacts with acetylated tubulin resulting in inhibition of its catalytic activity. In the present work we…”
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