Search Results - "Casalí, T."

Risk and protective factors for the appearance of first-episode psychosis: The role of childhood trauma and coping strategies by Vila-Badia, R., Serra-Arumí, C., Butjosa, A., Del Cacho, N., Abella, M., Colomer-Salvans, A., Cuevas-Esteban, J., Alcalde, R., Muñoz-Samons, D., Bogas, J.L., Usall, J., Abella, M, Alcalde, R, Álvarez, M, Bañuelos, M, Batllori, M, Bogas, JL, Bonilla, R, Butjosa, A, Camprodon, E, Casado, A, Casalí, T, Chavarria, Coromina, M, Cuautle, A, Cuevas- Esteban, J, Cunill, R, Cuñat, O, Del Cacho, N, del Hoyo, B, Diago, M, Dolz, M, Esteban-Sanjusto, M, Estrada, X, Iglésias-González, M, Jané, C, Jané Balsebre, Ò., López-Ortiz, C., Mansilla, M., Membrive, P., Meroño, S., Molano, A., Morelló, G., Muñoz-Samons, D., Nuñez, M., Ochoa, S., Pardo, M., Peláez, T, Pla, MM, Rodríguez, A, Rodríguez, MJ, Rodríguez Sáenz de Buruaga, L., Romans, C, Rubio-Abadal, E, Sánchez, L, Santos, A, Serra-Arumí, C, Sibelo, S, Teba, S, Tena, MC, Usall, J, Vallejo, G, Via, È, Vila-Badia, R, Vives, L.

Get full text

Microglia depletion rapidly and reversibly alters amyloid pathology by modification of plaque compaction and morphologies by Casali, Brad T., MacPherson, Kathryn P., Reed-Geaghan, Erin G., Landreth, Gary E.

“…Alzheimer's disease (AD) is a prominent neurodegenerative disorder characterized by deposition of β-amyloid (Aβ)-containing extracellular plaques, accompanied…”
Get full text

INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia by Tsai, Andy P., Lin, Peter Bor-Chian, Dong, Chuanpeng, Moutinho, Miguel, Casali, Brad T., Liu, Yunlong, Lamb, Bruce T., Landreth, Gary E., Oblak, Adrian L., Nho, Kwangsik

“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, robust microgliosis, neuroinflammation, and neuronal…”
Get full text

Omega-3 Fatty Acids Augment the Actions of Nuclear Receptor Agonists in a Mouse Model of Alzheimer's Disease by Casali, Brad T, Corona, Angela W, Mariani, Monica M, Karlo, J Colleen, Ghosal, Kaushik, Landreth, Gary E

“…Alzheimer's disease (AD) is a highly prevalent disorder for which there are no effective therapies. Accumulation of amyloid β (Aβ) peptides in the brain is…”
Get full text

The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease by Moutinho, Miguel, Puntambekar, Shweta S, Tsai, Andy P, Coronel, Israel, Lin, Peter B, Casali, Brad T, Martinez, Pablo, Oblak, Adrian L, Lasagna-Reeves, Cristian A, Lamb, Bruce T, Landreth, Gary E

“…Increased dietary intake of niacin has been correlated with reduced risk of Alzheimer's disease (AD). Niacin serves as a high-affinity ligand for the receptor…”
Get more information

The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease by Cheng-Hathaway, Paul J, Reed-Geaghan, Erin G, Jay, Taylor R, Casali, Brad T, Bemiller, Shane M, Puntambekar, Shweta S, von Saucken, Victoria E, Williams, Roxanne Y, Karlo, J Colleen, Moutinho, Miguel, Xu, Guixiang, Ransohoff, Richard M, Lamb, Bruce T, Landreth, Gary E

“…The R47H variant of Triggering Receptor Expressed on Myeloid cells 2 (TREM2) confers greatly increased risk for Alzheimer's disease (AD), reflective of a…”
Get full text

Microglial Function and Regulation during Development, Homeostasis and Alzheimer's Disease by Casali, Brad T, Reed-Geaghan, Erin G

“…Microglia are the resident immune cells of the brain, deriving from yolk sac progenitors that populate the brain parenchyma during development. During…”
Get full text

PLCG2 is associated with the inflammatory response and is induced by amyloid plaques in Alzheimer's disease by Tsai, Andy P, Dong, Chuanpeng, Lin, Peter Bor-Chian, Messenger, Evan J, Casali, Brad T, Moutinho, Miguel, Liu, Yunlong, Oblak, Adrian L, Lamb, Bruce T, Landreth, Gary E, Bissel, Stephanie J, Nho, Kwangsik

“…Alzheimer's disease (AD) is characterized by robust microgliosis and phenotypic changes that accompany disease pathogenesis. Accumulating evidence from genetic…”
Get full text

Therapeutic targeting of immunometabolism reveals a critical reliance on hexokinase 2 dosage for microglial activation and Alzheimer’s progression by Codocedo, Juan F., Mera-Reina, Claudia, Bor-Chian Lin, Peter, Fallen, Paul B., Puntambekar, Shweta S., Casali, Brad T., Jury-Garfe, Nur, Martinez, Pablo, Lasagna-Reeves, Cristian A., Landreth, Gary E.

“…Neuroinflammation is a prominent feature of Alzheimer’s disease (AD). Activated microglia undergo a reprogramming of cellular metabolism necessary to power…”
Get full text

Nuclear receptor agonist-driven modification of inflammation and amyloid pathology enhances and sustains cognitive improvements in a mouse model of Alzheimer's disease by Casali, Brad T, Reed-Geaghan, Erin G, Landreth, Gary E

“…Alzheimer's disease (AD) is a highly prevalent neurodegenerative disorder characterized by pathological hallmarks of beta-amyloid plaque deposits, tau…”
Get full text

ABCA1 is Necessary for Bexarotene-Mediated Clearance of Soluble Amyloid Beta from the Hippocampus of APP/PS1 Mice by Corona, Angela W., Kodoma, Nathan, Casali, Brad T., Landreth, Gary E.

“…Alzheimer’s disease (AD) is characterized by impaired clearance of amyloid beta (Aβ) peptides, leading to the accumulation of Aβ in the brain and subsequent…”
Get full text

Topical estradiol increases epidermal thickness and dermal collagen of foreskin prior to hypospadia surgery – Randomized double blinded controlled trial by Casali, T.G., Christina de Castro Paiva, K., Rodrigues, M.N., Santana Silva, C.E., Avarese de Figueiredo, A., de Bessa, J., Bastos, A.N., Marques Nogueira Castañon, M.C., Bastos Netto, J.M.

“…The use of preoperative topical testosterone stimulation prior to hypospadias correction aims to increase penile size and achieve better surgical results…”
Get full text

ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models by CRAMER, Paige E, CIRRITO, John R, BRUNDEN, Kurt R, WILSON, Donald A, LANDRETH, Gary E, WESSON, Daniel W, DANIEL LEE, C. Y, COLLEEN KARLO, J, ZINN, Adriana E, CASALI, Brad T, RESTIVO, Jessica L, GOEBET, Whitney D, JAMES, Michael J

“…Alzheimer's disease (AD) is associated with impaired clearance of β-amyloid (Aβ) from the brain, a process normally facilitated by apolipoprotein E (apoE)…”
Get full text

Combined Liver X Receptor/Peroxisome Proliferator-activated Receptor γ Agonist Treatment Reduces Amyloid β Levels and Improves Behavior in Amyloid Precursor Protein/Presenilin 1 Mice by Skerrett, Rebecca, Pellegrino, Mateus P., Casali, Brad T., Taraboanta, Laura, Landreth, Gary E.

“…Alzheimer disease (AD) is characterized by the extracellular accumulation of amyloid β (Aβ), which is accompanied by a robust inflammatory response in the…”
Get full text

Association of perceived social support with sociodemographic, clinical, and psychosocial variables in patients with first-episode psychosis by Serra-Arumí, Clara, Vila-Badia, Regina, Del Cacho, Núria, Butjosa, Anna, Abella, Manuel, Colomer-Salvans, Alícia, Cunill, Ruth, Tena, Mari Carmen, Véliz, Danae Ines, Bustos-Cardona, Tatiana, Dolz, Montse, PROFEP Group, Usall, Judith, Abella, M., Aguilar, S., Alba, L., Alcalde, R., Álvarez, M., Bañuelos, M., Batllori, M., Bogas, J.L., Bonilla, R., Bustos-Cardona, T., Butjosa, A., Camprodon, E., Casado-Ortega, A., Casalí, T., Chavarria, V., Colomer-Salvans, A., Coromina, M., Cuautle, A., Cuevas-Esteban, J., Cunill, R., Cuñat, O., Del Cacho, N., del Hoyo, B., Diago, M., Dolz, M., Esteban-Santjusto, M., Estrada, X., Fernández-Sanz, A., Iglesias-González, M., Jané, C., Jané, O., López-Ortiz, C., Mansilla, M., Membrive, P., Meroño, S., Molano, A., Morelló, G., Muñoz-Samons, D., Núñez, M., Ochoa, S., Pardo, M., Pelaez, T., Pla, M.M., Pou, C., Rodríguez, A., Rodríguez, M.J., Romans, C., Rubio-Abadal, E., Sáenz de Buruaga, L.R., Sánchez, L., Santos, A., Serra-Arumí, C., Sibelo, S., Teba, S., Tena, M.C., Usall, J., Vallejo, G., Véliz, D., Via, E., Vila-Badia, R., Vives, L.

“…Patients with first-episode psychosis (FEP) report deficits in social support (SS) and diminished and less satisfactory social networks than healthy controls…”
Get full text

The role of microglia niacin receptor (HCAR2) in Alzheimer's disease by Moutinho, Miguel, Tsai, Andy Po‐Yi, Puntambekar, Shweta S, Casali, Brad T, Lin, Peter Bor‐Chian, Patel, Jheel, Martínez, Pablo, Reeves, Cristian A Lasagna, Landreth, Gary E

“…Background Dietary intake of niacin reduces the risk of Alzheimer´s disease (AD) and protects against age‐related cognitive decline. Niacin is a ligand for the…”
Get full text

Aβ Extraction from Murine Brain Homogenates by Casali, Brad T, Landreth, Gary E

“…This protocol details beta-amyloid (Aβ) extraction from transgenic murine brain homogenates. Specifically, mechanical homogenization of brain tissue and…”
Get full text

Different effects of reducing agents on ω‐conotoxin GVIA inhibition of [3H]‐acetylcholine release from rat cortical slices and guinea‐pig myenteric plexus by Casali, T A A, Gomez, R S, Moraes‐Santos, T, Romano‐Silva, M A, Prado, M A M, Gomez, M V

“…The effect of reducing reagents on ω‐conotoxin GVIA (ω‐CgTX) inhibition of the release of [3H]‐acetylcholine ([3H]‐ACh) induced by tityustoxin, K+ 50 mm and…”
Get full text

Prolactin levels in drug-naïve first episode nonaffective psychosis patients compared with healthy controls. Sex differences by Del Cacho, N., Butjosa, A., Vila-Badia, R., Cuadras, D., Kaplan, M., Rubio-Abadal, E., Pardo, M., Muñoz-Samons, D., Cuevas-Esteban, J., Saenz- Navarrete, G., Usall, J.

“…•First episode drug-naïve psychotic patients had significantly elevated prolactin levels compared to healthy controls.•Significant differences in prolactin…”
Get full text

Depressive symptoms and their relationship with negative and other psychotic symptoms in early onset psychosis by Calderon-Mediavilla, María, Vila-Badia, Regina, Dolz, Montse, Butjosa, Anna, Barajas, Ana, Del Cacho, Nuria, Sánchez, Bernardo, Pardo, Marta, Baños, Iris, Usall, Judith, Ochoa, Susana

“…The importance of depression in adult people with first-episode psychosis (FEP) has been demonstrated. However, it has hardly been studied in children and…”
Get full text