Search Results - "Casal, Margarida"
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Adapting to survive: How Candida overcomes host-imposed constraints during human colonization
Published in PLoS pathogens (01-05-2020)“…Successful human colonizers such as Candida pathogens have evolved distinct strategies to survive and proliferate within the human host. These include…”
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Role of monocarboxylate transporters in human cancers: state of the art
Published in Journal of bioenergetics and biomembranes (01-02-2012)“…Monocarboxylate transporters (MCTs) belong to the SLC16 gene family, presently composed by 14 members. MCT1-MCT4 are proton symporters, which mediate the…”
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3
A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis
Published in The Journal of cell biology (23-01-2012)“…Endocytosis regulates the plasma membrane protein landscape in response to environmental cues. In yeast, the endocytosis of transporters depends on their…”
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4
Production and purification of two bioactive antimicrobial peptides using a two-step approach involving an elastin-like fusion tag
Published in Pharmaceuticals (Basel, Switzerland) (23-09-2021)“…Antimicrobial resistance is an increasing global threat, demanding new therapeutic biomolecules against multidrug-resistant bacteria. Antimicrobial peptides…”
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SATP (YaaH), a succinate-acetate transporter protein in Escherichia coli
Published in Biochemical journal (15-09-2013)“…In the present paper we describe a new carboxylic acid transporter in Escherichia coli encoded by the gene yaaH. In contrast to what had been described for…”
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Endocytosis of nutrient transporters in fungi: The ART of connecting signaling and trafficking
Published in Computational and structural biotechnology journal (01-01-2021)“…[Display omitted] Plasma membrane transporters play pivotal roles in the import of nutrients, including sugars, amino acids, nucleobases, carboxylic acids, and…”
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Genetic diversity and population structure of Saccharomyces cerevisiae strains isolated from different grape varieties and winemaking regions
Published in PloS one (29-02-2012)“…We herein evaluate intraspecific genetic diversity of fermentative vineyard-associated S. cerevisiae strains and evaluate relationships between grape varieties…”
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Glucose Metabolism as a Potential Therapeutic Target in Cytarabine-Resistant Acute Myeloid Leukemia
Published in Pharmaceutics (01-04-2024)“…Altered glycolytic metabolism has been associated with chemoresistance in acute myeloid leukemia (AML). However, there are still aspects that need…”
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Expanding the knowledge on the skillful yeast Cyberlindnera jadinii
Published in Journal of fungi (Basel) (09-01-2021)“…Cyberlindnera jadinii is widely used as a source of single-cell protein and is known for its ability to synthesize a great variety of valuable compounds for…”
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10
The dicarboxylate transporters from the AceTr family and Dct-02 oppositely affect succinic acid production in S. cerevisiae
Published in Journal of fungi (Basel) (06-08-2022)“…Membrane transporters are important targets in metabolic engineering to establish and improve the production of chemicals such as succinic acid from renewable…”
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Lactic acid production in Saccharomyces cerevisiae is modulated by expression of the monocarboxylate transporters Jen1 and Ady2
Published in FEMS yeast research (01-05-2012)“…Abstract We aimed to manipulate the metabolism of Saccharomyces cerevisiae to produce lactic acid and search for the potential influence of acid transport…”
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12
Biocomposites of Silk-Elastin and Essential Oil from Mentha piperita Display Antibacterial Activity
Published in ACS omega (01-03-2022)“…In this study, novel antimicrobial biocomposite films comprising a genetically engineered silk-elastin protein polymer (SELP) and essential oil from Mentha…”
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13
The use of genetically modified Saccharomyces cerevisiae strains in the wine industry
Published in Applied microbiology and biotechnology (01-08-2005)“…In recent decades, science and food technology have contributed at an accelerated rate to the introduction of new products to satisfy nutritional,…”
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New insights into the acetate uptake transporter (AceTr) family: Unveiling amino acid residues critical for specificity and activity
Published in Computational and structural biotechnology journal (01-01-2021)“…[Display omitted] •Substrate specificity of Ato1 was engineered by altering its pore size.•The L219A and F98A substitutions enable succinic acid transport…”
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15
Yeast Plasma Membrane Fungal Oligopeptide Transporters Display Distinct Substrate Preferences despite Their High Sequence Identity
Published in Journal of fungi (Basel) (12-11-2021)“…Fungal Oligopeptide Transporters (Fot) Fot1, Fot2 and Fot3 have been found in Saccharomyces cerevisiae wine strains, but not in strains from other…”
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Tailoring cutinase activity towards polyethylene terephthalate and polyamide 6,6 fibers
Published in Journal of biotechnology (10-03-2007)“…Cutinase from Fusarium solani pisi was genetically modified near the active site, by site-directed mutagenesis, to enhance its activity towards polyethylene…”
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Protein-engineered polymers functionalized with antimicrobial peptides for the development of active surfaces
Published in Applied sciences (09-06-2021)“…Antibacterial resistance is a major worldwide threat due to the increasing number of infections caused by antibiotic-resistant bacteria with medical devices…”
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Transcriptional responses of Candida glabrata biofilm cells to fluconazole are modulated by the carbon source
Published in NPJ biofilms and microbiomes (2020)“…The datasets generated in this study are available at public repositories or from the corresponding author upon request. The raw RNA-seq data in fastq format,…”
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Uncovering novel plasma membrane carboxylate transporters in the yeast Cyberlindnera jadinii
Published in Journal of fungi (Basel) (05-01-2022)“…The yeast Cyberlindnera jadinii has great potential in the biotechnology industry due to its ability to produce a variety of compounds of interest, including…”
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20
Survey of molecular methods for the typing of wine yeast strains
Published in FEMS microbiology letters (09-02-2004)“…A survey of the genetic polymorphisms produced by distinct methods was performed in 23 commercial winery yeast strains. Microsatellite typing, using six…”
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