Search Results - "Casal, Carme"
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1
Aged lipid‐laden microglia display impaired responses to stroke
Published in EMBO molecular medicine (08-02-2023)“…Microglial cells of the aged brain manifest signs of dysfunction that could contribute to the worse neurological outcome of stroke in the elderly. Treatment…”
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2
Human α-synuclein overexpression in mouse serotonin neurons triggers a depressive-like phenotype. Rescue by oligonucleotide therapy
Published in Translational psychiatry (24-02-2022)“…Anxiety and depression affect 35–50% of patients with Parkinson’s disease (PD), often precede the onset of motor symptoms, and have a negative impact on their…”
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3
Inhibition of Gsk3b Reduces Nfkb1 Signaling and Rescues Synaptic Activity to Improve the Rett Syndrome Phenotype in Mecp2-Knockout Mice
Published in Cell reports (Cambridge) (08-05-2018)“…Rett syndrome (RTT) is the second leading cause of mental impairment in girls and is currently untreatable. RTT is caused, in more than 95% of cases, by…”
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4
Astrocytes enhance lipopolysaccharide-induced nitric oxide production by microglial cells
Published in The European journal of neuroscience (01-10-2002)“…Several stimuli result in glial activation and induce nitric oxide (NO) production in microglial and astroglial cells. The bacterial endotoxin…”
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5
Effects of β-AP peptides on activation of the transcription factor NF-κB and in cell proliferation in glial cell cultures
Published in Neuroscience research (01-03-2004)“…The effect of two beta amyloid peptides (Aβ 25/35 and Aβ 1/42) on the activation of the transcription factor kappaB (NF-κB) in pure astroglial, pure microglial…”
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6
Dysferlin interacts with calsequestrin-1, myomesin-2 and dynein in human skeletal muscle
Published in The international journal of biochemistry & cell biology (01-08-2013)“…•FLIM–FRET analysis allows us to distinguish direct from indirect interactions.•FLIM–FRET analysis can be performed in native conditions.•Our findings will…”
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Effects of beta-AP peptides on activation of the transcription factor NF-kappaB and in cell proliferation in glial cell cultures
Published in Neuroscience research (01-03-2004)“…The effect of two beta amyloid peptides (Abeta 25/35 and Abeta 1/42) on the activation of the transcription factor kappaB (NF-kappaB) in pure astroglial, pure…”
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8
Relationship between β-AP peptide aggregation and microglial activation
Published in Brain research (22-02-2002)“…We compared the relationship between the state of aggregation of two peptides (β-AP 25-35 and β-AP 1-42) and microglial activation. After 7 days at 37 °C β-AP…”
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9
Role of calmodulin in the differentiation/activation of microglial cells
Published in Brain research (25-05-2001)“…In the present work the role of calmodulin (CaM) in regulating lipopolysaccharide (LPS)-induced microglial activation and in the spontaneous microglial…”
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