Search Results - "Casado‐Bedmar, Maite"
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The Effect of Sex-Specific Differences on IL-10 -/- Mouse Colitis Phenotype and Microbiota
Published in International journal of molecular sciences (01-06-2023)“…Sexual dimorphism is an important factor in understanding various diseases, including inflammatory bowel disease (IBD). While females typically exhibit…”
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The intestinal barrier function and its involvement in digestive disease
Published in Revista española de enfermedades digestivas (01-11-2015)“…The gastrointestinal mucosal surface is lined with epithelial cells representing an effective barrier made up with intercellular junctions that separate the…”
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Potential neuro-immune therapeutic targets in irritable bowel syndrome
Published in Therapeutic Advances in Gastroenterology (2020)“…Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disorder characterized by recurring abdominal pain and disturbed bowel habits. The…”
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Book Review Journal Article -
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Altered interaction between enteric glial cells and mast cells in the colon of women with irritable bowel syndrome
Published in Neurogastroenterology and motility (01-11-2021)“…Background Enteric glial cells (EGC) and mast cells (MC) are intimately associated with gastrointestinal physiological functions. We aimed to investigate…”
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Upregulation of intestinal mucosal mast cells expressing VPAC1 in close proximity to vasoactive intestinal polypeptide in inflammatory bowel disease and murine colitis
Published in Neurogastroenterology and motility (01-03-2019)“…Background Mast cells (MCs) and vasoactive intestinal polypeptide (VIP) have been proposed as regulators of the intestinal barrier and inflammation. Our aim…”
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Elevated F‐EDN correlates with mucosal eosinophil degranulation in patients with IBS—A possible association with microbiota?
Published in Journal of leukocyte biology (01-03-2022)“…Eosinophils have been linked to functional dyspepsia; however, less is known about their role in irritable bowel syndrome (IBS). This study tested the…”
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Fecal let-7b and miR-21 directly modulate the intestinal microbiota, driving chronic inflammation
Published in Gut microbes (31-12-2024)“…Inflammatory bowel diseases (IBD) etiology is multifactorial. Luminal microRNAs (miRNAs) have been suspected to play a role in the promotion of chronic…”
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Entamoeba muris mitigates metabolic consequences of high-fat diet in mice
Published in Gut microbes (31-12-2024)“…Metabolic syndrome (MetS) is a cluster of several human conditions including abdominal obesity, hypertension, dyslipidemia, and hyperglycemia, all of which are…”
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In Vitro Maturation of Cumulus-Oocyte Complexes and In Vitro Sperm Capacitation Significantly Increase the Expression and Enhance the Location of the CXCL12 and CXCR4 Anchoring Attractant Complex in Pigs
Published in Animals (Basel) (01-01-2021)“…Successful internal fertilization in mammals depends on several mechanisms, including those triggering the so-called "sperm attraction" towards the oocyte,…”
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MicroRNA and Gut Microbiota: Tiny but Mighty—Novel Insights into Their Cross-talk in Inflammatory Bowel Disease Pathogenesis and Therapeutics
Published in Journal of Crohn's and colitis (14-07-2022)“…Abstract MicroRNAs [miRNAs], small non-coding RNAs, have recently been described as crucial contributors to intestinal homeostasis. They can interact with the…”
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microRNA and gut microbiota: Tiny but mighty - Novel insights of their crosstalk in inflammatory bowel disease pathogenesis and therapeutics
Published in Journal of Crohn's and colitis (16-12-2021)“…MicroRNAs (miRNAs), small non-coding RNAs, have recently been described as crucial contributors to intestinal homeostasis. They can interact with the gut…”
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Vasoactive Intestinal Polypeptide and Mast Cells Regulate Increased Passage of Colonic Bacteria in Patients With Irritable Bowel Syndrome
Published in Gastroenterology (New York, N.Y. 1943) (01-10-2017)“…Irritable bowel syndrome (IBS) is associated with intestinal dysbiosis and symptoms of IBS develop following gastroenteritis. We aimed to study the passage of…”
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Increased Colonic Epithelial Permeability and Mucosal Eosinophilia in Ulcerative Colitis in Remission Compared With Irritable Bowel Syndrome and Health
Published in Inflammatory bowel diseases (18-06-2020)“…Abstract Background Barrier dysfunction is recognized as a pathogenic factor in ulcerative colitis (UC) and irritable bowel syndrome (IBS), but it is unclear…”
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A β-Glucan-Based Dietary Fiber Reduces Mast Cell-Induced Hyperpermeability in Ileum From Patients With Crohn's Disease and Control Subjects
Published in Inflammatory bowel diseases (01-01-2018)“…Abstract Background Administration of β-glucan has shown immune-enhancing effects. Our aim was to investigate whether β-glucan could attenuate mast cell…”
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A ß-Glucan-Based Dietary Fiber Reduces Mast Cell-Induced Hyperpermeability in Ileum From Patients With Crohns Disease and Control Subjects
Published in Inflammatory bowel diseases (2018)“…Administration of ß-glucan has shown immune-enhancing effects. Our aim was to investigate whether ß-glucan could attenuate mast cell (MC)-induced…”
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