Search Results - "Carvalho de Souza, Renata C."

Application of multicomponent reactions to antimalarial drug discovery. Part 2: New antiplasmodial and antitrypanosomal 4-aminoquinoline γ- and δ-lactams via a ‘catch and release’ protocol by Musonda, Chitalu C., Gut, Jiri, Rosenthal, Philip J., Yardley, Vanessa, Carvalho de Souza, Renata C., Chibale, Kelly

“…A parallel synthesis of a new series of 4-aminoquinoline γ- and δ-lactams synthesized via the Ugi 3-component 4-centre multicomponent reaction is described…”
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Antiplasmodial, beta-haematin inhibition, antitrypanosomal and cytotoxic activity in vitro of novel 4-aminoquinoline 2-imidazolines by Musonda, Chitalu C, Yardley, Vanessa, de Souza, Renata C Carvalho, Ncokazi, Kanyile, Egan, Timothy J, Chibale, Kelly

“…A novel series of 4-aminoquinoline-containing 2-imidazolines were synthesized via a one-pot 3-component condensation reaction of amine, aldehyde and…”
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