Search Results - "Carvalho, Magda Oliveira Seixas"
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Hydroxyurea alters hematological, biochemical and inflammatory biomarkers in Brazilian children with SCA: Investigating associations with βS haplotype and α-thalassemia
Published in PloS one (15-07-2019)“…This study investigated the effects of hydroxyurea (HU) on hematological, biochemical and inflammatory parameters in children with sickle cell anemia (SCA) in…”
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Sickle Cell Anemia Patients in Use of Hydroxyurea: Association between Polymorphisms in Genes Encoding Metabolizing Drug Enzymes and Laboratory Parameters
Published in Disease markers (01-01-2018)“…This study investigated associations between SNPs in genes encoding metabolizing drug enzymes and laboratory parameters in sickle cell anemia patients under…”
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3
Evaluation of Alpha-1 Antitrypsin Levels and SERPINA1 Gene Polymorphisms in Sickle Cell Disease
Published in Frontiers in immunology (06-11-2017)“…Alpha-1 antitrypsin (AAT) is an inhibitor of neutrophil elastase and a member of the serine proteinase inhibitor (serpin) superfamily, and little is known…”
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4
Ionic imbalance and lack of effect of adjuvant treatment with methylene blue in the hamster model of leptospirosis
Published in Memórias do Instituto Oswaldo Cruz (01-06-2013)“…Leptospirosis in humans usually involves hypokalaemia and hypomagnesaemia and the putative mechanism underlying such ionic imbalances may be related to nitric…”
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5
Serum haptoglobin and hemopexin levels are depleted in pediatric sickle cell disease patients
Published in Blood cells, molecules, & diseases (01-09-2018)Get full text
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Role of paraoxonase 1 activity and PON1 gene polymorphisms in sickle cell disease
Published in Scientific reports (03-05-2023)“…Sickle cell disease (SCD) patients often exhibit a dyslipidemic sub-phenotype. Paraoxonase 1 (PON 1) is a serum glycoprotein associated with the high-density…”
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Artigo de revisão: Uso da ATS na tomada de decisões nas análises clínicas - uma revisão sistemática
Published in Jornal de Assistência Farmacêutica e Farmacoeconomia (03-10-2022)“…Introdução: A avaliação de tecnologias em saúde (ATS) de dispositivos médicos é desafiadora. Apesar de ser uma área com tecnologias que podem ser dispendiosas…”
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8
Leptin −2548 G>A gene polymorphism is associated with lipids metabolism and TGF-β alteration in sickle cell disease
Published in Meta Gene (01-12-2016)“…Leptin is a protein with regulatory role in several body systems such as the immune system, and energy balance. Given that patients with sickle cell disease…”
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Hydroxyurea alters hematological, biochemical and inflammatory biomarkers in Brazilian children with SCA: Investigating associations with [beta]S haplotype and [alpha]-thalassemia
Published in PloS one (15-07-2019)“…This study investigated the effects of hydroxyurea (HU) on hematological, biochemical and inflammatory parameters in children with sickle cell anemia (SCA) in…”
Get full text
Journal Article -
10
Sickle Cell Inflammatory Environment Is Associated with Products of the Eicosanoid Synthesis Pathways
Published in Blood (03-12-2015)“…Background: Sickle cell disease (SCD) is a group of inherited anemia characterized by heterogeneous clinical outcome, including hemolysis, chronic…”
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Heme Concentration As a Biomarker of Sickle Cell Disease Severity: Its Role in Steady-State and in Crisis Patients
Published in Blood (03-12-2015)“…Background: Sickle cell disease (SCD) is a heredity group of anemia characterized by hemolysis, chronic inflammation, and vaso-occlusive/painful crisis. The…”
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Serum Haptoglobin and Hemopexin Levels in Pediatric SS and SC Disease Patients: Biomarker of Hemolysis and Inflammation
Published in Blood (02-12-2016)“…▪ INTRODUCTION: Hemolysis is a hallmark of sickle cell disease (SCD) pathogenesis, with the release of hemoglobin (Hb) and heme into the plasma that can…”
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13
Alpha-1 Antitrypsin and SERPINA1 gene Mutation As New Biomarker in Sickle Cell Disease
Published in Blood (06-12-2014)“…Sickle cell disease (SCD) has heterogeneous clinical picture and there are several pathway involved in SCD pathogenesis, and chronic inflammation and hemolysis…”
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14
Ionic imbalance and lack of effect of adjuvant treatment with methylene blue in the hamster model of leptospirosis
Published in Memórias do Instituto Oswaldo Cruz (15-01-2014)“…Leptospirosis in humans usually involves hypokalaemia and hypomagnesaemia and the putative mechanism underlying such ionic imbalances may be related to nitric…”
Get full text
Journal Article -
15
Ionic imbalance and lack of effect of adjuvant treatment with methylene blue in the hamster model of leptospirosis
Published in Memórias do Instituto Oswaldo Cruz (01-06-2013)“…Leptospirosis in humans usually involves hypokalaemia and hypomagnesaemia and the putative mechanism underlying such ionic imbalances may be related to nitric…”
Get full text
Journal Article