Search Results - "Carvalho, Leonardo José Moura"

Vascular dysfunction as a target for adjuvant therapy in cerebral malaria by Carvalho, Leonardo José de Moura, da Silva Moreira, Aline, Daniel-Ribeiro, Cláudio Tadeu, Martins, Yuri Chaves

“…Cerebral malaria (CM) is a life-threatening complication of Plasmodium falciparum malaria that continues to be a major global health problem. Brain vascular…”
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Lisinopril increases lung ACE2 levels and SARS-CoV-2 viral load and decreases inflammation but not disease severity in experimental COVID-19 by Silva-Santos, Yasmin, Pagni, Roberta Liberato, Gamon, Thais Helena Martins, de Azevedo, Marcela Santiago Pacheco, Bielavsky, Mônica, Darido, Maria Laura Goussain, de Oliveira, Danielle Bruna Leal, de Souza, Edmarcia Elisa, Wrenger, Carsten, Durigon, Edson Luiz, Luvizotto, Maria Cecília Rui, Ackerman, Hans Christian, Marinho, Claudio Romero Farias, Epiphanio, Sabrina, Carvalho, Leonardo José Moura

“…COVID-19 causes more severe and frequently fatal disease in patients with pre-existing comorbidities such as hypertension and heart disease. SARS-CoV-2 virus…”
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Long-term effect of uncomplicated Plasmodium berghei ANKA malaria on memory and anxiety-like behaviour in C57BL/6 mice by de Sousa, Luciana Pereira, de Almeida, Roberto Farina, Ribeiro-Gomes, Flávia Lima, de Moura Carvalho, Leonardo José, E Souza, Tadeu Mello, de Souza, Diogo Onofre Gomes, Daniel-Ribeiro, Cláudio Tadeu

“…Cerebral malaria, the main complication of Plasmodium falciparum infection in humans, is associated with persistent neurocognitive sequels both in human…”
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Similar Cytokine Responses and Degrees of Anemia in Patients with Plasmodium falciparum and Plasmodium vivax Infections in the Brazilian Amazon Region by Fernandes, Andréa Aparecida Morais, Carvalho, Leonardo José de Moura, Zanini, Graziela Maria, Ventura, Ana Maria Revorêdo da Silva, Souza, José Maria, Cotias, Paulo Marcelo, Silva-Filho, Isaac Lima, Daniel-Ribeiro, Cláudio Tadeu

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Inflammatory changes in the central nervous system are associated with behavioral impairment in Plasmodium berghei (strain ANKA)-infected mice by Lacerda-Queiroz, Norinne, Rodrigues, David Henrique, Vilela, Márcia Carvalho, Miranda, Aline Silva de, Amaral, Débora Cristina Guerra, Camargos, Elizabeth Ribeiro da Silva, Carvalho, Leonardo José de Moura, Howe, Charles L, Teixeira, Mauro Martins, Teixeira, Antônio Lúcio

“…Experimental cerebral malaria is a neuroinflammatory condition that results from the host immune response to the parasite. Using intravital microscopy, we…”
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L‐arginine Supplementation and Thromboxane Synthase Inhibition Reverse Cerebral Ischemia in Murine Cerebral Malaria by Plasmodium berghei ANKA by Silva Moreira, Aline, Freitas Almeida, Vanessa Estato, Bianco‐Júnior, Cesare, Daniel‐Ribeiro, Claudio Tadeu, Tibiriçá, Eduardo Vera, Moura Carvalho, Leonardo José

“…Cerebral malaria (CM) is one of the most severe and lethal complications of Plasmodium falciparum infection. The mainstay treatment for CM is intravenous…”
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Virulence Profiles of Wild-Type, P.1 and Delta SARS-CoV-2 Variants in K18-hACE2 Transgenic Mice by da Silva Santos, Yasmin, Gamon, Thais Helena Martins, de Azevedo, Marcela Santiago Pacheco, Telezynski, Bruna Larotonda, de Souza, Edmarcia Elisa, de Oliveira, Danielle Bruna Leal, Dombrowski, Jamille Gregório, Rosa-Fernandes, Livia, Palmisano, Giuseppe, de Moura Carvalho, Leonardo José, Luvizotto, Maria Cecília Rui, Wrenger, Carsten, Covas, Dimas Tadeu, Curi, Rui, Marinho, Claudio Romero Farias, Durigon, Edison Luiz, Epiphanio, Sabrina

“…Since December 2019, the world has been experiencing the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and we…”
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Increased Neutrophil Percentage and Neutrophil-T Cell Ratio Precedes Clinical Onset of Experimental Cerebral Malaria by Freire-Antunes, Lucas, Ornellas-Garcia, Uyla, Rangel-Ferreira, Marcos Vinicius, Ribeiro-Almeida, Mônica Lucas, de Sousa, Carina Heusner Gonçalves, Carvalho, Leonardo José de Moura, Daniel-Ribeiro, Cláudio Tadeu, Ribeiro-Gomes, Flávia Lima

“…Newly emerging data suggest that several neutrophil defense mechanisms may play a role in both aggravating and protecting against malaria. These exciting…”
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Immunomodulation through vaccination as a promising therapeutic strategy to mitigate malaria-related neurocognitive sequelae by Rosa-Gonçalves, Pamela, de Sousa, Luciana Pereira, Ribeiro-Gomes, Flávia Lima, Carvalho, Leonardo José Moura, Daniel-Ribeiro, Cláudio Tadeu

“…•Malaria is a systemic and potentially neuroinflammatory parasitic disease.•Even in its non-severe form (nSM), malaria may evolve to neurocognitive…”
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Chloroquine and mefloquine resistance profiles are not related to the circumsporozoite protein (CSP) VK210 subtypes in field isolates of Plasmodium vivax from Manaus, Brazilian Amazon by Pratt-Riccio, Lilian Rose, Baptista, Bárbara de Oliveira, Torres, Vanessa Rodrigues, Bianco-Junior, Cesare, Perce-Da-Silva, Daiana de Souza, Riccio, Evelyn Kety Pratt, Lima-Junior, Josué da Costa, Totino, Paulo Renato Rivas, Cassiano, Gustavo Capatti, Storti-Melo, Luciane Moreno, Machado, Ricardo Luiz Dantas, de Oliveira-Ferreira, Joseli, Banic, Dalma Maria, Carvalho, Leonardo José de Moura, Daniel-Ribeiro, Cláudio Tadeu

“…The central repetitive region (CRR) of the Plasmodium vivax circumsporozoite surface protein (CSP) is composed of a repetitive sequence that is characterised…”
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Characterization of cerebral malaria in the outbred Swiss Webster mouse infected by Plasmodium berghei ANKA by Martins, Yuri Chaves, Smith, Mary Jane, Pelajo-Machado, Marcelo, Werneck, Guilherme Loureiro, Lenzi, Henrique Leonel, Daniel-Ribeiro, Claudio Tadeu, Carvalho, Leonardo José de Moura

“…Summary Plasmodium berghei ANKA (PbA) infection in susceptible inbred mouse strains is the most commonly used experimental model to study pathogenesis of…”
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Challenges in the determination of early predictors of cerebral malaria: lessons from the human disease and the experimental murine models by Martins, Yuri Chaves, Carvalho, Leonardo José de Moura, Daniel-Ribeiro, Cláudio Tadeu

“…Cerebral malaria (CM) is a life-threatening complication of malaria caused by Plasmodium falciparum, and it claims around two million lives a year, mainly…”
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Sera of patients with systemic lupus erythematosus react with plasmodial antigens and can inhibit the in vitro growth of Plasmodium falciparum by Zanini, Graziela Maria, De Moura Carvalho, Leonardo José, Brahimi, Karima, De Souza-Passos, Luiz Fernando, Guimarães, Swami José, Da Silva Machado, Eduardo, Bianco-Junior, Cesare, Riccio, Evelyn Kety Pratt, De Sousa, Maria Auxiliadora, Alecrim, Maria Das Graças Costa, Leite, Nocy, Druilhe, Pierre, Daniel-Ribeiro, Claudio Tadeu

“…The acquisition of protective immunity in malaria is a slow process during which autoantibodies are produced. The present work aimed at studying a possible…”
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Antibodies against the Plasmodium falciparum glutamate-rich protein from naturally exposed individuals living in a Brazilian malaria-endemic area can inhibit in vitro parasite growth by Pratt-Riccio, Lilian Rose, Bianco, Jr, Cesare, Totino, Paulo Renato Rivas, Perce-Da-Silva, Daiana De Souza, Silva, Luciene Aquino, Riccio, Evelyn Kety Pratt, Ennes-Vidal, Vítor, Neves-Ferreira, Ana Gisele Costa, Perales, Jonas, Da Rocha, Surza Lucia Gonçalves, Dias-Da-Silva, Fabrício, Ferreira-da-Cruz, Maria de Fátima, Daniel-Ribeiro, Cláudio Tadeu, De Oliveira-Ferreira, Joseli, Theisen, Michael, Carvalho, Leonardo José De Moura, Banic, Dalma Maria

“…The glutamate-rich protein (GLURP) is an exoantigen expressed in all stages of the Plasmodium falciparum life cycle in humans. Anti-GLURP antibodies can…”
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Antibodies against the Plasmodium falciparum glutamate-rich protein from naturally exposed individuals living in a Brazilian malaria-endemic area can inhibit in vitro parasite growth by Pratt-Riccio, Lilian Rose, Bianco-Junior, Cesare, Totino, Paulo Renato Rivas, Perce-Da-Silva, Daiana De Souza, Silva, Luciene Aquino, Riccio, Evelyn Kety Pratt, Ennes-Vidal, Vítor, Neves-Ferreira, Ana Gisele Costa, Perales, Jonas, Da Rocha, Surza Lucia Gonçalves, Dias-Da-Silva, Fabrício, Ferreira-da-Cruz, Maria de Fátima, Daniel-Ribeiro, Cláudio Tadeu, De Oliveira-Ferreira, Joseli, Theisen, Michael, De Moura Carvalho, Leonardo José, Banic, Dalma Maria

“…The glutamate-rich protein (GLURP) is an exoantigen expressed in all stages of the Plasmodium falciparum life cycle in humans. Anti-GLURP antibodies can…”
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Vascular dysfunction as a target for adjuvant therapy in cerebral malaria by Carvalho, Leonardo José de Moura, Moreira, Aline da Silva, Daniel-Ribeiro, Cláudio Tadeu, Martins, Yuri Chaves

“…Cerebral malaria (CM) is a life-threatening complication of Plasmodium falciparum malaria that continues to be a major global health problem. Brain vascular…”
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Aspartate aminotransferase-to-platelet ratio index by Guedes, Karla Sena, Sanchez, Bruno Antônio Marinho, Gomes, Luciano Teixeira, Fontes, Cor Jesus Fernandes, Carvalho, Leonardo Jose de Moura

“…Acute infection with Plasmodium vivax, classically associated with benign disease, has been presenting as serious and even fatal disease in recent years…”
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Aspartate aminotransferase-to-platelet ratio index (APRI): A potential marker for diagnosis in patients at risk of severe malaria caused by Plasmodium vivax by Guedes, Karla Sena, Sanchez, Bruno Antônio Marinho, Gomes, Luciano Teixeira, Fontes, Cor Jesus Fernandes

“…Acute infection with Plasmodium vivax, classically associated with benign disease, has been presenting as serious and even fatal disease in recent years…”
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