Search Results - "Carvalho, João E. de"

Sulfonamide-containing copper(II) metallonucleases: Correlations with in vitro antimycobacterial and antiproliferative activities by Nakahata, Douglas H., de Paiva, Raphael E.F., Lustri, Wilton R., Ribeiro, Camila M., Pavan, Fernando R., da Silva, Gisele G., Ruiz, Ana L.T.G., de Carvalho, João E., Corbi, Pedro P.

“…The bis-(1,10-phenanthroline)copper(I) complex, [Cu(I)(phen)2]+, was the first copper-based artificial nuclease reported in the literature. The biological and…”
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Diastereoselective Synthesis of Biologically Active Cyclopenta[b]indoles by Santos, Marilia S., Fernandes, Daniara C., Rodrigues, Manoel T., Regiani, Thais, Andricopulo, Adriano D., Ruiz, Ana Lúcia T. G., Vendramini-Costa, Débora B., de Carvalho, João E., Eberlin, Marcos N., Coelho, Fernando

“…The cyclopenta­[b]­indole motif is present in several natural and synthetic biologically active compounds, being directly responsible for the biological…”
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Antiproliferative Flavanoid Dimers Isolated from Brazilian Red Propolis by Banzato, Thais P, Gubiani, Juliana R, Bernardi, Darlon I, Nogueira, Cláudio R, Monteiro, Afif F, Juliano, Fernanda F, de Alencar, Severino M, Pilli, Ronaldo A, Lima, Carolina A. de, Longato, Giovanna B, Ferreira, Antonio G, Foglio, Mary Ann, Carvalho, João E. de, Vendramini-Costa, Débora B, Berlinck, Roberto G. S

“…Herein reported are results of the chemical and biological investigation of red propolis collected at the Brazilian Northeast coastline. New propolones A–D…”
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Coronarin D Induces Apoptotic Cell Death and Cell Cycle Arrest in Human Glioblastoma Cell Line by M Franco, Yollanda E, Y Okubo, Marcia, D Torre, Adriana, P Paiva, Paula, N Rosa, Marcela, O Silva, Viviane A, M Reis, Rui, T G Ruiz, Ana L, M Imamura, Paulo, de Carvalho, João E, B Longato, Giovanna

“…Glioblastoma (GBM) is the most frequent and highest-grade brain tumor in adults. The prognosis is still poor despite the use of combined therapy involving…”
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Free radical scavenging and antiproliferative properties of Biginelli adducts by da Silva, Daniel L., Reis, Fabiano S., Muniz, Dandara R., Ruiz, Ana Lúcia T.G., de Carvalho, João E., Sabino, Adão A., Modolo, Luzia V., de Fátima, Ângelo

“…A series of Biginelli adducts bearing different substituents at C-4 position were synthesized by using p-sulfonic acid calix[4]arene as a catalyst. The in…”
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Enhanced resolution and speckle‐free three‐dimensional printing of macular optical coherence tomography angiography by Maloca, Peter M., Spaide, Richard F., Rothenbuehler, Simon, Scholl, Hendrik P. N., Heeren, Tjebo, Ramos de Carvalho, João E., Okada, Mali, Hasler, Pascal W., Egan, Catherine, Tufail, Adnan

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CHEMICAL CONSTITUENTS AND EVALUATION OF ANTIPROLIFERATIVE AND ANTI-INFLAMMATORY ACTIVITIES FROM Psychotria schlechtendaliana (RUBIACEAE) by Corrêa, José, de Moura, Vagner, Ames, Franciele, Bianchin, Mirelli, Sebold, Simone, Peixoto, Matheus, Pomini, Armando, de Carvalho, João, Ruiz, Ana, Bersani-Amado, Ciomar, Santin, Silvana

“…Phytochemical study of Psychotria schlechtendaliana (Rubiaceae) aerial parts resulted in the isolation of alkaloids 4-N-oxide harmane (1) and strictosidinic…”
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Antioxidative, Antiproliferative and Antimicrobial Activities of Phenolic Compounds from Three Myrcia Species by Dos Santos, Catarina, Galaverna, Renan S, Angolini, Celio F F, Nunes, Vania V A, de Almeida, Luiz F R, Ruiz, Ana L T G, de Carvalho, João E, Duarte, Regina M T, Duarte, Marta C T, Eberlin, Marcos N

“…Cambess., (Rich.) DC. and (Aubl.) DC. (Myrtaceae) are trees found in Brazilian Cerrado. They have been widely used in folk medicine for the treatment of…”
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Total Synthesis of (+)-trans-Trikentrin A by Tébéka, Iris R. M., Longato, Giovanna B., Craveiro, Marcus V., de Carvalho, João E., Ruiz, Ana L. T. G., Silva Jr, Luiz F.

“…Several syntheses have already been reported for cis‐trikentrins and herbindoles, which are indole alkaloids unsubstituted at the C2 and C3 positions that bear…”
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Structural Characterization and Biological Evaluation of 18‐Nor‐ent‐labdane Diterpenoids from Grazielia gaudichaudeana by Balbinot, Rodolfo B., de Oliveira, Josiane A. M., Bernardi, Darlon I., Melo, Ulisses Z., Zanqueta, Érica B., Endo, Eliana H., Ribeiro, Fabianne M., Volpato, Hélito, Figueiredo, Mariana C., Back, Davi F., Basso, Ernani A., Ruiz, Ana L. T. G., de Carvalho, João E., Foglio, Mary Ann, Prado Filho, Benedito D., Nakamura, Tania U., Nakamura, Celso V., do Carmo, Marta R. B., Sarragiotto, Maria H., Baldoqui, Debora C.

“…The phytochemical investigation of Grazielia gaudichaudeana aerial parts yielded 15 compounds, including diterpenes, triterpenes, sterols and flavonoids. With…”
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Populene D analogues: design, concise synthesis and antiproliferative activity by Reddy, Kachi R Kishore Kumar, Longato, Giovanna B, de Carvalho, João E, Ruiz, Ana L T G, Silva, Jr, Luiz F

“…An efficient and concise synthesis of nine populene D analogues was performed using an iodine-catalyzed Prins cyclization as the key transformation. The…”
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Antiproliferative Activity of Flavonoids from Croton sphaerogynus Baill. (Euphorbiaceae) by Furlan, Cláudia M., Carvalho, João E. de, Lago, João Henrique G., Ferreira, Marcelo J. P., Salatino, A., Salatino, M. L. F., Santos, Deborah Y. A. C., Motta, Lucimar B., Santos, Kátia Pereira dos, Ruiz, Ana Lúcia Tasca Gois

“…Croton sphaerogynus is a shrub from the Atlantic Rain Forest in southeastern Brazil. A lyophilized crude EtOH extract from leaves of C. sphaerogynus, obtained…”
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Novel Bidentate Amine Ligand and the Interplay between Pd(II) and Pt(II) Coordination and Biological Activity by Oliveira, Laiane S., Rosa, Letícia B., Affonso, Daniele D., Santos, Igor A., Da Silva, Jennyfer C., Rodrigues, Gustavo C., Harris, Mark, Jardim, Ana Carolina G., Nakahata, Douglas H., Sabino, José R., Carvalho, João E., Miguel, Danilo C., Ruiz, Ana Lucia T. G., Abbehausen, Camilla

“…Pt(II) and Pd(II) coordinating N‐donor ligands have been extensively studied as anticancer agents after the success of cisplatin. In this work, a novel…”
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Studies on free radical scavenging, cancer cell antiproliferation, and calf thymus DNA interaction of Schiff bases by da Silva, Cleiton M., Silva, Marina M., Reis, Fabiano S., Ruiz, Ana Lúcia T.G., de Carvalho, João E., Santos, Josué C.C., Figueiredo, Isis M., Alves, Rosemeire B., Modolo, Luzia V., de Fátima, Ângelo

“…Thirty-nine Schiff bases were synthesized by performing microwave-assisted condensation of the corresponding aldehydes and aromatic amines. Their reactive…”
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Novel R-(+)-limonene-based thiosemicarbazones and their antitumor activity against human tumor cell lines by Vandresen, Fábio, Falzirolli, Hugo, Almeida Batista, Sabrina A., da Silva-Giardini, Ana Paula B., de Oliveira, Diogo N., Catharino, Rodrigo R., Ruiz, Ana Lúcia T.G., de Carvalho, João E., Foglio, Mary Ann, da Silva, Cleuza Conceição

“…In an attempt to develop potent and selective antitumor agents, a series of novel thiosemicarbazones derived from a natural monoterpene R-(+)-limonene was…”
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Synthesis and antiproliferative activity of 8-hydroxyquinoline derivatives containing a 1,2,3-triazole moiety by de O. Freitas, Luiza B., Borgati, Thiago F., de Freitas, Rossimiriam P., Ruiz, Ana L.T.G., Marchetti, Gabriela M., de Carvalho, João E., da Cunha, Elaine F.F., Ramalho, Teodorico C., Alves, Rosemeire B.

“…Twelve novel 8-hydroxyquinoline derivatives were synthesized with good yields by performing copper-catalyzed Huisgen 1,3-dipolar cycloaddition (“click”…”
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Polynuclear copper(II) complexes with nalidixic acid hydrazones: Antiproliferative activity and selectivity assessment over a panel of tumor cells by Bergamini, Fernando R.G., Nunes, Julia H.B., de Carvalho, Marcos A., Ribeiro, Marcos A., de Paiva, Paula P., Banzato, Thais P., Ruiz, Ana L.T.G., de Carvalho, João E., Lustri, Wilton R., Martins, Daniel O.T.A., da Costa Ferreira, Ana M., Corbi, Pedro P.

“…The selectivity of synthesized polynuclear copper(II) complexes with nalidixic acid hydrazone derivatives, as shown for complex 1A, [Cu2(C16H16N6O2)Cl4], and…”
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Cytotoxic activity of Guettarda pohliana Müll. Arg. (Rubiaceae) by de Oliveira, Paulo R.N., Testa, Gláucio, Medina, Rebeca P., de Oliveira, Cecília M.A., Kato, Lucilia, da Silva, Cleuza C., de Carvalho, João E., Santin, Silvana M.O.

“…The cytotoxic activity of crude extracts and their fractions from leaves and roots of G. pohliana was assessed against nine human cancer cell lines: melanoma…”
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Antiproliferative activity and chemical constituents of Lonchocarpus cultratus (Fabaceae) by da Silva Landim, Emanuelle M. B. M., Ruiz, Ana Lúcia T. G., de Carvalho, João E., Pomini, Armando M., Pastorini, Lindamir H., Oliveira Santin, Silvana M.

“…The aerial parts of L. cultratus were submitted to a phytopharmacological investigation in order to isolate and identify the major secondary metabolites and…”
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Derivatives of furanditerpenes from Pterodon genus: Pharmacological studies disclose their potential as chronic pain relief in mice by Spindola, Humberto M., Grando, Rogério, Figueiredo, Mariana C., Basting, Rosana, Queiroz, N.C.A., de Fátima, Ângelo, de Carvalho, João E., Wang, Zaijie J., Foglio, M.A.

“…Pterodon genus fruits are commercially available at the Brazilian medicinal market used in folk medicine due to their anti-inflammatory, analgesic, and…”
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