Search Results - "Carvalho, Flávia Chiva"

Mucoadhesive drug delivery systems by Carvalho, Flávia Chiva, Bruschi, Marcos Luciano, Evangelista, Raul Cesar, Gremião, Maria Palmira Daflon

“…Drug actions can be improved by developing new drug delivery systems, such as the mucoadhesive system. These systems remain in close contact with the…”
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Mucoadhesive nanostructured lipid carriers as a cannabidiol nasal delivery system for the treatment of neuropathic pain by Matarazzo, Ananda Pulini, Elisei, Lívia Maria Silvestre, Carvalho, Flávia Chiva, Bonfílio, Rudy, Ruela, André Luís Morais, Galdino, Giovane, Pereira, Gislaine Ribeiro

“…The therapeutic potential of cannabidiol (CBD) has been explored to treat several pathologies, including those in which pain is prevalent. However, the oral…”
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Rheological, mechanical, and bioadhesive behavior of hydrogels to optimize skin delivery systems by Carvalho, Flávia Chiva, Calixto, Giovana, Hatakeyama, Ilka Narita, Luz, Gabriela Marielli, Gremião, Maria Palmira Daflon, Chorilli, Marlus

“…Background: Hydrogels are widely used for cutaneous formulations; thereby comparing the bioadhesive properties of polymers with a view to prolong the residence…”
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Computational and experimental approaches for development of methotrexate nanosuspensions by bottom-up nanoprecipitation by dos Santos, Aline Martins, Carvalho, Flávia Chiva, Teixeira, Deiver Alessandro, Azevedo, David Lima, de Barros, Wander Miguel, Gremião, Maria Palmira Daflon

“…[Display omitted] •MTX nanosuspensions were obtained by bottom-up method based on acid-base reactions.•Computational modeling evaluated the mechanisms of MTX…”
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The liquid crystalline phase behaviour of a nasal formulation modifies the brain disposition of donepezil in rats in the treatment of Alzheimer's disease by de Souza, Isabelly Fernanda Ferraz, dos Santos, Thaís Queiroz, Placido, Rodrigo Vicentino, Mangerona, Bianca Aparecida, Carvalho, Flávia Chiva, Boralli, Vanessa Bergamin, Ruela, André Luís Morais, Pereira, Gislaine Ribeiro

“…[Display omitted] •A microemulsion (ME) for the intranasal delivery of donepezil was obtained.•The ME undergoes an in situ phase transition to a mucoadhesive…”
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Nasal administration of liquid crystal precursor mucoadhesive vehicle as an alternative antiretroviral therapy by Carvalho, Flávia Chiva, Campos, Michel Leandro, Peccinini, Rosângela Gonçalves, Gremião, Maria Palmira Daflon

“…This study developed a low viscosity precursor of a liquid crystal phase to obtain a mucoadhesive stimuli-sensitive drug delivery system for nasal…”
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Exploring the Phase Behavior of Monoolein/Oleic Acid/Water Systems for Enhanced Donezepil Administration for Alzheimer Disease Treatment by Ruela, André Luís Morais, Carvalho, Flávia Chiva, Pereira, Gislaine Ribeiro

“…Donepezil is a drug usually administered by oral route for Alzheimer disease treatment, but several gastric side effects have been reported as diarrhea,…”
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Preclinical study of methotrexate-based hydrogels versus surfactant based liquid crystal systems on psoriasis treatment by Bernardes, Maria Tereza Carneiro Paschoal, Agostini, Sandra Barbosa Neder, Pereira, Gislaine Ribeiro, da Silva, Laíla Pereira, da Silva, Jéssica Bassi, Bruschi, Marcos Luciano, Novaes, Rômulo Dias, Carvalho, Flávia Chiva

“…Psoriasis is an autoimmune, inflammatory and chronic skin disease in which cell growth and proliferation are increased, causing erythema, lesions and skin's…”
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Adsorption and release of nicotine from imprinted particles synthesised by precipitation polymerisation: Optimising transdermal formulations by Ruela, André Luís Morais, de Figueiredo, Eduardo Costa, Carvalho, Flávia Chiva, de Araújo, Magali Benjamim, Pereira, Gislaine Ribeiro

“…[Display omitted] •Nicotine adsorption in the polymer particles was better fitted to Langmuir-Freundlich isotherm.•MIP-2 showed higher selective adsorption of…”
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Determination of dexamethasone acetate in CETETH 20‐based in liquid crystalline systems using HPLC by Oyafuso, Márcia Helena, Fonseca‐Santos, Bruno, Kogawa, Ana Carolina, Carvalho, Flávia Chiva, Gremião, Maria Palmira Daflon, Chorilli, Marlus

“…Dexamethasone acetate (DEX), a potent anti‐inflammatory, is used primarily in the treatment of inflammatory and autoimmune diseases. It was incorporated in…”
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Molecularly imprinted microparticles in lipid-based formulations for sustained release of donepezil by Ruela, André Luís Morais, de Figueiredo, Eduardo Costa, de Araújo, Magali Benjamim, Carvalho, Flávia Chiva, Pereira, Gislaine Ribeiro

“…Donepezil is a drug administered for Alzheimer's disease treatment, and it is a potential template molecule for imprinted microparticles. The precipitation…”
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Design and Characterization of Silicone and Surfactant Based Systems for Topical Drug Delivery by Oyafuso, Márcia Helena, Carvalho, Flávia Chiva, Chiavacci, Leila Aparecida, Gremião, Maria Palmira Daflon, Chorilli, Marlus

“…Nanotechnology offers advantages for new drug delivery design by providing drug targeting while minimizing the side effects. Polyoxyethylene 20 cetyl alcohol…”
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Preparation and Characterization of Chitosan Nanoparticles for Zidovudine Nasal Delivery by Barbi, Mariana Da Silva, Carvalho, Flávia Chiva, Kiill, Charlene Priscila, Barud, Hernane Da Silva, Santagneli, Sílvia Helena, Ribeiro, Sidney José Lima, Gremião, Maria Palmira Daflon

“…Zidovudine (AZT) is the antiretroviral drug most frequently used for the treatment of Acquired Immunodeficiency Syndrome. Its low oral bioavailability demands…”
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Preclinical Evaluation of Polymeric Nanocomposite Containing Pregabalin for Sustained Release as Potential Therapy for Neuropathic Pain by Rodrigues, Rafaela Figueiredo, Nunes, Juliana Barbosa, Agostini, Sandra Barbosa Neder, dos Santos, Paloma Freitas, Cancino-Bernardi, Juliana, Placido, Rodrigo Vicentino, Moraes, Thamyris Reis, Freitas, Jennifer Tavares Jacon, Pereira, Gislaine Ribeiro, Carvalho, Flávia Chiva, Galdino, Giovane, Boralli, Vanessa Bergamin

“…This study offers a novel oral pregabalin (PG)-loaded drug delivery system based on chitosan and hypromellose phthalate-based polymeric nanocomposite in order…”
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Influence of the ionic strength on the physicochemical properties of methotrexate-loaded chitosan polyelectrolyte complexes by Agostini, Sandra Barbosa Neder, Machado, Victor Lima de Sousa, Virtuoso, Luciano Sindra, Nogueira, Denismar Alves, Pereira, Gislaine Ribeiro, Carvalho, Flávia Chiva

“…Abstract Polyelectrolyte complexes (PECs) as drug delivery systems are widely explored since they are easily obtained by coacervation and biopolymers can be…”
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Development of Cutaneous Bioadhesive Ureasil-Polyether Hybrid Films by Chorilli, Marlus, Soares, Christiane Pienna, Carvalho, Flávia Chiva, Oshiro Junior, João Augusto, Chiavacci, Leila Aparecida

“…The hydrolysis and condensation reactions involved in synthesis of ureasil-polyether films influence the film formation time and the number of chemical groups…”
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Evaluation of polyelectrolyte and emulsion covalent crosslink of chitosan for producing mesalasine loaded submicron particles by Lacerda, Gabriel José Silveira, Piantino, Beatriz Lemos, Gonzaga, Edeilson Vitor, Naves, Valéria de Moura Leite, Pedreiro, Liliane Neves, Gremião, Maria Palmira Daflon, Pereira, Gislaine Ribeiro, Carvalho, Flávia Chiva

“…This study evaluates various techniques for producing mesalamine (5ASA)-loaded particles employing chitosan as a biopolymer: (1) the polyelectrolyte…”
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LC Evaluation of In Vitro Release of AZT from Microemulsions by Carvalho, Flávia Chiva, Barbi, Mariana da Silva, Gremião, Maria Palmira Daflon

“…A reversed phase LC method was developed and validated to analyze the in vitro release of AZT from microemulsions. A mobile phase of acetonitrile:water (15:85)…”
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Corrositex®, BCOP and HET-CAM as alternative methods to animal experimentation by Cazedey, Edith Cristina Laignier, Carvalho, Flávia Chiva, Fiorentino, Flávia Angélica Másquio, Gremião, Maria Palmira Daflon, Salgado, Hérida Regina Nunes

“…Tests in animals are used as models in toxicological and investigative studies. However, such tests have been considered inhumane because they can cause pain…”
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Evaluation of methotrexate-loaded surfactants, ceramides and cholesterol-based lamellar phases as a topical treatment for psoriasis by Alves, Cintia Oliveira, Novaes, Rômulo Dias, Bernardes, Maria Tereza Carneiro Paschoal, Gonçalves, Reggiani Vilela, da Silva, Laíla Pereira, Agostini, Sandra Barbosa Neder, Pereira, Gislaine Ribeiro, Carvalho, Flávia Chiva

“…Abstract Objective Psoriasis is a chronic inflammatory skin disorder. Oral or subcutaneous methotrexate (MTX) is a first-line antipsoriatic treatment, whose…”
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