Search Results - "Carvalho, Eva D."

Hydrogel-Assisted Antisense LNA Gapmer Delivery for In Situ Gene Silencing in Spinal Cord Injury by Moreno, Pedro M.D., Ferreira, Ana R., Salvador, Daniela, Rodrigues, Maria T., Torrado, Marília, Carvalho, Eva D., Tedebark, Ulf, Sousa, Mónica M., Amaral, Isabel F., Wengel, Jesper, Pêgo, Ana P.

“…After spinal cord injury (SCI), nerve regeneration is severely hampered due to the establishment of a highly inhibitory microenvironment at the injury site,…”
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The interplay between chemical conjugation and biologic performance in the development of alginate-based 3D matrices to mimic neural microenvironments by Carvalho, Eva D., Morais, Miguel R.G., Pêgo, Ana P., Barrias, Cristina C., Araújo, Marco

“…Biofunctionalization of polysaccharides is a widely used strategy for obtaining extracellular matrix (ECM)-mimicking biomaterials. Still, commonly employed…”
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A paradigm shift: Bioengineering meets mechanobiology towards overcoming remyelination failure by Carvalho, Eva D., Morais, Miguel R.G., Ferreira, Helena P., Silva, Mariana M.C., Guimarães, Sofia C., Pêgo, Ana P.

“…Therapeutic strategies aimed at overcoming the loss of myelin sheath in central nervous system demyelinating diseases are often unsuccessful due to nescience…”
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High-throughput platforms for the screening of new therapeutic targets for neurodegenerative diseases by Rocha, Daniela N., Carvalho, Eva D., Pêgo, Ana Paula

“…•Simple and robust readout methods are crucial to the success of an HTS platform.•Molecular gradients are important regulatory components of tissue…”
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High-throughput platforms for the screening of new therapeutic targets for neurodegenerative diseases: Foundation by Rocha, Daniela N, Carvalho, Eva D, Pego, Ana Paula

“…Despite the recent progress in the understanding of neurodegenerative disorders, a lack of solid fundamental knowledge on the etiology of many of the major…”
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