Search Results - "Carvalho, Antonio Carlos Campos de"
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Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice
Published in Nature communications (24-11-2016)“…Diabetes mellitus (DM) encompasses a multitude of secondary disorders, including heart disease. One of the most frequent and potentially life threatening…”
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2
Prevalence and impact of sarcopenia in individuals with heart failure with reduced ejection fraction (the SARC-HF study): A prospective observational study protocol
Published in PloS one (21-03-2024)“…Sarcopenia, a clinical syndrome primarily associated with reduced muscle mass in the elderly, has a negative impact on quality of life and survival. It can…”
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3
Tracking stem cells with superparamagnetic iron oxide nanoparticles: perspectives and considerations
Published in International Journal of Nanomedicine (01-01-2017)“…Superparamagnetic iron oxide nanoparticles (SPIONs) have been used for diagnoses in biomedical applications, due to their unique properties and their apparent…”
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Bone-Marrow-Derived Mesenchymal Stromal Cells (MSC) from Diabetic and Nondiabetic Rats Have Similar Therapeutic Potentials
Published in Arquivos brasileiros de cardiologia (01-12-2017)“…Diabetes mellitus is a severe chronic disease leading to systemic complications, including cardiovascular dysfunction. Previous cell therapy studies have…”
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5
Bone marrow cell migration to the heart in a chimeric mouse model of acute chagasic disease
Published in Memórias do Instituto Oswaldo Cruz (01-08-2017)“…Chagas disease is a public health problem caused by infection with the protozoan Trypanosoma cruzi. There is currently no effective therapy for Chagas disease…”
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6
Myosin-binding Protein C Compound Heterozygous Variant Effect on the Phenotypic Expression of Hypertrophic Cardiomyopathy
Published in Arquivos brasileiros de cardiologia (01-04-2017)“…Hypertrophic cardiomyopathy (HCM) is an autosomal dominant genetic disease caused by mutations in genes encoding sarcomere proteins. It is the major cause of…”
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Aging Triggers Mitochondrial Dysfunction in Mice
Published in International journal of molecular sciences (24-06-2023)“…Direct analysis of isolated mitochondria from old mice enables a better understanding of heart senescence dysfunction. Despite a well-defined senescent…”
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Empagliflozin reduces arrhythmogenic effects in rat neonatal and human iPSC-derived cardiomyocytes and improves cytosolic calcium handling at least partially independent of NHE1
Published in Scientific reports (29-05-2023)“…The antidiabetic agent class of sodium-glucose cotransporter 2 (SGLT2) inhibitors confer unprecedented cardiovascular benefits beyond glycemic control,…”
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Mesenchymal Stromal Cell-Based Products: Challenges and Clinical Therapeutic Options
Published in International journal of molecular sciences (01-06-2024)“…Mesenchymal stromal cell (MSC)-based advanced therapy medicinal products (ATMPs) are being tried in a vast range of clinical applications. These cells can be…”
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10
Advanced cell and gene therapies in cardiology
Published in EBioMedicine (01-05-2024)“…We review the evidence for the presence of stem/progenitor cells in the heart and the preclinical and clinical data using diverse cell types for the therapy of…”
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11
Author Correction: Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice
Published in Nature communications (08-12-2021)Get full text
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12
Heart regeneration:Past,present and future
Published in World journal of cardiology (26-05-2010)“…The heart has been considered a post-mitotic organ without regenerative capacity for most of the last century.We review the evidence that led to this…”
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13
Modelling premature cardiac aging with induced pluripotent stem cells from a hutchinson-gilford Progeria Syndrome patient
Published in Frontiers in physiology (23-11-2022)“…Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder that causes accelerated aging and a high risk of cardiovascular complications. However,…”
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14
The evolution of Brazilian Health Sciences and the present situation
Published in Lancet Regional Health - Americas (Online) (01-11-2021)Get full text
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15
Tissue-engineered human embryonic stem cell-containing cardiac patches: evaluating recellularization of decellularized matrix
Published in Journal of tissue engineering (2020)“…Decellularized cardiac extracellular matrix scaffolds with preserved composition and architecture can be used in tissue engineering to reproduce the complex…”
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Gene Expression Changes Associated with Myocarditis and Fibrosis in Hearts of Mice with Chronic Chagasic Cardiomyopathy
Published in The Journal of infectious diseases (15-08-2010)“…Chronic chagasic cardiomyopathy is a leading cause of heart failure in Latin American countries. About 30% of Trypanosoma cruzi–infected individuals develop…”
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17
Proteomics in the World of Induced Pluripotent Stem Cells
Published in Cells (Basel, Switzerland) (11-07-2019)“…Omics approaches have significantly impacted knowledge about molecular signaling pathways driving cell function. Induced pluripotent stem cells (iPSC) have…”
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18
Stem Cell-Based Therapies in Chagasic Cardiomyopathy
Published in BioMed research international (01-01-2015)“…Chagas disease is caused by Trypanosoma cruzi and can lead to a dilated cardiomyopathy decades after the prime infection by the parasite. As with other dilated…”
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Cardioprotective Properties of Humoral Factors Released From Rat Hearts Subject to Ischemic Preconditioning
Published in Journal of cardiovascular pharmacology (01-04-2007)“…Myocardial protection can be achieved by transfer of coronary effluent from ischemically preconditioned to non-preconditioned hearts. This study was designed…”
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New Cardiomyokine Reduces Myocardial Ischemia/Reperfusion Injury by PI3K-AKT Pathway Via a Putative KDEL-Receptor Binding
Published in Journal of the American Heart Association (05-01-2021)“…Background CDNF (cerebral dopamine neurotrophic factor) belongs to a new family of neurotrophic factors that exert systemic beneficial effects beyond the…”
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