Search Results - "Caruso, Lisa Beatrice"

Functional heterogeneity as reflected by topological parameters in a classical protein molecular model: t4 phage lysozyme by Caruso, Lisa Beatrice, Giuliani, Alessandro, Colosimo, Alfredo

“…A systematic comparison with the Wild-Type (WT) of one-point mutants of bacteriophage T4 lysozyme was carried out using as difference markers the topological…”
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Three-Dimensional Chromatin Structure of the EBV Genome: A Crucial Factor in Viral Infection by Caruso, Lisa Beatrice, Maestri, Davide, Tempera, Italo

“…Epstein-Barr Virus (EBV) is a human gamma-herpesvirus that is widespread worldwide. To this day, about 200,000 cancer cases per year are attributed to EBV…”
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The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activity by Morgan, Sarah M., Tanizawa, Hideki, Caruso, Lisa Beatrice, Hulse, Michael, Kossenkov, Andrew, Madzo, Jozef, Keith, Kelsey, Tan, Yinfei, Boyle, Sarah, Lieberman, Paul M., Tempera, Italo

“…Epstein-Barr virus (EBV) persists in human B-cells by maintaining its chromatinized episomes within the nucleus. We have previously shown that cellular factor…”
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The nuclear lamina binds the EBV genome during latency and regulates viral gene expression by Caruso, Lisa Beatrice, Guo, Rui, Keith, Kelsey, Madzo, Jozef, Maestri, Davide, Boyle, Sarah, Wasserman, Jason, Kossenkov, Andrew, Gewurz, Benjamin E, Tempera, Italo

“…The Epstein Barr virus (EBV) infects almost 95% of the population worldwide. While typically asymptomatic, EBV latent infection is associated with several…”
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Decitabine disrupts EBV genomic epiallele DNA methylation patterns around CTCF binding sites to increase chromatin accessibility and lytic transcription in gastric cancer by Preston-Alp, Sarah, Caruso, Lisa Beatrice, Su, Chenhe, Keith, Kelsey, Soldan, Samantha S, Maestri, Davide, Madzo, Jozef, Kossenkov, Andrew, Napoletani, Giorgia, Gewurz, Benjamin, Lieberman, Paul M, Tempera, Italo

“…Epstein-Barr virus (EBV) latency is controlled by epigenetic silencing by DNA methylation [5-methyl cytosine (5mC)], histone modifications, and chromatin…”
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TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment by Le, Bac Viet, Podszywalow-Bartnicka, Paulina, Maifrede, Silvia, Sullivan-Reed, Katherine, Nieborowska-Skorska, Margaret, Golovine, Konstantin, Yao, Juo-Chin, Nejati, Reza, Cai, Kathy Q., Caruso, Lisa Beatrice, Swatler, Julian, Dabrowski, Michal, Lian, Zhaorui, Valent, Peter, Paietta, Elisabeth M., Levine, Ross L., Fernandez, Hugo F., Tallman, Martin S., Litzow, Mark R., Huang, Jian, Challen, Grant A., Link, Daniel, Tempera, Italo, Wasik, Mariusz A., Piwocka, Katarzyna, Skorski, Tomasz

“…Synthetic lethality triggered by PARP inhibitor (PARPi) yields promising therapeutic results. Unfortunately, tumor cells acquire PARPi resistance, which is…”
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Epstein-Barr Virus-Encoded Latent Membrane Protein 1 and B-Cell Growth Transformation Induce Lipogenesis through Fatty Acid Synthase by Hulse, Michael, Johnson, Sarah M, Boyle, Sarah, Caruso, Lisa Beatrice, Tempera, Italo

“…Latent membrane protein 1 (LMP1) is the major transforming protein of Epstein-Barr virus (EBV) and is critical for EBV-induced B-cell transformation Several…”
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The nuclear lamina binds the EBV genome during latency and regulates viral gene expression by Lisa Beatrice Caruso, Rui Guo, Kelsey Keith, Jozef Madzo, Davide Maestri, Sarah Boyle, Jason Wasserman, Andrew Kossenkov, Benjamin E Gewurz, Italo Tempera

“…The Epstein Barr virus (EBV) infects almost 95% of the population worldwide. While typically asymptomatic, EBV latent infection is associated with several…”
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Poly(ADP-ribosylated) proteins in β-amyloid peptide-stimulated microglial cells by Correani, Virginia, Martire, Sara, Mignogna, Giuseppina, Caruso, Lisa Beatrice, Tempera, Italo, Giorgi, Alessandra, Grieco, Maddalena, Mosca, Luciana, Schininà, M.Eugenia, Maras, Bruno, d'Erme, Maria

“…[Display omitted] Amyloid-treated microglia prime and sustain neuroinflammatory processes in the central nervous system activating different signalling…”
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TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors by Maifrede, Silvia, Le, Bac Viet, Nieborowska-Skorska, Margaret, Golovine, Konstantin, Sullivan-Reed, Katherine, Dunuwille, Wangisa M B, Nacson, Joseph, Hulse, Michael, Keith, Kelsey, Madzo, Jozef, Caruso, Lisa Beatrice, Gazze, Zachary, Lian, Zhaorui, Padella, Antonella, Chitrala, Kumaraswamy N, Bartholdy, Boris A, Matlawska-Wasowska, Ksenia, Di Marcantonio, Daniela, Simonetti, Giorgia, Greiner, Georg, Sykes, Stephen M, Valent, Peter, Paietta, Elisabeth M, Tallman, Martin S, Fernandez, Hugo F, Litzow, Mark R, Minden, Mark D, Huang, Jian, Martinelli, Giovanni, Vassiliou, George S, Tempera, Italo, Piwocka, Katarzyna, Johnson, Neil, Challen, Grant A, Skorski, Tomasz

“…Somatic variants in and are founding mutations in hematological malignancies that affect the epigenetic regulation of DNA methylation. Mutations in both genes…”
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TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors by Maifrede, Silvia, Le, Bac Viet, Nieborowska-Skorska, Margaret, Golovine, Konstantin, Sullivan-Reed, Katherine, Dunuwille, Wangisa M.B., Nacson, Joseph, Hulse, Michael, Caruso, Lisa Beatrice, Gazze, Zachary, Lian, Zhaorui, Padella, Antonella, Chitrala, Kumaraswamy, Bartholdy, Boris, Matlawska-Wasowska, Ksenia, Di Marcantonio, Daniela, Simonetti, Giorgia, Greiner, Georg, Sykes, Stephen M., Valent, Peter, Paietta, Elisabeth M., Fernandez, Hugo F, Tallman, Martin S., Litzow, Mark, Minden, Mark D., Huang, Jian, Martinelli, Giovanni, Vassiliou, George S., Tempera, Italo, Piwocka, Katarzyna, Johnson, Neil, Challen, Grant, Skorski, Tomasz

“…Somatic variants in TET2 and DNMT3A are founding mutations in hematological malignancies that both affect the epigenetic regulation of DNA methylation…”
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