Search Results - "Cartularo, Laura"
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Molecular Mechanisms of Malignant Transformation by Low Dose Cadmium in Normal Human Bronchial Epithelial Cells
Published in PloS one (17-05-2016)“…Cadmium is a carcinogenic metal, the mechanisms of which are not fully understood. In this study, human bronchial epithelial cells were transformed with…”
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Journal Article -
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SATB2 expression increased anchorage-independent growth and cell migration in human bronchial epithelial cells
Published in Toxicology and applied pharmacology (15-02-2016)“…The special AT-rich sequence-binding protein 2 (SATB2) is a protein that binds to the nuclear matrix attachment region of the cell and regulates gene…”
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Journal Article -
3
Gene expression and pathway analysis of human hepatocellular carcinoma cells treated with cadmium
Published in Toxicology and applied pharmacology (01-11-2015)“…Cadmium (Cd) is a toxic and carcinogenic metal naturally occurring in the Earth's crust. A common route of human exposure is via diet and cadmium accumulates…”
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Journal Article -
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O 6-Methylguanine induces altered proteins at the level of transcription in human cells
Published in Nucleic acids research (01-12-2010)Get full text
Journal Article -
5
Tungsten-induced carcinogenesis in human bronchial epithelial cells
Published in Toxicology and applied pharmacology (01-10-2015)“…Metals such as arsenic, cadmium, beryllium, and nickel are known human carcinogens; however, other transition metals, such as tungsten (W), remain relatively…”
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Journal Article -
6
Genetic instability associated with loop or stem-loop structures within transcription units can be independent of nucleotide excision repair
Published in Nucleic acids research (20-04-2018)“…Abstract Simple sequence repeats (SSRs) are found throughout the genome, and under some conditions can change in length over time. Germline and somatic…”
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Journal Article -
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Nucleotide Excision Repair and Transcription-coupled DNA Repair Abrogate the Impact of DNA Damage on Transcription
Published in The Journal of biological chemistry (08-01-2016)“…DNA adducts derived from carcinogenic polycyclic aromatic hydrocarbons like benzo[a]pyrene (B[a]P) and benzo[c]phenanthrene (B[c]Ph) impede replication and…”
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Journal Article -
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Investigating the Molecular Events Associated with Malignant Transformation and Carcinogenesis by Cadmium Treatmen
Published 01-01-2016“…Cadmium is a toxic and carcinogenic metal nearly ubiquitous in the environment. In this study, human hepatocellular carcinoma cells were treated with cadmium…”
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Dissertation -
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O⁶-Methylguanine induces altered proteins at the level of transcription in human cells
Published in Nucleic acids research (01-12-2010)“…O⁶-Methylguanine (O⁶-meG), which is produced in DNA following exposure to methylating agents, instructs human RNA polymerase II to mis-insert bases opposite…”
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Journal Article