Search Results - "Cartron, Pierre‐Francois"

High hydrostatic pressure induces immunogenic cell death in human tumor cells by Fucikova, Jitka, Moserova, Irena, Truxova, Iva, Hermanova, Ivana, Vancurova, Irena, Partlova, Simona, Fialova, Anna, Sojka, Ludek, Cartron, Pierre‐Francois, Houska, Milan, Rob, Lukas, Bartunkova, Jirina, Spisek, Radek

“…Recent studies have identified molecular events characteristic of immunogenic cell death (ICD), including surface exposure of calreticulin (CRT), the heat…”
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Folate Supplementation Limits the Aggressiveness of Glioma via the Remethylation of DNA Repeats Element and Genes Governing Apoptosis and Proliferation by HERVOUET, Eric, DEBIEN, Emilie, CAMPION, Loic, CHARBORD, Jeremie, MENANTEAU, Jean, VALLETTE, Francois M, CARTRON, Pierre-Francois

“…Purpose: We have investigated whether the folate supplementation could be used to limit the aggressiveness of glioma through the DNA remethylation because ( a…”
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The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent by Brenner, Carmen, Luciani, Judith, Bizet, Martin, Ndlovu, Matladi, Josseaux, Eleonore, Dedeurwaerder, Sarah, Calonne, Emilie, Putmans, Pascale, Cartron, Pierre-Francois, Defrance, Matthieu, Fuks, François, Deplus, Rachel

“…DNA methylation and histone modifications are key epigenetic regulators of gene expression, and tight connections are known between the two. DNA…”
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From 1957 to Nowadays: A Brief History of Epigenetics by Peixoto, Paul, Cartron, Pierre-François, Serandour, Aurélien A, Hervouet, Eric

“…Due to the spectacular number of studies focusing on epigenetics in the last few decades, and particularly for the last few years, the availability of a…”
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Dormant, quiescent, tolerant and persister cells: Four synonyms for the same target in cancer by Vallette, François M., Olivier, Christophe, Lézot, Frédéric, Oliver, Lisa, Cochonneau, Denis, Lalier, Lisenn, Cartron, Pierre-François, Heymann, Dominique

“…[Display omitted] Although many drugs/treatments are now available for most diseases, too often, resistance to these treatments impedes complete therapeutic…”
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An Anti-apoptotic Viral Protein That Recruits Bax to Mitochondria by Poncet, Delphine, Larochette, Nathanael, Pauleau, Anne-Laure, Boya, Patricia, Jalil, Abdel-Ali, Cartron, Pierre-Francois, Vallette, Francois, Schnebelen, Céline, Bartle, Laura M, Skaletskaya, Anna, Boutolleau, David, Martinou, Jean-Claude, Goldmacher, Victor S, Kroemer, Guido, Zamzami, Naoufal

“…The viral mitochondria-localized inhibitor of apoptosis (vMIA), encoded by the UL37 gene of human cytomegalovirus, inhibits apoptosis-associated mitochondrial…”
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TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis by Lalier, Lisenn, Mignard, Vincent, Joalland, Marie-Pierre, Lanoé, Didier, Cartron, Pierre-François, Manon, Stéphen, Vallette, François M.

“…In this work, we have explored the subcellular localization of Bcl2, a major antiapoptotic protein. In U251 glioma cells, we found that Bcl2 is localized…”
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Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma by Hervouet, Eric, Peixoto, Paul, Delage-Mourroux, Régis, Boyer-Guittaut, Michaël, Cartron, Pierre-François

“…Our current view of DNA methylation processes is strongly moving: First, even if it was generally admitted that DNMT3A and DNMT3B are associated with de novo…”
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Characterization of circulating tumor cells as a reflection of the tumor heterogeneity: myth or reality? by Brown, Hannah K., Tellez-Gabriel, Marta, Cartron, Pierre-François, Vallette, François M., Heymann, Marie-Francoise, Heymann, Dominique

“…•Circulating tumor cells are highly heterogeneous in a spatial and temporal manner.•Circulating-tumor cells are a reflection of the tumor tissue at a fixed…”
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Cytosine methylation of mature microRNAs inhibits their functions and is associated with poor prognosis in glioblastoma multiforme by Cheray, Mathilde, Etcheverry, Amandine, Jacques, Camille, Pacaud, Romain, Bougras-Cartron, Gwenola, Aubry, Marc, Denoual, Florent, Peterlongo, Pierre, Nadaradjane, Arulraj, Briand, Joséphine, Akcha, Farida, Heymann, Dominique, Vallette, François M, Mosser, Jean, Ory, Benjamin, Cartron, Pierre-François

“…Literature reports that mature microRNA (miRNA) can be methylated at adenosine, guanosine and cytosine. However, the molecular mechanisms involved in cytosine…”
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Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation by Myrianthopoulos, Vassilios, Cartron, Pierre Francois, Liutkevičiūtė, Zita, Klimašauskas, Saulius, Matulis, Daumantas, Bronner, Christian, Martinet, Nadine, Mikros, Emmanuel

“…Ubiquitin-like protein UHRF1 that contains PHD and RING finger domain 1 is a key epigenetic protein enabling maintenance of the DNA methylation status through…”
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Anti-PD1 therapy induces lymphocyte-derived exosomal miRNA-4315 release inhibiting Bim-mediated apoptosis of tumor cells by Guyon, Nina, Garnier, Delphine, Briand, Joséphine, Nadaradjane, Arulraj, Bougras-Cartron, Gwenola, Raimbourg, Judith, Campone, Mario, Heymann, Dominique, Vallette, François M., Frenel, Jean-Sébastien, Cartron, Pierre-François

“…Anti-PD1 immunotherapy, as a single agent or in combination with standard chemotherapies, has significantly improved the outcome of many patients with cancers…”
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Glyphosate Primes Mammary Cells for Tumorigenesis by Reprogramming the Epigenome in a TET3-Dependent Manner by Duforestel, Manon, Nadaradjane, Arulraj, Bougras-Cartron, Gwenola, Briand, Joséphine, Olivier, Christophe, Frenel, Jean-Sébastien, Vallette, François M., Lelièvre, Sophie A., Cartron, Pierre-François

“…The acknowledgment that pollutants might influence the epigenome raises serious concerns regarding their long-term impact on the development of chronic…”
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Identification of a transient state during the acquisition of temozolomide resistance in glioblastoma by Rabé, Marion, Dumont, Solenne, Álvarez-Arenas, Arturo, Janati, Hicham, Belmonte-Beitia, Juan, Calvo, Gabriel F., Thibault-Carpentier, Christelle, Séry, Quentin, Chauvin, Cynthia, Joalland, Noémie, Briand, Floriane, Blandin, Stéphanie, Scotet, Emmanuel, Pecqueur, Claire, Clairambault, Jean, Oliver, Lisa, Perez-Garcia, Victor, Nadaradjane, Arulraj, Cartron, Pierre-François, Gratas, Catherine, Vallette, François M.

“…Drug resistance limits the therapeutic efficacy in cancers and leads to tumor recurrence through ill-defined mechanisms. Glioblastoma (GBM) are the deadliest…”
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Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation by Hervouet, Eric, Vallette, François M., Cartron, Pierre-François

“…Epigenetic gene inactivation in mammalian cells involves many silencing mechanisms. One of these mechanisms is the transcriptional repression by targeted…”
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Adenosine Methylation Level of miR-125a-5p Promotes Anti-PD-1 Therapy Escape through the Regulation of IGSF11/VSIG3 Expression by Bougras-Cartron, Gwenola, Nadaradjane, Arulraj, Joalland, Marie-Pierre, Lalier-Bretaudeau, Lisenn, Raimbourg, Judith, Cartron, Pierre-François

“…Despite encouraging anti-tumour activity in lung cancer, anti-PD-1 therapy has encountered increasing resistance to treatment. Several companion diagnostic…”
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Amelioration of experimental autoimmune encephalomyelitis by in vivo reprogramming of macrophages using pro-resolving factors by Gauthier, Thierry, Martin-Rodriguez, Omayra, Chagué, Cécile, Daoui, Anna, Ceroi, Adam, Varin, Alexis, Bonnefoy, Francis, Valmary-Degano, Séverine, Couturier, Mélanie, Behlke, Susanne, Saas, Philippe, Cartron, Pierre-François, Perruche, Sylvain

“…Reinstating inflammation resolution represents an innovative concept to regain inflammation control in diseases marked by chronic inflammation. While most…”
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Tracking Targets of Dynamic Super-Enhancers in Vitro to Better Characterize Osteoclastogenesis and to Evaluate the Effect of Diuron on the Maturation of Human Bone Cells by Tesfaye, Robel A, Lavaud, Melanie, Charrier, Céline, Brounais-Le Royer, Bénédicte, Cartron, Pierre-François, Verrecchia, Franck, Baud'huin, Marc, Lamoureux, François, Georges, Steven, Ory, Benjamin

“…Osteoclasts are major actors in the maintenance of bone homeostasis. The full functional maturation of osteoclasts from monocyte lineage cells is essential for…”
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Epigenetic regulation of estrogen signaling in breast cancer by Hervouet, Eric, Cartron, Pierre-François, Jouvenot, Michèle, Delage-Mourroux, Régis

“…Estrogen signaling is mediated by ERα and ERβ in hormone dependent, breast cancer (BC). Over the last decade the implication of epigenetic pathways in BC…”
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Bax activation and mitochondrial insertion during apoptosis by Lalier, Lisenn, Cartron, Pierre-François, Juin, Philippe, Nedelkina, Svetlana, Manon, Stephen, Bechinger, Burkhart, Vallette, François M

“…The mitochondrial apoptotic pathway is a highly regulated biological mechanism which determines cell fate. It is defined as a cascade of events, going from an…”
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