Search Results - "Cartic, Sharon"

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  1. 1
    Identification and optimization of a novel series of selective PIP5K inhibitors

    Identification and optimization of a novel series of selective PIP5K inhibitors by Andrews, David M., Cartic, Sharon, Cosulich, Sabina, Divecha, Nullin, Faulder, Paul, Flemington, Vikki, Kern, Oliver, Kettle, Jason G., MacDonald, Ellen, McKelvie, Jennifer, Pike, Kurt G., Roberts, Bryan, Rowlinson, Rachel, Smith, James M., Stockley, Martin, Swarbrick, Martin E., Treinies, Iris, Waring, Michael J.

    Published in Bioorganic & medicinal chemistry (15-01-2022)
    “…[Display omitted] Phosphatidyl inositol (4,5)-bisphosphate (PI(4,5)P2) plays several key roles in human biology and the lipid kinase that produces PI(4,5)P2,…”
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    Development of (4-Cyanophenyl)glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1

    Development of (4-Cyanophenyl)glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1 by Mould, Daniel P, Alli, Cristina, Bremberg, Ulf, Cartic, Sharon, Jordan, Allan M, Geitmann, Matthis, Maiques-Diaz, Alba, McGonagle, Alison E, Somervaille, Tim C. P, Spencer, Gary J, Turlais, Fabrice, Ogilvie, Donald

    Published in Journal of medicinal chemistry (12-10-2017)
    “…Inhibition of lysine specific demethylase 1 (LSD1) has been shown to induce the differentiation of leukemia stem cells in acute myeloid leukemia (AML)…”
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