Search Results - "Carter, Mark B"

Cell-Specific Delivery of Diverse Cargos by Bacteriophage MS2 Virus-like Particles by Ashley, Carlee E, Carnes, Eric C, Phillips, Genevieve K, Durfee, Paul N, Buley, Mekensey D, Lino, Christopher A, Padilla, David P, Phillips, Brandy, Carter, Mark B, Willman, Cheryl L, Brinker, C. Jeffrey, Caldeira, Jerri do Carmo, Chackerian, Bryce, Wharton, Walker, Peabody, David S

“…Virus-like particles (VLPs) of bacteriophage MS2 possess numerous features that make them well-suited for use in targeted delivery of therapeutic and imaging…”
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The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers by Ashley, Carlee E., Carnes, Eric C., Phillips, Genevieve K., Padilla, David, Durfee, Paul N., Brown, Page A., Hanna, Tracey N., Liu, Juewen, Phillips, Brandy, Carter, Mark B., Carroll, Nick J., Jiang, Xingmao, Dunphy, Darren R., Willman, Cheryl L., Petsev, Dimiter N., Evans, Deborah G., Parikh, Atul N., Chackerian, Bryce, Wharton, Walker, Peabody, David S., Brinker, C. Jeffrey

“…Encapsulation of drugs within nanocarriers that selectively target malignant cells promises to mitigate side effects of conventional chemotherapy and to enable…”
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Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters by Strouse, J. Jacob, Ivnitski-Steele, Irena, Waller, Anna, Young, Susan M., Perez, Dominique, Evangelisti, Annette M., Ursu, Oleg, Bologa, Cristian G., Carter, Mark B., Salas, Virginia M., Tegos, George, Larson, Richard S., Oprea, Tudor I., Edwards, Bruce S., Sklar, Larry A.

“…ATP binding cassette (ABC) transmembrane efflux pumps such as P-glycoprotein (ABCB1), multidrug resistance protein 1 (ABCC1), and breast cancer resistance…”
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FRET detection of lymphocyte function-associated antigen-1 conformational extension by Chigaev, Alexandre, Smagley, Yelena, Haynes, Mark K, Ursu, Oleg, Bologa, Cristian G, Halip, Liliana, Oprea, Tudor, Waller, Anna, Carter, Mark B, Zhang, Yinan, Wang, Wei, Buranda, Tione, Sklar, Larry A

“…Lymphocyte function-associated antigen 1 (LFA-1, CD11a/CD18, αLβ2-integrin) and its ligands are essential for adhesion between T-cells and antigen-presenting…”
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Identification of isoxsuprine hydrochloride as a neuroprotectant in ischemic stroke through cell-based high-throughput screening by Hill, Jeff W, Thompson, Jeffrey F, Carter, Mark B, Edwards, Bruce S, Sklar, Larry A, Rosenberg, Gary A

“…Stroke is a leading cause of death and disability and treatment options are limited. A promising approach to accelerate the development of new therapeutics is…”
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Cluster cytometry for high‐capacity bioanalysis by Edwards, Bruce S., Zhu, Jingshu, Chen, Jun, Carter, Mark B., Thal, David M., Tesmer, John J.G., Graves, Steven W., Sklar, Larry A.

“…Flow cytometry specializes in high‐content measurements of cells and particles in suspension. Having long excelled in analytical throughput of single cells and…”
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Cyclic AMP efflux inhibitors as potential therapeutic agents for leukemia by Perez, Dominique R, Smagley, Yelena, Garcia, Matthew, Carter, Mark B, Evangelisti, Annette, Matlawska-Wasowska, Ksenia, Winter, Stuart S, Sklar, Larry A, Chigaev, Alexandre

“…Apoptotic evasion is a hallmark of cancer. We propose that some cancers may evade cell death by regulating 3'-5'-cyclic adenosine monophosphate (cAMP), which…”
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Flow cytometry for drug discovery, receptor pharmacology and high-throughput screening by Sklar, Larry A, Carter, Mark B, Edwards, Bruce S

“…Although flow cytometry is viewed as a mature technology, there have been dramatic advances in analysis capabilities, sorting, sample handling and sensitivity…”
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Simultaneous in vitro molecular screening of protein-peptide interactions by flow cytometry, using six Bcl-2 family proteins as examples by Simons, Peter C, Young, Susan M, Carter, Mark B, Waller, Anna, Zhai, Dayong, Reed, John C, Edwards, Bruce S, Sklar, Larry A

“…The B-cell lymphoma-2 (Bcl-2) family contains six antiapoptotic members, each with a hydrophobic pocket in which Bcl-2 homology region 3 (BH3) helices bind…”
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Consequences of the loss of p53, RB1, and PTEN: Relationship to gefitinib resistance in endometrial cancer by Albitar, Lina, Carter, Mark B, Davies, Suzy, Leslie, Kimberly K

“…Abstract Objective These studies demonstrate how loss of function mutations or downregulation of key tumor suppressors missing from type I and type II…”
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The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers by Ashley, Carlee E, Carnes, Eric C, Phillips, Genevieve K, Padilla, David, Durfee, Paul N, Brown, Page A, Hanna, Tracey N, Liu, Juewen, Phillips, Brandy, Carter, Mark B, Carroll, Nick J, Jiang, Xingmao, Dunphy, Darren R, Willman, Cheryl L, Petsev, Dimiter N, Evans, Deborah G, Parikh, Atul N, Chackerian, Bryce, Wharton, Walker, Peabody, David S, Brinker, C Jeffrey

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High throughput flow cytometry based yeast two‐hybrid array approach for large‐scale analysis of protein‐protein interactions by Chen, Jun, Carter, Mark B., Edwards, Bruce S., Cai, Hong, Sklar, Larry A.

“…The analysis of protein‐protein interactions is a key focus of proteomics efforts. The yeast two‐hybrid system (Y2H) has been the most commonly used method in…”
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Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair by Wu, Yang, Stauffer, Shaun R, Stanfield, Robyn L, Tapia, Phillip H, Ursu, Oleg, Fisher, Gregory W, Szent-Gyorgyi, Christopher, Evangelisti, Annette, Waller, Anna, Strouse, J Jacob, Carter, Mark B, Bologa, Cristian, Gouveia, Kristine, Poslusney, Mike, Waggoner, Alan S, Lindsley, Craig W, Jarvik, Jonathan W, Sklar, Larry A

“…A new class of biosensors, fluorogen activating proteins (FAPs), has been successfully used to track receptor trafficking in live cells. Unlike the traditional…”
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Identification of a Small Molecule Yeast TORC1 Inhibitor with a Multiplex Screen Based on Flow Cytometry by Chen, Jun, Young, Susan M, Allen, Chris, Seeber, Andrew, Péli-Gulli, Marie-Pierre, Panchaud, Nicolas, Waller, Anna, Ursu, Oleg, Yao, Tuanli, Golden, Jennifer E, Strouse, J. Jacob, Carter, Mark B, Kang, Huining, Bologa, Cristian G, Foutz, Terry D, Edwards, Bruce S, Peterson, Blake R, Aubé, Jeffrey, Werner-Washburne, Margaret, Loewith, Robbie J, De Virgilio, Claudio, Sklar, Larry A

“…TOR (target of rapamycin) is a serine/threonine kinase, evolutionarily conserved from yeast to human, which functions as a fundamental controller of cell…”
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High-throughput screen for the chemical inhibitors of antiapoptotic bcl-2 family proteins by multiplex flow cytometry by Curpan, Ramona F, Simons, Peter C, Zhai, Dayong, Young, Susan M, Carter, Mark B, Bologa, Cristian G, Oprea, Tudor I, Satterthwait, Arnold C, Reed, John C, Edwards, Bruce S, Sklar, Larry A

“…The human Bcl-2 family includes six antiapoptotic members (Bcl-2, Bcl-B, Bcl-W, Bcl-X(L), Bfl-1, and Mcl-1) and many proapoptotic members, wherein a balance…”
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A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry by Strouse, J Jacob, Ivnitski-Steele, Irena, Khawaja, Hadya M, Perez, Dominique, Ricci, Jerec, Yao, Tuanli, Weiner, Warren S, Schroeder, Chad E, Simpson, Denise S, Maki, Brooks E, Li, Kelin, Golden, Jennifer E, Foutz, Terry D, Waller, Anna, Evangelisti, Annette M, Young, Susan M, Chavez, Stephanie E, Garcia, Matthew J, Ursu, Oleg, Bologa, Cristian G, Carter, Mark B, Salas, Virginia M, Gouveia, Kristine, Tegos, George P, Oprea, Tudor I, Edwards, Bruce S, Aubé, Jeffrey, Larson, Richard S, Sklar, Larry A

“…Chemotherapeutics tumor resistance is a principal reason for treatment failure, and clinical and experimental data indicate that multidrug transporters such as…”
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Development of a high throughput, bead-based flow cytometry panel for T-helper cell cytokine quantitation by O’Rourke, John, Weldon, Caroline, Keenan, Lisa, Carter, mark B

“…Abstract Upon T-cell activation, naïve CD4+ cells differentiate into various types of T-helper (Th) cells, which is influenced by the cytokine milieu present…”
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Erratum: The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers by Ashley, Carlee E., Carnes, Eric C., Phillips, Genevieve K., Padilla, David, Durfee, Paul N., Brown, Page A., Hanna, Tracey N., Liu, Juewen, Phillips, Brandy, Carter, Mark B., Carroll, Nick J., Jiang, Xingmao, Dunphy, Darren R., Willman, Cheryl L., Petsev, Dimiter N., Evans, Deborah G., Parikh, Atul N., Chackerian, Bryce, Wharton, Walker, Peabody, David S., Brinker, C. Jeffrey

“…Nature Materials 10, 389–397 (2011); published online 17 April 2011; corrected online 10 May 2011. In the version of this Letter originally published, in Fig…”
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The Targeted Delivery of Multicomponent Cargos to Cancer Cells via Nanoporous Particle-Supported Lipid Bilayers by Ashley, Carlee E., Carnes, Eric C., Phillips, Genevieve K., Padilla, David, Durfee, Paul N., Brown, Page A., Hanna, Tracey N., Liu, Juewen, Phillips, Brandy, Carter, Mark B., Carroll, Nick J., Jiang, Xingmao, Dunphy, Darren R., Willman, Cheryl L., Petsev, Dimiter N., Evans, Deborah G., Parikh, Atul N., Chackerian, Bryce, Wharton, Walker, Peabody, David S., Brinker, C. Jeffrey

“…Encapsulation of drugs within nanocarriers that selectively target malignant cells promises to mitigate side effects of conventional chemotherapy and to enable…”
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The Targeted Delivery of Multicomponent Cargos to Cancer Cells via Nanoporous Particle-Supported Lipid Bilayers by Ashley, Carol S., Ashley, Carlee Erin, Carnes, Eric Christopher, Phillips, Genevieve K., Padilla, David, Durfee, Paul N., Brown, Page A., Hanna, Tracey N., Liu, Juewen, Phillips, Brandy, Carter, Mark B., Carroll, Nick J., Jiang, Xingmao, Dunphy, Darren, Willman, Cheryl L., Petsev, Dimiter N., Evans, Deborah G., Parikh, Atul N., Chackerian, Bryce, Wharton, Walker, Peabody, David S., Brinker, C. Jeffrey

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