Search Results - "Carter, Kevin"

Liposomal formulations of photosensitizers by Ghosh, Sanjana, Carter, Kevin A., Lovell, Jonathan F.

“…Photodynamic therapy (PDT) is a clinical ablation modality to treat cancers and other diseases. PDT involves administration of a photosensitizer, followed by…”
Get full text

Chemophototherapy: An Emerging Treatment Option for Solid Tumors by Luo, Dandan, Carter, Kevin A., Miranda, Dyego, Lovell, Jonathan F.

“…Near infrared (NIR) light penetrates human tissues with limited depth, thereby providing a method to safely deliver non‐ionizing radiation to well‐defined…”
Get full text

Doxorubicin encapsulated in stealth liposomes conferred with light-triggered drug release by Luo, Dandan, Carter, Kevin A, Razi, Aida, Geng, Jumin, Shao, Shuai, Giraldo, Daniel, Sunar, Ulas, Ortega, Joaquin, Lovell, Jonathan F

“…Abstract Stealth liposomes can be used to extend the blood circulation time of encapsulated therapeutics. Inclusion of 2 molar % porphyrin-phospholipid (PoP)…”
Get full text

Porphyrin–phospholipid liposomes permeabilized by near-infrared light by Carter, Kevin A., Shao, Shuai, Hoopes, Matthew I., Luo, Dandan, Ahsan, Bilal, Grigoryants, Vladimir M., Song, Wentao, Huang, Haoyuan, Zhang, Guojian, Pandey, Ravindra K., Geng, Jumin, Pfeifer, Blaine A., Scholes, Charles P., Ortega, Joaquin, Karttunen, Mikko, Lovell, Jonathan F.

“…The delivery of therapeutic compounds to target tissues is a central challenge in treating disease. Externally controlled drug release systems hold potential…”
Get full text

Common Sleep Disorders in Children by Carter, Kevin A., DO, Hathaway, Nathanael E., MD, Lettieri, Christine F., MD

“…Up to 50% of children will experience a sleep problem. Early identification of sleep problems may prevent negative consequences, such as daytime sleepiness,…”
Get full text

Rapid Light-Triggered Drug Release in Liposomes Containing Small Amounts of Unsaturated and Porphyrin-Phospholipids by Luo, Dandan, Li, Nasi, Carter, Kevin A., Lin, Cuiyan, Geng, Jumin, Shao, Shuai, Huang, Wei-Chiao, Qin, Yueling, Atilla-Gokcumen, G. Ekin, Lovell, Jonathan F.

“…Prompt membrane permeabilization is a requisite for liposomes designed for local stimuli‐induced intravascular release of therapeutic payloads. Incorporation…”
Get full text

A malaria vaccine adjuvant based on recombinant antigen binding to liposomes by Huang, Wei-Chiao, Deng, Bingbing, Lin, Cuiyan, Carter, Kevin A., Geng, Jumin, Razi, Aida, He, Xuedan, Chitgupi, Upendra, Federizon, Jasmin, Sun, Boyang, Long, Carole A., Ortega, Joaquin, Dutta, Sheetij, King, C. Richter, Miura, Kazutoyo, Lee, Shwu-Maan, Lovell, Jonathan F.

“…Pfs25 is a malaria transmission-blocking vaccine antigen candidate, but its apparently limited immunogenicity in humans has hindered clinical development…”
Get full text

Surfactant‐Stripped Micelles for NIR‐II Photoacoustic Imaging through 12 cm of Breast Tissue and Whole Human Breasts by Chitgupi, Upendra, Nyayapathi, Nikhila, Kim, Jeesu, Wang, Depeng, Sun, Boyang, Li, Changning, Carter, Kevin, Huang, Wei‐Chiao, Kim, Chulhong, Xia, Jun, Lovell, Jonathan F.

“…Surfactant‐stripped micelles are formed from a commercially available cyanine fluoroalkylphosphate (CyFaP) salt dye and used for high contrast photoacoustic…”
Get full text

Pharmacokinetics and pharmacodynamics of liposomal chemophototherapy with short drug-light intervals by Luo, Dandan, Carter, Kevin A., Molins, Emilie A.G., Straubinger, Ninfa L., Geng, Jumin, Shao, Shuai, Jusko, William J., Straubinger, Robert M., Lovell, Jonathan F.

“…Chemophototherapy (CPT) merges photodynamic therapy with chemotherapy and can substantially enhance drug delivery. Using a singular liposomal formulation for…”
Get full text

Multicolor Liposome Mixtures for Selective and Selectable Cargo Release by Chitgupi, Upendra, Shao, Shuai, Carter, Kevin A, Huang, Wei-Chiao, Lovell, Jonathan F

“…Many approaches exist for stimuli-triggered cargo release from nanocarriers, but few can provide for on-demand release of multiple payloads, selectively. Here,…”
Get full text

Porphyrin-phospholipid liposomes with tunable leakiness by Luo, Dandan, Carter, Kevin A., Razi, Aida, Geng, Jumin, Shao, Shuai, Lin, Cuiyan, Ortega, Joaquin, Lovell, Jonathan F.

“…Drug bioavailability is a key consideration for drug delivery systems. When loaded with doxorubicin, liposomes containing 5 molar % porphyrin-phospholipid…”
Get full text

Short Drug–Light Intervals Improve Liposomal Chemophototherapy in Mice Bearing MIA PaCa‑2 Xenografts by Luo, Dandan, Carter, Kevin A, Geng, Jumin, He, Xuedan, Lovell, Jonathan F

“…Chemophototherapy (CPT) is an emerging tumor treatment that combines phototherapy and chemotherapy. Long-circulating (LC) liposomes can stably incorporate 2…”
Get full text

Loading and releasing ciprofloxacin in photoactivatable liposomes by Ghosh, Sanjana, Qi, Ruiquan, Carter, Kevin A., Zhang, Guojian, Pfeifer, Blaine A., Lovell, Jonathan F.

“…•Ciprofloxacin was loaded into photoactivatable liposomes containing porphyrin-phospholipid.•A formulation was optimized for antibiotic loading, stability and…”
Get full text

Metal Chelation Modulates Phototherapeutic Properties of Mitoxantrone-Loaded Porphyrin–Phospholipid Liposomes by Carter, Kevin A, Wang, Sophie, Geng, Jumin, Luo, Dandan, Shao, Shuai, Lovell, Jonathan F

“…Liposomes incorporating porphyrin–phospholipid (PoP) can be formulated to release entrapped contents in response to near-infrared (NIR) laser irradiation…”
Get full text

Blood Interactions, Pharmacokinetics, and Depth-Dependent Ablation of Rat Mammary Tumors with Photoactivatable, Liposomal Doxorubicin by Carter, Kevin A, Luo, Dandan, Geng, Jumin, Stern, Stephan T, Lovell, Jonathan F

“…Photosensitizers can be integrated with drug delivery vehicles to develop chemophototherapy agents with antitumor synergy between chemo- and photocomponents…”
Get full text

Nanomedical engineering: shaping future nanomedicines by Luo, Dandan, Carter, Kevin A., Lovell, Jonathan F.

“…Preclinical research in the field of nanomedicine continues to produce a steady stream of new nanoparticles with unique capabilities and complex properties…”
Get full text

Vessel-Targeted Chemophototherapy with Cationic Porphyrin-Phospholipid Liposomes by Luo, Dandan, Geng, Jumin, Li, Nasi, Carter, Kevin A, Shao, Shuai, Atilla-Gokcumen, G Ekin, Lovell, Jonathan F

“…Cationic liposomes have been used for targeted drug delivery to tumor blood vessels, via mechanisms that are not fully elucidated. Doxorubicin (Dox)-loaded…”
Get full text

Sphingomyelin Liposomes Containing Porphyrin-phospholipid for Irinotecan Chemophototherapy by Carter, Kevin A, Luo, Dandan, Razi, Aida, Geng, Jumin, Shao, Shuai, Ortega, Joaquin, Lovell, Jonathan F

“…Porphyrin-phospholipid (PoP) liposomes can entrap anti-cancer agents and release them in response to near infrared (NIR) light. Doxorubicin, when remotely…”
Get full text

Zwitterionic Cross-Linked Biodegradable Nanocapsules for Cancer Imaging by Sun, Haotian, Yan, Lingyue, Carter, Kevin A, Zhang, Jiaqi, Caserto, Julia S, Lovell, Jonathan F, Wu, Yun, Cheng, Chong

“…Zwitterionic cross-linked biodegradable nanocapsules (NCs) were synthesized for cancer imaging. A polylactide (PLA)-based diblock copolymer with two blocks…”
Get full text

Complications of Anorexia Nervosa by El-Baba, Rami M, Messerly, Charles, Tahawi, Ahmad, Carter, Kevin R

“…Multiple MRI studies have demonstrated that gray matter volumes are primarily affected in AN; this volume loss has been shown to be reversible with weight…”
Get full text